3890-90-2

Usage

Uses

Used in Anti-corrosive Coatings:
Copper salicylate, Cu(O3C7H4)2 is used as an active ingredient in anti-corrosive coatings for its ability to protect metal surfaces from oxidation and corrosion. Its chemical properties make it suitable for creating a protective barrier that prevents the formation of rust and other corrosive effects.
Used in Organic Compound Synthesis:
In the field of organic chemistry, copper salicylate, Cu(O3C7H4)2 is used as a catalyst or reagent in the synthesis of various organic compounds. Its unique coordination complex structure allows it to facilitate specific chemical reactions, leading to the formation of desired products.
Used in Pharmaceutical Research:
Copper salicylate, Cu(O3C7H4)2 is studied for its potential applications in medicine, particularly for its anti-inflammatory and antioxidant properties. Its ability to modulate inflammatory responses and combat oxidative stress makes it a promising candidate for the development of new pharmaceutical agents to treat various diseases and conditions.
Used in Antioxidant Formulations:
In the health and wellness industry, copper salicylate, Cu(O3C7H4)2 is used as an antioxidant in dietary supplements and skincare products. Its capacity to neutralize free radicals and protect cells from oxidative damage contributes to maintaining overall health and preventing premature aging.

Synthetic route

copper(II) nitrate + salicylic acid (69-72-7) → Cu(C6H4OHCOO)(1+) + disalicylatocuprate(II)(2-) + copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
In water formation of Cu(C6H4OCOO), Cu(C6H4OCOO)2(2-) and Cu(C6H4OHCOO)(1+) from Cu(2+) and hydrogen salicylate ions investigated; complex formation constants determined potentiometrically; chem. anal.;

potassium salicylate (578-36-9) + copper(II) sulfate (7758-99-8) → copper(II) salicylate (526-25-0, 7100-15-4, 15240-24-1, 20936-31-6, 59404-11-4) + copper(II) o-hydroxybenzoate (3890-90-2) + copper(II) salicylate tetrahydrate (6020-32-2, 13214-98-7)

Conditions	Yield
In water concd. or hot soln.;;
In water concd. or hot soln.;;

copper(II) salicylate (526-25-0, 7100-15-4, 15240-24-1, 20936-31-6, 59404-11-4) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
In neat (no solvent) byproducts: salicylic acid, phenol, CO2; heating at 250°C;; residue;;
In ethanol
In neat (no solvent) byproducts: salicylic acid, phenol, CO2; heating at 250°C;; residue;;

copper(II) mono(o-hydroxybenzoate) (monohydrate) (62320-94-9, 61841-85-8, 225373-00-2) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
heating at 97-98°C in a N2-stream for 1 h;;
In solid heating to 155°C; reaction followed by X-ray powder diffraction;
In neat (no solvent) dehydration in a N2-stream at 97-98°C or in air at about 100°C for 1 h;;
heating at 97-98°C in a N2-stream for 1 h;;
In neat (no solvent) dehydration in a N2-stream at 97-98°C or in air at about 100°C for 1 h;;

3Cu(2+)*2OH(1-)*2CO3(2-)=Cu(OH)2*2CuCO3 + salicylic acid (69-72-7) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
In not given byproducts: H2CO3, H2O; addn. of Cu-salt to soln. of acid, heating (3 - 4 h, stirring); filtration, washing (hot H2O), drying (room temp.);

barium salicylate (5908-78-1) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
Multi-step reaction with 3 steps 1: H2O / water 2: neat (no solvent) 3: acetone View Scheme

potassium salicylate (578-36-9) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
Multi-step reaction with 2 steps 1: not given 2: acetone View Scheme
Multi-step reaction with 2 steps 1: water 2: acetone View Scheme
Multi-step reaction with 3 steps 1: water 2: neat (no solvent) 3: acetone View Scheme
Multi-step reaction with 3 steps 1: H2O / water 2: neat (no solvent) 3: acetone View Scheme

sodium salicylate (54-21-7) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
Multi-step reaction with 3 steps 1: H2O / water 2: neat (no solvent) 3: acetone View Scheme

copper(II) salicylate tetrahydrate (6020-32-2, 13214-98-7) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
Multi-step reaction with 2 steps 1: neat (no solvent) 2: acetone View Scheme
Multi-step reaction with 2 steps 1: diethyl ether 2: neat (no solvent) View Scheme

salicylic acid (69-72-7) + copper dichloride → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
With ammonium hydroxide In water at 20℃; for 8h;	150 g

copper(II) sulfate (7758-99-8) + salicylic acid (69-72-7) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
With sodium hydroxide In water at 20℃; for 8h;	150 g

copper hydroxide (20427-59-2) + salicylic acid (69-72-7) → copper(II) o-hydroxybenzoate (3890-90-2)

Conditions	Yield
In water at 60 - 65℃; for 2h;

copper(II) o-hydroxybenzoate (3890-90-2) + 1,2-diaminopropan (78-90-0, 10424-38-1) → 1-methyl-N,N'-disalicyliden-ethanediyldiamine; copper (II)-salt

Conditions	Yield
With ethanol

diaminodecane (646-25-3) + copper(II) o-hydroxybenzoate (3890-90-2) → N,N'-disalicylidene-decanediyldiamine; copper (II)-salt

Conditions	Yield
With ethanol

(R)-1-phenyl-ethyl-amine (3886-69-9) + copper(II) o-hydroxybenzoate (3890-90-2) → salicylaldehyde-((R)-1-phenyl-ethylimine); copper (II)-salt

Conditions	Yield
With diethyl ether

(R)-Bornylamine (32511-34-5) + copper(II) o-hydroxybenzoate (3890-90-2) → (1R)-2endo-salicylidenamino-bornane; copper (II)-salt

Conditions	Yield
With methanol

(1R,3S)-1,2,2-trimethyl-1,3-cyclopentanediamine (116481-14-2) + copper(II) o-hydroxybenzoate (3890-90-2) → (2R)-2.5t-bis-salicylidenamino-1.1.2r-trimethyl-cyclopentane; copper (II)-salt

Conditions	Yield
With ethanol

2-chloroethanamine hydrochloride (870-24-6) + copper(II) o-hydroxybenzoate (3890-90-2) → 2-[(2-chloro-ethylimino)-methyl]-phenol; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

glycine ethyl ester hydrochloride (623-33-6) + copper(II) o-hydroxybenzoate (3890-90-2) → N-salicylidene-glycine ethyl ester; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

glycine n-butyl ester hydrochloride (13048-99-2) + copper(II) o-hydroxybenzoate (3890-90-2) → N-salicylidene-glycine butyl ester; copper (II)-salt

Conditions	Yield
With sodium acetate; butan-1-ol

L-lysine ethyl ester dihydrochloride (3844-53-9) + copper(II) o-hydroxybenzoate (3890-90-2) → Nα,Nε-disalicylidene-L-lysine ethyl ester; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + sodium sulfanilate (515-74-2) → N-salicylidene-sulfanilic acid ; copper (II)-sodium-salt

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + N-Phenylhydroxylamine (100-65-2) → copper(II) bis(2-oxy-1-benzylideneanilinate)

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + ethylenediamine (107-15-3) → N,N'-ethylenebis(salicylideneiminato)copper(II)

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + N,N-diethylethylenediamine (100-36-7) → N,N-diethyl-N'-salicyliden-ethylenediamine; mixed copper (II)-salt of 2-diethylamino-1-salicylidenamino-ethane and of salicylaldehyde

copper(II) o-hydroxybenzoate (3890-90-2) + urea (57-13-6) → disalicyliden-urea; copper (II)-salt

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + p,p'-diaminobiphenyl (92-87-5) → disalicylidene-benzidine; in chloroform soluble copper (II)-salt

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + naphthalene-1,8-diamine (479-27-6) → N,N'-disalicylidene-naphthalene-1,8-diyldiamine; copper (II)-salt

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + 2-iodo-ethylamine hydriodide → 2-[(2-iodo-ethylimino)-methyl]-phenol; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + (R)-sec-butylamine salt of/the/ (1R)-3endo-bromo-2-oxo-bornane-sulfonic acid-(8) → salicylaldehyde-((R)-sec-butylimine); copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + L-alanine ethyl ester hydrochloride → N-salicyliden-alanine ethyl ester; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate ohne erkennbares opt. Drehungsvermoegen ist erhalten worden;

copper(II) o-hydroxybenzoate (3890-90-2) + glycine-<(1R)-menthyl ester>-hydrochloride → N-salicylidene-glycine-((1R)-menthyl ester); copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + 1.3-diamino-propane dihydrochloride → N,N'-disalicylidene-propanediyldiamine; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + 1,4-diamino-butane dihydrochloride → N,N'-disalicylidene-butanediyldiamine; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + 1.5-diamino-pentane dihydrochloride → N,N'-disalicylidene-pentanediyldiamine; copper (II)-salt

Conditions	Yield
With sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + L-phenylalanine ethyl ester hydrochloride → N-salicylidene-phenylalanine ethyl ester; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + (R)-1.4-diamino-2-methyl-butane dihydrochloride → (R)-1,4-bis-salicylidenamino-2-methyl-butane; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + (1R)-1.2.2-trimethyl-1r.3c-bis-aminomethyl-cyclopentane hydrochloride → (1R)-1.2.2-trimethyl-1r.3c-bis-(salicylidenamino-methyl)-cyclopentane; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + L-lysine-dihydrochloride → Nα,Nε-disalicylidene-L-lysine ; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

copper(II) o-hydroxybenzoate (3890-90-2) + (2R)-2.5c-diamino-1.1.2r-trimethyl-cyclopentane → (2R)-2.5c-bis-salicylidenamino-1.1.2r-trimethyl-cyclopentane; copper (II)-salt

Conditions	Yield
With ethanol

copper(II) o-hydroxybenzoate (3890-90-2) + (R)-propylenediamine dihydrochloride → (R)-1.2-bis-salicylidenamino-propane; copper (II)-salt

Conditions	Yield
With ethanol; sodium acetate

water (7732-18-5) + copper(II) o-hydroxybenzoate (3890-90-2) → salicylic acid (69-72-7)

Upstream product

• 20427-59-2 copper hydroxide 
• 69-72-7 salicylic acid 
• 7758-99-8 copper(II) sulfate 
• 6020-32-2 copper(II) salicylate tetrahydrate 
• 54-21-7 sodium salicylate 
• 578-36-9 potassium salicylate 
• 5908-78-1 barium salicylate 
• 62320-94-9 copper(II) mono(o-hydroxybenzoate) (monohydrate) 
• 526-25-0 copper(II) salicylate 

Downstream Products

• 69-72-7 salicylic acid 

Relevant academic research and scientific papers

Preparation and thermal decomposition of copper(II) complexes with 4-methylemidazole

Simple and mixed compounds of the formulae Cu(4-Meim)2, CuSal(4-Meim), CuSal(4-Meim)2 and CuSalox(4-Meim)2, where 4-Meim=4-methylimidazole, Sal=(OC6H4COO)2-, Salox=(OC6H4CHNO)2- have been prepared. Thermal decomposition reactions have been established on the basis of thermal and X-ray analyses of these compounds. The pyrolysis proceeds in several (3-4) stages connected with the mass loss and exothermic effects. As a result of the last stage of decomposition CuO is formed.

USE OF CRYSTALLINE FORMS OF COPPER SALICYLATE FOR THE CONTROL OF HYTOPATHOGENIC BACTERIA

The use is described of crystalline forms of copper salicylate with a molar ratio between copper and salicylic acid of (1:1), selected from crystalline form I, crystalline form II or crystalline form III and/or mixtures thereof, and the relative agronomic compositions for the control of phytopathogenic bacteria.

Thermal investigation of the compounds of the copper(II) mono(o-hydroxybenzoate) with chelate ligands

Heteroligand complexes of copper(II) were obtained as a result of the reaction of Cu(II) mono (o-hydroxybenzoate) (monohydrate) with 8-hydroxyquinoline (HOx), o-aminophenol (NH2Ph) and 2,2'-dipyridyl (2,2'-dipy). The mixture of the mono compound with: Cu(II) di(o-aminobenzoate) or Cu(II) di(o-hydroxybenzaldoximate) were obtained by the reaction with o-aminobenzoic acid (H2A) and o-hydroxybenzaldoxime (H2Salox). The obtained compounds and their sinters were subjected to chemical, X-ray and thermal analyses.