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152533-46-5

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152533-46-5 Usage

General Description

(1r,2r,4s)-rel-7-boc-7-azabicyclo[2.2.1]heptan-2-ol is a chemical compound that belongs to the class of bicyclic organic compounds. It is a white crystalline solid with a molecular formula of C13H23NO3. (1r,2r,4s)-rel-7-boc-7-azabicyclo[2.2.1]heptan-2-ol has a bicyclic structure, with a seven-membered ring containing a nitrogen atom. It is commonly used as a building block in the synthesis of various organic compounds and pharmaceuticals. The Boc group on the amine functionality can be removed using acidic or basic conditions, making it a versatile intermediate in organic synthesis. Additionally, its stereochemistry (1r,2r,4s) refers to the specific arrangement of atoms in space, which is important in determining its biological activity and reactivity in chemical reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 152533-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,5,3 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 152533-46:
(8*1)+(7*5)+(6*2)+(5*5)+(4*3)+(3*3)+(2*4)+(1*6)=115
115 % 10 = 5
So 152533-46-5 is a valid CAS Registry Number.

152533-46-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl (1S,3R,4R)-3-hydroxy-7-azabicyclo[2.2.1]heptane-7-carboxylate

1.2 Other means of identification

Product number -
Other names (1R,2R,4S)-TERT-BUTYL 2-HYDROXY-7-AZABICYCLO[2.2.1]HEPTANE-7-CARBOXYLATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152533-46-5 SDS

152533-46-5Relevant articles and documents

Enantioselective approach to 7-azabicyclo[2.21lheptane ring systems using D-(-)quinic acid as the chiral educt: Application to the formal synthesis of (+)-epibatidine

Albertini, Enrichetta,Barco, Achille,Benetti, Simonetta,De Risi, Carmela,Pollini, Gian P.,Zanirato, Vinicio

, p. 681 - 684 (1997)

By utilizing, D-(-)-quinic acid as the chiral starting material the optically pure 7-[(1,1-dimethylethoxy)carbonyl]-7-azabicyclo[ 2.2.1]heptan-2-one 2, an advanced intermediate already taken to (+)-epibatidine 1, a non-opioid analgesic isolated from Ecuadorian poison frogs, was synthetized through a facile, regioselective intramolecular nucleophilic ring opening of a cyclic sulfate moiety.

PROTEASOME ACTIVITY ENHANCING COMPOUNDS

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Page/Page column 160; 163; 198-199, (2020/01/24)

The present invention is directed towards compounds having the Formula (lb) or the Formulae (III) and pharmaceutically acceptable salts, solvates and clathrates thereof, compositions thereof, as well as towards the use of said compounds in methods for the treatment of a condition associated with a dysfunction in proteostasis.

Substituted Imidazopyridines as HDM2 Inhibitors

-

, (2014/07/08)

The present invention provides substituted imidazopyridines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.

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