15240-24-1

Basic information

• Product Name: copper(2+) salicylate
• Synonyms: copper(2+) salicylate;Benzoic acid, 2-hydroxy-, copper(2+) salt;Einecs 239-284-8
• CAS NO: 15240-24-1
• Molecular Formula: 2C₇H₅O₃*Cu
• Molecular Weight: 337.7716
• EINECS: 239-284-8
• Mol File: 15240-24-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 336.3°Cat760mmHg
• Flash Point: 144.5°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 4.45E-05mmHg at 25°C
• CAS DataBase Reference: copper(2+) salicylate(CAS DataBase Reference)
• NIST Chemistry Reference: copper(2+) salicylate(15240-24-1)
• EPA Substance Registry System: copper(2+) salicylate(15240-24-1)

Safety Data

• Hazardous Substances Data: 15240-24-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6O3.Cu/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);

Upstream product

• 69-72-7 salicylic acid 
• 54-21-7 sodium salicylate 
• 578-36-9 potassium salicylate 
• 7758-99-8 copper(II) sulfate 
• 6020-32-2 copper(II) salicylate tetrahydrate 
• 20427-59-2 copper hydroxide 
• 6046-93-1 copper(II) acetate monohydrate 
• 5908-78-1 barium salicylate 
• 6020-32-2 copper(II) salicylate dihydrate 

Downstream Products

• 3890-90-2 copper(II) o-hydroxybenzoate 
• 6020-32-2 copper(II) salicylate tetrahydrate 
• 244205-32-1 bis(1-methylimidazole-N⁽³⁾)bis(salicylato-O,O')copper(II) 
• 131494-74-1 bis(salicylato)bis(2-pyridylmethanol)copper(II) 

Relevant articles and documents

Synthesis, crystal structure and properties of copper(II) complexes with triethanolamine and carboxylic acids (succinic, salicylic, cinnamic)

The interaction of triethanolamine (TEA) with Cu(II) salts of salicylic, cinnamic and succinic acids was studied for the first time. The structure of the synthesized complexes was investigated by single-crystal X-ray diffraction. TEA complexes with Cu(II) salicylate (1) and cinnamate (2) are binuclear mixed ligand complexes, but interaction of TEA with Cu(II) succinate leads to the formation of cationic mononuclear complex—[Cu(TEA)2](C4H4O4) (3). Cu(II) complexes 1–3 were also characterized by physicochemical and spectroscopic methods. Their antimicrobial activity was investigated.

Promising Antifungal and Antibacterial Agents Based on 5-Aryl-2,2′-bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking

A series of new 5-aryl-2,2′-bipyridines and their (polyfluoro)salicylate complexes of Cu(II), Co(II) and Mn(II) were synthesized. Their antimicrobial activity was evaluated in vitro against six strains of Trichophytons, E. floccosum, M. canis, C. ablicans and Gram-negative bacteria N. gonorrhoeae. Among azo-ligands, Ph-bipy and Tol-bipy showed promising antifungal activity (minimum inhibitory concentration (MIC)4?2H)2(Tol-bipy)2] suppressed the growth of seven Candida strains at MIC 12–24 μM. [Cu(Sal?2H)(Ph-bipy)] and [Cu(SalF3?2H)(Ph-bipy)2] showed the promising anti-gonorrhoeae activity (MIC 4.2–5.2 μM). (Cu(SalFn?2H)(Tol-bipy)2], [Cu(SalF4?2H)(Ph-bipy)2] and [Cu(SalF3?2H)(Ph-bipy)2]) were found active against the bacteria of S. aureus, S. aureus MRSA and their biofilms (MIC 2.4–41.4 μM). The most active compounds were tested for toxicity in vitro against human embryonic kidney (HEK-293) cells and in vivo experiments with CD-1 mice.

Vibrational study of the salicylate interaction with metallic ions and surfaces

Infrared and Raman spectroscopy are used in this work to study the metallic complexes of salicylic acid with silver and copper, comparing the interaction between salicylate and the cations (Ag+ and Cu2+) in the metal complexes with the SERS spectra when adsorbed on colloidal metal surfaces of the same metals. The salicylate complexes with the above metals were compared to those of Na+, Fe3+ and Al3+ cations. A different interaction mechanism is deduced for salicylate in the metal complex and when adsorbed on the metal surface.