155488-74-7

Upstream product

• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 
• 79027-28-4 (2S)-3-(benzyloxy)-2-methylpropanal 
• 618096-09-6 (2S,3S)-3-((S)-2-benzyloxy-1-methylethyl)oxirane-2-carbaldehyde 
• 81470-75-9 (Z)-(R)-5-Benzyloxy-4-methyl-pent-2-enoic acid methyl ester 
• 81470-72-6 (R)-ethyl (Z)-5-benzyloxy-4-methyl-2-pentenoate 
• 73814-74-1 (Z)-(R)-5-Benzyloxy-4-methyl-pent-2-en-1-ol 
• 73814-75-2 (2R,3S,4S)-5-benzyloxy-2,3-epoxy-4-methyl-1-pentanol 
• 155430-43-6 (E)-(4R,5S,6S)-ethyl 7-benzyloxy-4,5-epoxy-6-methyl-2-heptenoate 
• 75-24-1 trimethylaluminum 

Downstream Products

• 203458-71-3 [(4R,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-acetic acid ethyl ester 
• 155430-44-7 (E)-(4S,5R,6S)-7-benzyloxy-5-triethylsilyloxy-4,6-dimethyl-2-hepten-1-ol 
• 155430-45-8 (2R,3R,4R,5S,6S)-7-benzyloxy-2,3-epoxy-5-triethylsilyloxy-4,6-dimethyl-1-heptanol 
• 618095-86-6 (2S,3S,4S,5S,6S)-7-benzyloxy-5-triethylsilyloxy-2,4,6-trimethyl-1,3-heptanediol 
• 618096-11-0 2,2-Dimethyl-propionic acid (2S,3S,4S,5S,6S)-7-benzyloxy-3-hydroxy-2,4,6-trimethyl-5-triethylsilanyloxy-heptyl ester 
• 155430-54-9 2,2-Dimethyl-propionic acid (3S,4R,5R,6S,7R,8R,9S,10S)-11-benzyloxy-3-hydroxy-4,6,8,10-tetramethyl-5,7,9-tris-triethylsilanyloxy-undecyl ester 
• 155430-52-7 [(2R,3R)-3-((1R,2R,3S,4R,5R,6S,7S)-8-Benzyloxy-1,3,5,7-tetramethyl-2,4,6-tris-triethylsilanyloxy-octyl)-oxiranyl]-methanol 
• 155430-48-1 (E)-3-[(2S,3S)-3-((1S,2S,3R,4S,5S)-6-Benzyloxy-1,3,5-trimethyl-2,4-bis-triethylsilanyloxy-hexyl)-oxiranyl]-acrylic acid ethyl ester 
• 155430-53-8 (3S,4R,5R,6S,7R,8R,9S,10S)-11-Benzyloxy-4,6,8,10-tetramethyl-5,7,9-tris-triethylsilanyloxy-undecane-1,3-diol 
• 155430-50-5 (E)-(4R,5R,6S,7S,8R,9S,10S)-11-Benzyloxy-5,7,9-trihydroxy-4,6,8,10-tetramethyl-undec-2-enoic acid ethyl ester 
• 155430-49-2 (E)-3-[(2S,3S)-3-((1R,2R,3R,4S,5S)-6-Benzyloxy-2,4-dihydroxy-1,3,5-trimethyl-hexyl)-oxiranyl]-acrylic acid ethyl ester 
• 203630-43-7 (3S,4S,5R,6S,9S)-9-[(4S,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-6-(4-methoxy-benzyloxy)-3,5-dimethyl-dec-1-en-4-ol 
• 203630-42-6 (3R,4R,5R,6S,9S)-9-[(4S,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-6-(4-methoxy-benzyloxy)-3,5-dimethyl-dec-1-en-4-ol 

Relevant academic research and scientific papers

Total synthesis of scytophycin C. 1. Stereoselective syntheses of the C(1)-C(18) segment and the C(19)-C(31) segment

[Equation presented] Stereoselective total synthesis of scytophycin C, a marine 22-membered macrolide displaying potent activity against a variety of human carcinoma cell lines, has been reported in which the polypropionate structure bearing contiguous as

Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems

Expeditious and stereoselective synthesis of chiral trans-β-hydroxy-δ-lactone systems starting from γ,δ-epoxy acrylates is described which involves the regioselective ring opening of an epoxide and the intramolecular conjugate addition of a hemiacetal alkoxide anion of δ-hydroxy-α,β-unsaturated esters as key steps.

Synthesis of the C(19)-C(32) fragment of Scytophycin C via stereospecific methylation of γ,δ-epoxy acrylates with trimethylaluminum

The synthesis of the C(19) - C(32) fragment of Scytophycin C is described which features an iterative, stereospecific methylation of γ,δ-epoxy acrylates by trimethylaluminum and the use of Roush's (S,S)-diisopropyltartrate-E-crotylboronate.

Synthetic Studies on Polypropionate Antibiotics Based on the Stereospecific Methylation of γ,δ-Epoxy Acrylates by Trimethylaluminum. A Highly Stereoselective Construction of the Eight Contiguous Chiral Centers of Ansa-chains of Rifamycins

A highly stereoselective construction of the eight contiguous chiral centers of ansa-chains of rifamycins has been accomplished by the iterative use of the stereospecific methylation of γ,δ-epoxy acrylates by trimethylaluminum which was recently developed