15375-19-6

Basic information

• Product Name: 5α-Androst-9(11)-ene-3,17-dione
• Synonyms: 5α-Androst-9(11)-ene-3,17-dione
• CAS NO: 15375-19-6
• Molecular Formula: C19H26O2
• Molecular Weight: 286.412
• Mol File: 15375-19-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5α-Androst-9(11)-ene-3,17-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5α-Androst-9(11)-ene-3,17-dione(15375-19-6)
• EPA Substance Registry System: 5α-Androst-9(11)-ene-3,17-dione(15375-19-6)

Safety Data

• Hazardous Substances Data: 15375-19-6(Hazardous Substances Data)

Usage

Uses

(5α)-Androst-9(11)-ene-3,17-dione is the impurity of Testosterone (T155000), which is the principal hormone of the testes, produced by the interstitial cells. Testosterone is the major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone that is required for normal male sexual differentiation.

Upstream product

• 15375-18-5 5α-androst-9,11-en-17-on-3β-ol 
• 64-19-7 acetic acid 
• 14043-47-1 3α-hydroxy-5α-androst-9(11)-en-17-one 
• 90177-90-5 C₂₄H₃₄O₅ 
• 3461-74-3 3β-hydroxy-5α-androst-9(11)-en-17-one 3-acetate 
• 3066-12-4 11α,17β-dihydroxyandrost-4-ene-3-one 
• 7801-30-1 11β,17β-dihydroxy-5α-androstan-3-one 
• 6173-32-6 17β-acetoxy-5α-androst-9(11)-en-3-one 
• 7778-25-8 17β-acetoxy-11β-hydroxy-5α-androstan-3-one 
• 1816-85-9 11β-hydroxytestosterone 
• 846-46-8 androstanedione 
• 24357-94-6 17β-hydroxy-5α-androst-9(11)-en-3-one 
• 141563-21-5 3,17-bis(ethylenedioxy)-5α-androst-9(11)-ene 
• 1035-69-4 androst-4,9⁽¹¹⁾-dien-3,17-dione 

Relevant articles and documents

A direct radioimmunoassay for 5α-androstane-3α,17β-diol 17-glucuronide

Synthesis of the 11α-hemiglutaryl derivative of 5α-androstane-3α,17β-diol 17-glucuronide (androstanediol-17G) starting from androsta-4,9(11)-diene-3,17-dione through a 10-step sequence and the preparation of its bovine serum albumin conjugate is described.By using this conjugate, antiserum was raised in rabbits which proved to be very specific for androstanediol-17G.A direct radioimmunoassay using a double antibody procedure is described for the measurement of androstanediol-17G from plasma without prior chromatography.Keywords: direct radioimmunoassay; androstanediol-17glucuronide; tritium as tracer

Microbiological Transformations Part 7. Microbiological Transformations of A-nor- and A-homo-5α-androstane derivatives with the fungus Cunninghamella elegans.

The microbiological transformation of 17β-hydroxy-A-nor-5α-androstan-2-one, 17β-hydroxy-A-homo-5α-androstan-3-one and 5α-androstan-3,17-dione, by Cunninghamella elegans is dominated by 9α-hydroxylation whereas 17β-hydroxy-5α-androstan-3-one undergoes predominant 7α-monohydroxylation. 9α-Hydroxy-5α-androstane-3,17-dione and 9α-hydroxy-A-homo-5α-androstane-3,17-dione were synthesised by a sequence involving 11α-hydroxylation of the corresponding 3,17-diones by Aspergillus ochraceous.