15190-66-6Relevant articles and documents
Montmorillonite KSF clay catalyzed one-pot synthesis of α-aminonitriles
Yadav,Subba Reddy,Eeshwaraiah,Srinivas
, p. 1767 - 1771 (2004)
Aryl imines, formed in situ from aldehydes and amines undergo smoothly nucleophilic addition with trimethylsilyl cyanide on the surface of montmorillonite KSF clay under mild reaction conditions to afford the corresponding α-aminonitriles in excellent yields. The solid acid can be recovered and recycled in subsequent reactions with a gradual decrease of activity.
Nitrile compound catalytic synthesis method and application thereof
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Paragraph 0109-0134; 0137, (2021/07/01)
The invention relates to the technical field of chemical catalytic synthesis, and particularly discloses a nitrile compound catalytic synthesis method and application thereof. According to the nitrile compound catalytic synthesis method, an alpha-aminonitrile or alpha-imino nitrile compound can be synthesized through selective reaction. The nitrile compound catalytic synthesis method has the advantages of simple and easily available raw materials, wide substrate applicability, mild conditions, high yield and the like, the yield is superior to that of a traditional chemical synthesis method, and the nitrile compound catalytic synthesis method is suitable for industrial production. The problems that an existing synthesis method of alpha-aminonitrile and alpha-imino nitrile compounds is not high in yield and does not meet the requirement of green chemistry are solved. Moreover, compared with a traditional chemical synthesis method, a heme system is more efficient and green in use, a substrate is simple and easy to obtain, a tedious catalysis step is not needed, a low-toxicity cyano donor is used, the substrate is wide in applicability, the requirement of green chemistry is met, and the heme system has a wide market prospect.
Copper-vitamin B6 coated on maghemite nanoparticles: A new convenient dual catalysis system to synthesize α-aminonitriles from benzyl alcohols
Esfandiary, Naghmeh,Nakisa, Athar,Radfar, Iman,Azizi, Kobra,Mehraban, Jamshid Azarnia,Heydari, Akbar
, (2018/10/15)
A novel and effective dual catalysis system, copper combined with pyridoxal phosphate, which is anchored in maghemite nanoparticles were designed and applied to synthesize α-aminonitriles from benzyl alcohols. This catalytic system has the potential ability to perform oxidation reactions and subsequently synthesize alpha-amino nitrile in a reaction environment. Thus, the purpose of this paper is introducing a heterogeneous, sustainable and recyclable catalytic system to perform reactions that require a transition metal catalyst and organocatalyst continuously to achieve a target molecule. The catalysis system is examined and investigated with seven useful analyses such as FT-IR, TGA, VSM, SEM, TEM, XRD, and ICP.
Role of (3-aminopropyl)tri alkoxysilanes in grafting of chlorosulphonic acid immobilized magnetic nanoparticles and their application as heterogeneous catalysts for the green synthesis of α-aminonitriles
Singh, Harminder,Rajput, Jaspreet Kaur,Arora, Priya,Jigyasa
, p. 84658 - 84671 (2016/10/31)
The surface modification of SiO2 coated Fe3O4 nanoparticles by grafting silane coupling agents is a highly significant approach to enhancing the interface interaction between the inorganic magnetic core and the organic fun
