1571-66-0

Basic information

• Product Name: 4-Amino-3-mercaptobenzoic acid HCl
• Synonyms: 4-Amino-3-mercaptobenzoic acid HCl;4-Amino-3-mercaptobenzoic acid hydrochloride;Benzoic acid, 4-aMino-3-Mercapto-, hydrochloride
• CAS NO: 1571-66-0
• Molecular Formula: C₇H₇NO₂S*ClH
• Molecular Weight: 205.66
• Mol File: 1571-66-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 288.5-290.0 °C
• Appearance: /
• CAS DataBase Reference: 4-Amino-3-mercaptobenzoic acid HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-mercaptobenzoic acid HCl(1571-66-0)
• EPA Substance Registry System: 4-Amino-3-mercaptobenzoic acid HCl(1571-66-0)

Safety Data

• Hazardous Substances Data: 1571-66-0(Hazardous Substances Data)

Usage

General Description

4-Amino-3-mercaptobenzoic acid HCl, also known as 4-Amino-3-mercaptobenzoic acid hydrochloride, is a chemical compound with the molecular formula C7H7NO2S?HCl. It is a synthetic intermediate used in the production of pharmaceuticals and organic compounds. 4-Amino-3-mercaptobenzoic acid HCl is a derivative of benzoic acid and contains an amino group and a thiol group, making it useful in the synthesis of antibiotics, antiviral drugs, and other pharmaceuticals. It is also used as a reagent in chemical reactions and as a building block in the production of dyes and pigments. Additionally, 4-Amino-3-mercaptobenzoic acid HCl has potential applications in research and development in the fields of biochemistry and medicinal chemistry.

Upstream product

• 18330-76-2 2-aminobenzothiazole-6-carboxylic acid hydrochloride 
• 93-85-6 2-aminobenzothiazole-6-carboxylic acid 

Downstream Products

• 185540-71-0 4-Amino-3-(2-chloro-ethylsulfanyl)-benzoic acid 
• 634602-34-9 methyl 4-amino-3-(methylsulfanyl)benzoate 
• 1126253-10-8 6-carboxy-2-(4'-fluorophenyl)-1,3-benzothiazole 
• 84092-99-9 2-mercaptobenzo[d]thiazole-6-carboxylic acid 
• 664324-19-0 2-(2-hydroxyphenyl)benzo[d]thiazole-6-carboxylic acid 
• 185540-75-4 (S)-2-{[4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonyl]-amino}-pentanedioic acid diethyl ester 
• 156578-99-3 (S)-2-{[4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonyl]-amino}-hexanedioic acid dimethyl ester 
• 185540-73-2 3-(2-Chloro-ethylsulfanyl)-4-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 185540-74-3 4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carboxylic acid methyl ester 
• 156578-98-2 4-tosyl-3,4-dihydro-2H-benzo[b][1,4]-thiazine-7-carboxylic acid 
• 1026651-61-5 4-(Toluene-4-sulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonyl chloride 
• 93015-74-8 dimethyl 3,3'-disulfanediylbis(4-aminobenzoate) 

Relevant articles and documents

Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents

Oxidative stress is the product or aetiology of various multifactorial diseases; on the other hand, the development of multifunctional compounds is a recognized strategy for the control of complex diseases. To this end, a series of benzothiazole derivatives was synthesized and evaluated for their multifunctional effectiveness as antioxidant, sunscreen (filter), antifungal and antiproliferative agents. Compounds were easily synthesized via condensation reaction between 2-aminothiophenols and different benzaldehydes. SAR study, particularly in position 2 and 6 of benzothiazoles, led to the identification of 4g and 4k as very interesting potential compounds for the design of multifunctional drugs. In particular, compound 4g is the best blocker of hERG potassium channels expressed in HEK 293 cells exhibiting 60.32percent inhibition with IC50 = 4.79 μM.

Synthesis and evaluation of18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in alzheimer's disease

Imaging agents targeting amyloid β(Aβ) may be useful for early diagnosis and follow-up of treatment of patients with Alzheimer's disease (AD). Three of five tested 2-(4′-fluorophenyl)-1,3-benzothiazoles displayed high binding affinities for Aβ plaques in