155380-11-3

Basic information

• Product Name: Methyl 2-(4-(hydroxyMethyl)phenyl)acetate
• Synonyms: Methyl 2-(4-(hydroxyMethyl)phenyl)acetate;methyl 4-(hydroxymethyl)phenylacetate
• CAS NO: 155380-11-3
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.20048
• Mol File: 155380-11-3.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 2-(4-(hydroxyMethyl)phenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(4-(hydroxyMethyl)phenyl)acetate(155380-11-3)
• EPA Substance Registry System: Methyl 2-(4-(hydroxyMethyl)phenyl)acetate(155380-11-3)

Safety Data

• Hazardous Substances Data: 155380-11-3(Hazardous Substances Data)

Usage

General Description

Methyl 2-(4-(hydroxymethyl)phenyl)acetate is an organic compound with the chemical formula C10H12O4. It is a colorless liquid with a fruity odor and is commonly used as a fragrance ingredient in various cosmetic and personal care products. Methyl 2-(4-(hydroxyMethyl)phenyl)acetate is synthesized through the esterification of 4-hydroxybenzyl alcohol with acetic acid, resulting in a compound with a pleasant, aromatic scent. It is also used in the manufacturing of perfumes, soaps, and other scented products due to its ability to provide a sweet, floral aroma. Additionally, it is utilized in the pharmaceutical industry as a flavoring agent in oral medications and in the food industry to add fragrance to various food and beverage products.

Upstream product

• 73401-74-8 4-hydroxymethylphenylacetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67-56-1 methanol 
• 7398-42-7 methyl 2-(4-(bromomethyl)phenyl)acetate 
• 74-88-4 methyl iodide 
• 622-47-9 4-tolylacetic acid 
• 13737-36-5 4-bromophenylacetic acid 

Downstream Products

• 1253955-08-6 methyl 2-(4-(((triisopropylsilyl)oxy)methyl)phenyl)acetate 
• 1253955-19-9 (S)-4-(3-((tert-butoxycarbonyl)amino)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate 
• 87077-46-1 1-(4-ethyl-phenyl)-2-methyl-propan-2-ol 
• 1253955-17-7 4-{3-[(tert-butoxycarbonyl)amino]-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl}benzyl 2,4-dimethylbenzoate 
• 1253955-20-2 4-{3-[(tert-butoxycarbonyl)amino]-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl}benzyl 2,4-dimethylbenzoate 
• 950502-41-7 [2-(2,6-dichloro-phenyl)-ethyl]-(4-{[2R-hydroxy-2-(4-hydroxy-2-oxo-2,3-dihydro-benzothiazol-7-yl)-ethylcarbamoyl]-methyl}-benzyl)-carbamic acid tert-butyl ester 
• 950502-40-6 [4-({tert-butoxycarbonyl-[2-(2,6-dichloro-phenyl)-ethyl]-amino}-methyl)-phenyl]-acetic acid 

Relevant articles and documents

SS-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THE SAME

A compound represented by Formula (I), a pharmaceutically acceptable salt or ester, hydrate, solvate or crystalline form thereof is provided: The compound represented by Formula (I) is a β-amino acid derivative, and in Formula (I): X is a single bond or O; Y is NH or C=O; Z is C=O, C=S, NH, W is C or N; A is a single bond, O, OH, OCH2, a heterocycle or N3; R1 is H or F; R2 is H, F, OH, CF3, CH2OH, CHO or ; R3 is H; n is 0 or 1; and m is 0 or 1.

IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME

Imidazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1- thione moiety.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity

Nicotinamide phosphoribosyltransferase (NAMPT) is a key enzyme involved in the recycling of nicotinamide to maintain adequate NAD levels inside the cells. It has been postulated to be a pharmacological target, as it is overexpressed in cancer cells as well as in inflammatory diseases. We describe the synthesis and characterization of a novel class of one-digit nanomolar NAMPT inhibitors based on in vitro characterization. The most active compound tested, 30c, displayed activity in xenograft and allograft models, strengthening the potential of NAMPT inhibitors as antitumoral drugs. Furthermore, in the present contribution we describe the ability of 30c to significantly improve the outcome of colitis in mice. Given that this is the first report of an effect of NAMPT inhibitors in colitis, this result paves the way for novel applications for this class of compounds.