36796-96-0

Upstream product

• 154419-34-8 N-benzyl-3-chloromethyl-4-phenylquinoline-2-carboxamide 
• 154419-41-7 3-bromomethyl-2-ethoxycarbonyl-4-phenylquinoline 
• 100-46-9 benzylamine 
• 85422-43-1 9-phenylfuro[3,4-b]quinoline-1(3H)-one 
• 126334-84-7 ethyl 2-(chloromethyl)-4-phenylquinoline-3-carboxylate 
• 154419-39-3 4-phenyl-3-methylquinoline-2-carboxylic acid 
• 154419-31-5 2,3-bis(hydroxymethyl)-4-phenylquinoline 
• 154419-32-6 9-phenylfurol<3,4-b>quinolin-3(1H)-one 
• 154419-40-6 ethyl 4-phenyl-3-methylquinoline-2-carboxylate 
• 154419-33-7 N-benzyl-3-hydroxymethyl-4-phenylquinoline-2-carboxamide 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 62-53-3 aniline 

Downstream Products

• 154419-32-6 9-phenylfurol<3,4-b>quinolin-3(1H)-one 

Relevant academic research and scientific papers

Oxone promoted dehydrogenative Povarov cyclization of: N -aryl glycine derivatives: An approach towards quinoline fused lactones and lactams

Oxone promoted intramolecular dehydrogenative imino Diels-Alder reaction (Povarov cyclization) of alkyne tethered N-aryl glycine esters and amides has been explored, thus affording biologically significant quinoline fused lactones and lactams. The reaction is simple, scalable, and high yielding (up to 88%). The method was further extended to prepare biologically important luotonin-A analogues and the quinoline core of uncialamycin.

SYNTHESIS OF 2-SUBSTITUTED 2,3-DIHYDRO-9-PHENYL-1H-PYRROLOQUINOLIN-3-ONES AS POTENTIAL PERIPHERAL BENZODIAZEPINE-RECEPTOR LIGANDS

Two synthetic routes to the achievement of the title compounds are described. 2-Chloromethyl-3-ethoxycarbonyl-4-phenylquinoline (4) was transformed into the corresponding lacton (5) which in two steps was converted into its isomeric lacton (7).Aminolysis