154419-40-6

Basic information

• Product Name: ethyl 4-phenyl-3-methylquinoline-2-carboxylate
• Synonyms: ethyl 4-phenyl-3-methylquinoline-2-carboxylate
• CAS NO: 154419-40-6
• Molecular Weight: 291.349
• Mol File: 154419-40-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 4-phenyl-3-methylquinoline-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-phenyl-3-methylquinoline-2-carboxylate(154419-40-6)
• EPA Substance Registry System: ethyl 4-phenyl-3-methylquinoline-2-carboxylate(154419-40-6)

Safety Data

• Hazardous Substances Data: 154419-40-6(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 154419-39-3 4-phenyl-3-methylquinoline-2-carboxylic acid 
• 15933-07-0 Ethyl 2-oxobutanoate 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 1217189-30-4 ethyl 4-bromo-3-methylquinoline-2-carboxylate 
• 98-80-6 phenylboronic acid 
• 154419-41-7 3-bromomethyl-2-ethoxycarbonyl-4-phenylquinoline 
• 75-07-0 acetaldehyde 

Downstream Products

• 154419-39-3 4-phenyl-3-methylquinoline-2-carboxylic acid 
• 36796-96-0 2-benzyl-9-phenyl-1,2-dihydro-3H-pyrrolo[3,4-b]quinolin-3-one 
• 154419-33-7 N-benzyl-3-hydroxymethyl-4-phenylquinoline-2-carboxamide 
• 154419-34-8 N-benzyl-3-chloromethyl-4-phenylquinoline-2-carboxamide 
• 154419-32-6 9-phenylfurol<3,4-b>quinolin-3(1H)-one 
• 154419-41-7 3-bromomethyl-2-ethoxycarbonyl-4-phenylquinoline 

Relevant articles and documents

New iodinated quinoline-2-carboxamides for SPECT imaging of the translocator protein

With the aim of developing new SPECT imaging agents for the translocator protein (TSPO), a small library of iodinated quinoline-2-carboxamides have been prepared and tested for binding affinity with TSPO. N,N-Diethyl-3-iodomethyl-4-phenylquinoline-2-carboxamide was found to have excellent affinity (Ki 12.0 nM), comparable to that of the widely used TSPO imaging agent PK11195.

Synthesis of 4-Substituted 11-Phenyl-1,2,3,4-tetrahydro-5H-azepinoquinolin-5-one Derivatives as Potential Peripheral Benzodiazepine-Receptor Ligands

The synthesis of semirigid analogs of PK 11195, the highly specific peripheral benzodiazepine-receptor ligand, is reported.Compound (4) underwent the Wittig reaction with acetaldehyde to give olefin (7) which after allylic bromination was aminated to give