578-36-9

Basic information

• Product Name: Potassium salicylate
• Synonyms: Salicylic acid potassium salt;POTASSIUM SALICYLATE;2-hydroxy-benzoicacimonopotassiumsalt;Benzoicacid,2-hydroxy-,monopotassiumsalt;SALICYCLICACIDPOTASSIUMSALT;POTASSIUMSALICYLATE,22%,POWDER;2-Hydroxybenzoic acid potassium salt;Salicylic acid 1-potassium salt
• CAS NO: 578-36-9
• Molecular Formula: C₇H₅O₃*K
• Molecular Weight: 176.21
• EINECS: 209-421-6
• Mol File: 578-36-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 336.3 °C at 760 mmHg
• Flash Point: 144.5 °C
• Appearance: white crystalline powder
• Density: g/cm³
• Vapor Pressure: 4.45E-05mmHg at 25°C
• CAS DataBase Reference: Potassium salicylate(CAS DataBase Reference)
• NIST Chemistry Reference: Potassium salicylate(578-36-9)
• EPA Substance Registry System: Potassium salicylate(578-36-9)

Safety Data

• Hazardous Substances Data: 578-36-9(Hazardous Substances Data)

Usage

Flammability and Explosibility

Notclassified

InChI:InChI=1/C7H6O3.K/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

Synthetic route

potassium salicylate + 1,1-dibromomethane (74-95-3) → methylene disalicylate salt (4540-66-3)

potassium salicylate (578-36-9) + N-(p-nitrophenyl)benzohydrazonoyl chloride (25939-13-3) → Benzoic acid N'-(2-hydroxy-benzoyl)-N'-(4-nitro-phenyl)-hydrazide

Conditions	Yield
In 1,4-dioxane for 25h; Heating;	85%

potassium salicylate (578-36-9) + acetophenone (98-86-2) → phenacyl 2-hydroxybenzoate (55153-16-7)

Conditions	Yield
With sodium carbonate at 20℃; for 0.5h; Ionic liquid;	84%

potassium salicylate (578-36-9) + allyl bromide (106-95-6) → allyl salicylate (10484-09-0)

Conditions	Yield
In N,N-dimethyl-formamide at 65℃; Kinetics; Solvent; Temperature;	84%

potassium salicylate (578-36-9) + 2-chloro-ethanol (107-07-3) → 2-hydroxyethyl salicylate (87-28-5)

Conditions	Yield
triethylamine at 130 - 135℃; for 3.5h;	83.5%

potassium salicylate (578-36-9) + ethylene dibromide (106-93-4) → 2,2'-<1,2-Ethandiylbis(oxy)>dibenzoesaeure (17354-62-0)

Conditions	Yield
In N,N-dimethyl-formamide for 0.25h; Heating;	72%

water (7732-18-5) + potassium salicylate (578-36-9) + dimethyl sulfate (77-78-1) → methyl salicylate (119-36-8)

water (7732-18-5) + potassium salicylate (578-36-9) + dimethyl sulfate (77-78-1) + alkali → 2-Methoxybenzoic acid (579-75-9) + methyl salicylate (119-36-8)

potassium salicylate (578-36-9) → carbon dioxide (124-38-9) + phenol (108-95-2) + dipotassium salt of/the/ p-oxy-benzoic acid + K2CO3

Conditions	Yield
at 210 - 220℃;

potassium salicylate (578-36-9) → phenol (108-95-2) + 4-hydroxy-benzoic acid (99-96-7)

Conditions	Yield
With carbon dioxide at 200℃; under 3750.3 Torr; for 1h;	A 34.2 % Chromat. B 40.6 % Chromat.

potassium salicylate (578-36-9) → 1,2-bis<2-(chloroformyl)phenoxy>ethane (150758-07-9)

Conditions	Yield
Multi-step reaction with 2 steps 1: 72 percent / dimethylformamide / 0.25 h / Heating 2: SOCl2 / 2 h / Heating View Scheme

potassium salicylate (578-36-9) → 5,6,7,8,9,10,16,17-octahydrodibenzo<1,4,8,11>dioxadiazacyclotetradecine-5,10-dione (150758-08-0)

Conditions	Yield
Multi-step reaction with 3 steps 1: 72 percent / dimethylformamide / 0.25 h / Heating 2: SOCl2 / 2 h / Heating 3: 3 percent / Et3N / CH2Cl2 / 3 h / Heating View Scheme

potassium salicylate (578-36-9) → 8,11-diethyl-5,6,7,8,9,10,16,17-octahydrodibenzo<1,4,8,11>dioxadiazacyclotetradecine-5,10-dione

Conditions	Yield
Multi-step reaction with 4 steps 1: 72 percent / dimethylformamide / 0.25 h / Heating 2: SOCl2 / 2 h / Heating 3: 3 percent / Et3N / CH2Cl2 / 3 h / Heating 4: 1.) NaH / 1.) THF, 50 deg C, 1 h, 2.) reflux, 24 h View Scheme

potassium salicylate (578-36-9) → 8,11-dibutyl-5,6,7,8,9,10,16,17-octahydrodibenzo<1,4,8,11>dioxadiazacyclotetradecine-5,10-dione

Conditions	Yield
Multi-step reaction with 4 steps 1: 72 percent / dimethylformamide / 0.25 h / Heating 2: SOCl2 / 2 h / Heating 3: 3 percent / Et3N / CH2Cl2 / 3 h / Heating 4: 1.) NaH / 1.) THF, 50 deg C, 1 h, 2.) reflux, 24 h View Scheme

potassium salicylate (578-36-9) → 8,11-dibenzyl-5,6,7,8,9,10,16,17-octahydrodibenzo<1,4,8,11>dioxadiazacyclotetradecine-5,10-dione

Conditions	Yield
Multi-step reaction with 4 steps 1: 72 percent / dimethylformamide / 0.25 h / Heating 2: SOCl2 / 2 h / Heating 3: 3 percent / Et3N / CH2Cl2 / 3 h / Heating 4: 1.) NaH / 1.) THF, 50 deg C, 1 h, 2.) reflux, 24 h View Scheme

potassium salicylate (578-36-9) + acryloyl chloride + salicylic acid (69-72-7) → acryloylsalicylic acid

Conditions	Yield
With potassium hydroxide; trifluoroacetic acid In methanol; diethyl ether; water; benzene

potassium salicylate (578-36-9) → 5-(5-chloro-2-benzoxazolyloxy) benzoic acid

Conditions	Yield
acetic acid

thorium(IV) nitrate + potassium salicylate (578-36-9) → thorium salicylate

Conditions	Yield
In not given addn. of K-salicylate to Th-nitrate soln. at boiling temp.;; pptn.;

potassium salicylate (578-36-9) → potassium trisalicylatoferrate(III) * 1.5 H2O

Conditions	Yield
With Fe acetate In ethanol

potassium salicylate (578-36-9) + copper(II) sulfate (7758-99-8) → copper(II) salicylate (526-25-0, 7100-15-4, 15240-24-1, 20936-31-6, 59404-11-4) + copper(II) o-hydroxybenzoate (3890-90-2) + copper(II) salicylate tetrahydrate (6020-32-2, 13214-98-7)

Conditions	Yield
In water concd. or hot soln.;;
In water concd. or hot soln.;;

potassium salicylate (578-36-9) + copper(II) sulfate (7758-99-8) → copper(II) salicylate (526-25-0, 7100-15-4, 15240-24-1, 20936-31-6, 59404-11-4)

Conditions	Yield
In not given concd. soln.;;
In not given concd. soln.;;

Downstream Products

• 118-58-1 benzyl salicylate 
• 606-45-1 2-methoxybenzoic acid methyl ester 
• 17354-62-0 2,2'-<1,2-Ethandiylbis(oxy)>dibenzoesaeure 
• 87-28-5 2-hydroxyethyl salicylate 
• 4540-66-3 methylene disalicylate salt 
• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 320-72-9 3,5-dichlorosalicylic acid 
• 590-29-4 potassium formate 
• 100-66-3 methoxybenzene 
• 100-09-4 4-methoxybenzoic acid 
• 108-95-2 phenol 
• 124-38-9 carbon dioxide 
• 10484-09-0 allyl salicylate 
• 6020-32-2 copper(II) salicylate tetrahydrate