15447-62-8

Basic information

• Product Name: 5-Hexyn-1-one, 1-phenyl-
• Synonyms: 1-phenyl-5-hexyn-1-one;4-pentynyl phenyl ketone;1-phenyl-5-hexynone;5-Hexyn-1-one,1-phenyl;1-phenyl-hex-5-yn-1-one
• CAS NO: 15447-62-8
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Mol File: 15447-62-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 142-143 °C(Press: 14 Torr)
• Density: 1.008±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-Hexyn-1-one, 1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexyn-1-one, 1-phenyl-(15447-62-8)
• EPA Substance Registry System: 5-Hexyn-1-one, 1-phenyl-(15447-62-8)

Safety Data

• Hazardous Substances Data: 15447-62-8(Hazardous Substances Data)

Upstream product

• 116385-36-5 3-iodo-1-trimethylsiloxy-1-phenylpropene 
• 106-96-7 propargyl bromide 
• 768-03-6 Phenyl vinyl ketone 
• 38771-21-0 4-bromobut-1-yne 
• 98-86-2 acetophenone 
• 100-52-7 benzaldehyde 
• 935-64-8 1-phenyl-1-cyclobutanol 
• 2396-63-6 hepta-1,6-diyne 
• 133745-75-2 N-fluorobis(benzenesulfon)imide 
• 100-58-3 phenylmagnesium bromide 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 27005-97-6 6-phenyl-7-oxabicyclo[4.1.0]heptan-2-one 
• 504-02-9 1,3-cylohexanedione 
• 62269-48-1 3-[(trimethylsilyl)oxy]cyclohex-2-en-1-one 

Downstream Products

• 15289-08-4 8-Diaethylamino-1-phenyl-octin-⁽⁵⁾-on-⁽¹⁾ 
• 15288-93-4 1,1-Diphenyl-hexin-⁽⁵⁾-ol-⁽¹⁾ 
• 13983-43-2 1-Diaethylamino-2-benzoyl-hexin-⁽⁵⁾ 
• 22524-25-0 1-phenylhex-5-en-1-one 
• 87258-30-8 6-oxo-6-phenylhexanal 
• 1313885-32-3 6-cyclopentenyl-1-phenylhex-5-yn-1-one 
• 6303-82-8 1-phenylhexane-1,5-dione 
• 136954-19-3 1,6-diphenyl-hex-5-yn-1-one 
• 10345-87-6 3-phenylcyclohex-2-enone 

Relevant articles and documents

Chemiluminescence-promoted oxidation of alkyl enol ethers by NHPI under mild conditions and in the dark

The hydroperoxidation of alkyl enol ethers using N-hydroxyphthalimide and molecular oxygen occurred in the absence of catalyst, initiator, or light. The reaction proceeds through a radical mechanism that is initiated by N-hydroxyphthalimide-promoted autoxidation of the enol ether substrate. The resulting dioxetane products decompose in a chemiluminescent reaction that allows for photochemical activation of N-hydroxyphthalimide in the absence of other light sources.

Asymmetric Construction of Alkaloids by Employing a Key ω-Transaminase Cascade

An ω-transaminase-triggered intramolecular aza-Michael reaction has been employed for the preparation of cyclic β-enaminones in good yield and excellent enantio- and diastereoselectivity, starting from easily accessible prochiral ketoynones and commercially available enzymes. The powerful thermodynamic driving force associated with the spontaneous aza-Michael reaction effectively displaces the transaminase reaction equilibrium towards product formation, using only two equivalents of isopropylamine. To demonstrate the potential of this methodology, this biocatalytic aza-Michael step was combined with annulation chemistry, affording unique stereo-defined fused alkaloid architectures.

Tandem nucleophilic addition/fragmentation of vinylogous acyl nonaflates for the synthesis of functionalized alkynes, with new mechanistic insight

Vinylogous acyl nonaflates, like the corresponding triflates, are subject to nucleophile-triggered fragmentation as part of a tandem process for generating functionalized alkynes. Advantages to the use of nonaflates in lieu of triflates include cost and s