15732-27-1Relevant academic research and scientific papers
Optimization and antifungal activity of chalcone analogues
Tang, Xiaorong,Chen, Shaoling,Wang, Ling
experimental part, p. 2516 - 2518 (2012/09/08)
Using chalcone as a leading compound, a series of its analogues (compounds 1-16) were designed and synthesized. Their activity of antipathogenic fungi of plants has been evaluated in the laboratory. The results showed that these compounds had certain antifungal activity against Sclerotinia sclerotiorum and Botrytis cinerea. Among them, the inhibition of growth for 2-chloro-N- phenylbenzamide (compound 2) reached 92.6 and 90.1 % at a concentration of 100 mg L-1, respectively.
A simple copper-catalyzed synthesis of tertiary acyclic amides
Racine, Emilie,Monnier, Florian,Vors, Jean-Pierre,Taillefer, Marc
, p. 2818 - 2821 (2011/07/09)
The N-arylation of aromatic and aliphatic secondary acyclic amides, known to be poor nucleophiles, has been accomplished using a simple and cheap copper catalytic system. The corresponding tertiary acyclic amides, which can be found in numerous biologically active compounds, have been obtained in good to excellent yields.
REARRANGEMENT OF NITRONES TO AMIDES USING CHLOROSULFONYL ISOCYANATE
Joseph, Sajan P.,Dhar, D. N.
, p. 5979 - 5983 (2007/10/02)
Reaction of chlorosulfonyl isocyanate (CSI) with nitrones 1a-n and 5a,b has been studied. α,α,N-Triaryl nitrones 1a-n react with CSI to form the N,N-diaryl arylamides 3a-n and 4i-n in good yields.In the case of α-H,α,N-diaryl nitrones 5a,b however, two compounds viz., the rearranged product 11a,b and the 1,4-dihydro tetrazines 10a,b are formed.The effect of substituents on the rearrangement has been studied.It is found that the nature of the substituents has got a profound effect on the rearrangement.We have also noted that the rearrangement is independent of the syn or anti configurations of the nitrones.
