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Usage

Uses

Used in Pharmaceutical Industry:
4-Amino-3-mercaptobenzoic acid HCl is used as a synthetic intermediate for the production of various pharmaceuticals, such as antibiotics and antiviral drugs. Its presence of an amino and thiol group facilitates the synthesis of these medicinal compounds, contributing to the development of new treatments for a range of diseases.
Used in Chemical Reactions:
As a reagent, 4-Amino-3-mercaptobenzoic acid HCl is utilized in various chemical reactions. Its functional groups enable it to participate in a wide array of chemical processes, making it a valuable component in the synthesis of different organic compounds.
Used in Dyes and Pigments Production:
4-Amino-3-mercaptobenzoic acid HCl is used as a building block in the production of dyes and pigments. Its chemical properties allow it to contribute to the color and stability of these products, which are used in a variety of applications, including textiles, paints, and plastics.
Used in Research and Development:
In the fields of biochemistry and medicinal chemistry, 4-Amino-3-mercaptobenzoic acid HCl has potential applications in research and development. Its unique structure and functional groups make it a promising candidate for the exploration of new chemical pathways and the discovery of novel therapeutic agents.

Upstream product

• 93-85-6 2-aminobenzothiazole-6-carboxylic acid 
• 18330-76-2 2-aminobenzothiazole-6-carboxylic acid hydrochloride 

Downstream Products

• 634602-34-9 methyl 4-amino-3-(methylsulfanyl)benzoate 
• 1126253-10-8 6-carboxy-2-(4'-fluorophenyl)-1,3-benzothiazole 
• 84092-99-9 2-mercaptobenzo[d]thiazole-6-carboxylic acid 
• 664324-19-0 2-(2-hydroxyphenyl)benzo[d]thiazole-6-carboxylic acid 
• 185540-75-4 (S)-2-{[4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonyl]-amino}-pentanedioic acid diethyl ester 
• 156578-99-3 (S)-2-{[4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonyl]-amino}-hexanedioic acid dimethyl ester 
• 185540-73-2 3-(2-Chloro-ethylsulfanyl)-4-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 185540-74-3 4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carboxylic acid methyl ester 
• 156578-98-2 4-tosyl-3,4-dihydro-2H-benzo[b][1,4]-thiazine-7-carboxylic acid 
• 1026651-61-5 4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonyl chloride 
• 93015-74-8 dimethyl 3,3'-disulfanediylbis(4-aminobenzoate) 
• 185540-71-0 4-Amino-3-(2-chloro-ethylsulfanyl)-benzoic acid 

Relevant academic research and scientific papers

Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling

Heteroaromatic sulfones react with cysteine via nucleophilic aromatic substitution, providing a mechanistically selective and irreversible scaffold for cysteine conjugation. Here we evaluate a library of heteroaromatic sulfides with different oxidation st

Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents

Oxidative stress is the product or aetiology of various multifactorial diseases; on the other hand, the development of multifunctional compounds is a recognized strategy for the control of complex diseases. To this end, a series of benzothiazole derivatives was synthesized and evaluated for their multifunctional effectiveness as antioxidant, sunscreen (filter), antifungal and antiproliferative agents. Compounds were easily synthesized via condensation reaction between 2-aminothiophenols and different benzaldehydes. SAR study, particularly in position 2 and 6 of benzothiazoles, led to the identification of 4g and 4k as very interesting potential compounds for the design of multifunctional drugs. In particular, compound 4g is the best blocker of hERG potassium channels expressed in HEK 293 cells exhibiting 60.32percent inhibition with IC50 = 4.79 μM.

Synthesis and evaluation of18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in alzheimer's disease

Imaging agents targeting amyloid β(Aβ) may be useful for early diagnosis and follow-up of treatment of patients with Alzheimer's disease (AD). Three of five tested 2-(4′-fluorophenyl)-1,3-benzothiazoles displayed high binding affinities for Aβ plaques in