157119-18-1

Basic information

• Product Name: Benzeneacetyl chloride, 4-(dimethylamino)-alpha-oxo- (9CI)
• Synonyms: Benzeneacetyl chloride, 4-(dimethylamino)-alpha-oxo- (9CI)
• CAS NO: 157119-18-1
• Molecular Formula: C₁₀H₁₀ClNO₂
• Molecular Weight: 211.6449
• Product Categories: ACETYLHALIDE
• Mol File: 157119-18-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 348.8±44.0 °C(Predicted)
• Appearance: /
• Density: 1.263±0.06 g/cm3(Predicted)
• PKA: -1.43±0.12(Predicted)
• CAS DataBase Reference: Benzeneacetyl chloride, 4-(dimethylamino)-alpha-oxo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetyl chloride, 4-(dimethylamino)-alpha-oxo- (9CI)(157119-18-1)
• EPA Substance Registry System: Benzeneacetyl chloride, 4-(dimethylamino)-alpha-oxo- (9CI)(157119-18-1)

Safety Data

• Hazardous Substances Data: 157119-18-1(Hazardous Substances Data)

Upstream product

• 41116-24-9 ethyl 2-(4-(dimethylamino) phenyl)-2-oxoacetate 
• 121-69-7 N,N-dimethyl-aniline 
• 63756-72-9 2-(4-(dimethylamino)phenyl)-2-oxoacetic acid 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 889-37-2 N,N-dimethyl-4-((phenylimino)methyl)aniline 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 619-84-1 p-N,N-dimethylaminobenzoic acid 
• 63756-72-9 2-(4-(dimethylamino)phenyl)-2-oxoacetic acid 
• 4755-50-4 4-(dimethylamino)benzoyl chloride 
• 258345-35-6 methyl-4-dimethylaminophenylglyoxylate 

Relevant articles and documents

Sequential Cu-Catalyzed Four- and Five-Component Syntheses of Luminescent 3-Triazolylquinoxalines

3-Triazolylquinoxalines can be readily synthesized by applying two complementary synthetic protocols starting from heterocyclic π nucleophiles or (hetero)aryl glyoxylic acids in a consecutive four- or five-component reaction. Conceptually, the sequential use of a single cuprous salt for alkynylation and Cu-catalyzed alkyne-azide cycloaddition (CuAAC) in a one-pot fashion sets the stage for activation-alkynylation-cyclocondensation-CuAAC or glyoxylation-alkynylation-cyclocondensation-CuAAC sequences in good yields. The diversity-oriented generation of differently substituted 3-triazolylquinoxalines is an excellent entry to tunable emission solvatorchromic fluorophores with triazole ligation. The electronic structure, corroborated by DFT and TD-DFT calculations, rationalizes the charge transfer character of relevant absorptions and large Stokes shifts as well as the electronic innocence of the triazole substituents.