15501-38-9Relevant academic research and scientific papers
Ritter reactions in flow
Audiger, Logan,Watts, Kevin,Elmore, Simon C.,Robinson, Richard I.,Wirth, Thomas
scheme or table, p. 257 - 260 (2012/05/04)
Flow me a Ritter: Ritter reactions are performed in a simple microreactor setup using tert-butylacetate as versatile carbocation source. The protocol avoids the handling of large amounts of hot concentrated sulfuric acid as low concentrations are optimal for rapid access tert-butyl- or diphenylmethyl- protected amides. Copyright
Safe and efficient ritter reactions in flow
Brandt, Johan C.,Elmore, Simon C.,Robinson, Richard I.,Wirth, Thomas
experimental part, p. 3099 - 3103 (2011/02/25)
Efficient mixing, temperature control and small environmental exposures allow reactions carried out in microfluidic de-vices to perform superior to their batch-type counterparts in conventional flasks. The Ritter reaction has been optimised for flow conditions leading to short reaction times and higher yields and also is more feasible with regards to safety, productivity and tolerance towards substrate functionalities.
Metal-catalyzed organic photoreactions. Photoreaction of 2-chloroacetophenone derivatives with olefins in the presence of silver trifluoromethanesulfonate
Oh,Tamura,Sato
, p. 9687 - 9694 (2007/10/02)
UV-irradiation of 2-chloroacetophenones and olefins in the presence of silver triflate affords naphthalenone derivatives with high regio and stereoselectivity and chemical yields. A possible mechanism is proposed.
OXIDATION-REDUCTION MECHANISMS - INNER-SPHERE AND OUTER-SPHERE ELECTRON TRANSFER IN THE REDUCTION OF IRON(III), RUTHENIUM(III), AND OSMIUM(III) COMPLEXES BY ALKYL RADICALS. MECHANISMS -
Rollick,Kochi
, p. 1319 - 1330 (2007/10/02)
Alkyl radicals are readily oxidized by the tris(phenanthroline) and tris(bipyridine) complexes ML//3**3** plus of iron(III), ruthenium(III), and osmium(III) in acetonitrile solution, the second-order rate constants easily exceeding 10**6 M** minus **1s** minus **1 at 25 degree C. Two oxidative processes are identified as (a) ligand substitution on the coordinated 1,10-phenanthroline to yield various alkylphenanthrolines and (b) cation formation to afford alkenes and N-alkylacetamides (after hydrolysis). Cation formation is characterized by extensive skeletal rearrangement of neopentyl, isobutyl, and n-propyl groups, whereas ligand substitution by the same alkyl radicals occurs without any rearrangement.
