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Diethyl 2,6-dimethyl-4-phenyl-3,5-pyridinedicarboxylate is a complex organic compound with the chemical formula C20H21NO4. It is a derivative of pyridine, a heterocyclic aromatic compound, and features a pyridine ring with two methyl groups at the 2 and 6 positions, a phenyl group at the 4 position, and two carboxylate groups at the 3 and 5 positions. Diethyl 2,6-dimethyl-4-phenyl-3,5-pyridinedicarboxylate is typically synthesized through a series of chemical reactions and is used as an intermediate in the production of various pharmaceuticals and agrochemicals. Its structure provides a versatile platform for further functionalization, making it a valuable building block in organic synthesis.

1539-44-2

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1539-44-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1539-44-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,3 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1539-44:
(6*1)+(5*5)+(4*3)+(3*9)+(2*4)+(1*4)=82
82 % 10 = 2
So 1539-44-2 is a valid CAS Registry Number.

1539-44-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name diethyl 2,6-dimethyl-4-phenylpyridine-3,5-dicarboxylate

1.2 Other means of identification

Product number -
Other names Diethyl 2,6-dimethyl-4-phenyl-3,5-pyridinedicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1539-44-2 SDS

1539-44-2Relevant academic research and scientific papers

Aromatization of Hantzsch 1,4-dihydropyridines with I2-MeOH

Yadav,Subba Reddy,Sabitha,Kiran Kumar Reddy

, p. 1532 - 1534 (2000)

4-Alkyl or aryl substituted Hantzsch 1,4-dihydropyridines are aromatized to the corresponding pyridines in high yields by iodine in refluxing methanol. The method tolerates several substituents such as alkyl, benzyl, aryl and heterocyclic groups present i

Novel photoinduced aromatization of Hantzsch 1,4-dihydropyridines

Jin, Mei-Zhong,Yang, Li,Wu, Long-Min,Liu, You-Cheng,Liu, Zhong-Li

, p. 2451 - 2452 (1998)

4-Alkyl- and/or aryl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates (Hantzsch 1,4-dihydropyridines) are quantitatively oxidized to the corresponding pyridine derivatives by irradiation in CCl4 via a photoinduced electron transfer mechanism

Aluminum Chloride Promoted Hantzsch Reaction of N -Tosylhydrazones

Wang, Hu,Tang, Meng

, p. 4893 - 4898 (2017)

An aluminum chloride promoted Hantzsch reaction of N -tosylhydrazones has been developed. The reaction is general for a wide range of N -tosylhydrazones, and a series of 1,4-dihydropyridines (1,4-DHPs) were prepared in moderate to excellent yields.

Silica gel-supported bis(trimethylsilyl) chromate: Oxidation of 1,4-dihydropyridines to pyridines

Heravi, Majid M.,Derikvand, Fatemeh,Oskooie, Hossein A.,Shoar, Rahim Hekmat

, p. 77 - 82 (2006)

An efficient and convenient method for the oxidation of 1,4-dihydropyridines mediated by silica gel-supported bis(trimethylsilyl) chromate in refluxing CH2Cl2 is reported. Copyright Taylor & Francis LLC.

Activated carbon-promoted oxidative aromatization of hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolines using molecular oxygen

Nakamichi, Natsuki,Kawashita, Yuka,Hayashi, Masahiko

, p. 1015 - 1020 (2004)

In the presence of activated carbon, Hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolines were aromatized with molecular oxygen to the corresponding pyridines and pyrazoles in excellent yields.

Manganese dioxide supported onto HZSM-5 zeolite, a versatile reagent for the aromatization of Hantzsch 1,4-dihydropyridines

Heravi, Majid M.,Moosavi, Fahime Sadat Sh.,Beheshtiha, Yahya Sh.,Ghassemzadeh, Mitra

, p. 415 - 418 (2004)

A general and practical route for the fast and high yield aromatization of 1,4-dihydropyridine using a relatively benign oxidant, manganese dioxide under classical heating and microwave irradiation is described.

N,N′-ethylene-bis(benzoylacetoniminato) copper (II), Cu(C 22H22N2O2), a new reagent for aromatization of Hantzsch 1,4-dihydropyridines

Dehghanpour, Saeed,Heravi, Majid M.,Derikvand, Fatemeh

, p. 433 - 438 (2007)

A variety of Hantzsch 1,4-dihydropyridines were oxidized to their corresponding pyridines in high yields in the presence of Cu(C 22H22N2O2) in refluxing acetic acid.

KHSO4 supported onto bentonite, a versatile reagent for aromatization of Hantzsch 1,4-dihydropyridines

Heravi, Majid M.,Bakhtiari, Khadijeh,Oskooie, Hossein A.

, p. 579 - 581 (2007)

Aromatization of Hantzsch 1,4-dihydropyridines was promoted by KHSO 4, a relatively green chemical, supported onto bentonite to yield the corresponding pyridine derivatives in excellent yields. The reaction was carried out under mild and conven

Aromatization of Hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolines with HIO3 and I2O5 in water

Chai, Lingzhi,Zhao, Yankai,Sheng, Qiuju,Liu, Zhong-Quan

, p. 9283 - 9285 (2006)

Hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolines were converted to the corresponding pyridines and pyrazoles efficiently by the treatment of a catalytic amount of HIO3 or I2O5 in water.

Catalytic oxidation of 1,4-dihydropyridins by tetrabutylammonium periodate in the presence of manganese amino acid Schiff base

Karimipour, Gholam Reza,Nasr-Esfahani, Masoud,Valipour, Ghasem

, p. 415 - 417 (2007)

The amino acid Schiff base manganese complex (Tryp-Mn); 1, was prepared with L-tryptophan, salicylaldehyde and Mn(OAc)2.4H2O in methanol. In the presence of 1, 1,4-dihydropyridines (1,4-DHPs) were oxidised by n-Bu4NIO

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