157366-46-6

Basic information

• Product Name: AKOS BH-2115
• Synonyms: AKOS BH-2115;2-(2-Methylphenyl)benzonitrile
• CAS NO: 157366-46-6
• Molecular Formula: C₁₄H₁₁N
• Molecular Weight: 193.24384
• Mol File: 157366-46-6.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 339.8 °C at 760 mmHg
• Flash Point: 160 °C
• Appearance: /
• Density: 1.09 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: AKOS BH-2115(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS BH-2115(157366-46-6)
• EPA Substance Registry System: AKOS BH-2115(157366-46-6)

Safety Data

• Hazardous Substances Data: 157366-46-6(Hazardous Substances Data)

Usage

General Description

AKOS BH-2115 is a chemical compound with the molecular formula C6H6O2S. It is known to be a sulfonamide derivative, which are often used as antibacterial agents in medicine. However, specific details about the properties and potential uses of AKOS BH-2115 are not widely available in the public domain. As such, further research and testing would be necessary to fully understand its applications and potential benefits.

Upstream product

• 873-32-5 2-Chlorobenzonitrile 
• 2042-37-7 o-cyanobromobenzene 
• 874-05-5 3-aminoindazole 
• 108-88-3 toluene 
• 4387-36-4 2-iodobenzonitrile 
• 16419-60-6 2-Methylphenylboronic acid 
• 615-37-2 ortho-methylphenyl iodide 
• 172732-52-4 o-cyanophenylboronic acid-1,3-propylene glycol ester 
• 138642-62-3 2-Cyanophenylboronic acid 
• 611-20-1 salicylonitrile 
• 15898-37-0 sodium 2-methylbenzenesulfinate 
• 138313-23-2 2-<(trifluoromethanesulfonyl)oxy>benzonitrile 
• 195062-59-0 2-methylphenylboronic acid pinacol ester 
• 95-46-5 2-methylphenyl bromide 

Downstream Products

• 947-73-9 9-Aminophenanthrene 
• 153850-89-6 (2'-methylbiphenyl-2-yl)methanamine 
• 1383378-68-4 2-methyl-3'-(p-tolyl)spiro[cyclohexa[2,5]diene-1,1'-isoindol]-4-one 

Relevant articles and documents

New air-stable planar chiral ferrocenyl monophosphine ligands: Suzuki cross-coupling of aryl chlorides and bromides

(Matrix presented) A novel class of planar chiral electron-rich monophosphine ligands has been developed. The modular design allows a short and efficient synthesis of an array of aryl-ferrocenyl derivatives carrying the donating bis(dicyclohexyl)phosphino moiety. These new ligands have successfully been applied in the palladium-catalyzed Suzuki cross-coupling of activated as well as nonactivated aryl chlorides at room temperature. The asymmetric coupling of an aryl bromide and an aryl boronic acid was also tested, giving ees up to 54%.

The Rational Design and Synthesis of Water-Soluble Thiourea Ligands for Recoverable Pd-Catalyzed Aerobic Aqueous Suzuki-Miyaura Reactions at Room Temperature

Eight precatalysts containing carboxylic-functionalized thiourea ligands are prepared and their activities and recyclability are evaluated in aerobic aqueous Suzuki-Miyaura reactions. A bulky monothiourea-Pd complex, functionalized with four carboxylic groups, shows the best activity and recyclability in the coupling of aryl bromides with arylboronic acids. The catalyst can be reused at least five times without any significant reduction in its catalytic activity. TEM analysis and the confirmed catalytic activity of the observed black precipitate reveal that Pd nanoparticles are formed during the reactions and are stabilized by the carboxylic-functionalized thiourea ligands.

Ruthenium-catalyzed hydrogenation of carbocyclic aromatic amines: Access to chiral exocyclic amines

The first highly enantioselective hydrogenation of carbocyclic aromatic amines has been successfully realized using in situ-generated chiral ruthenium complex as catalyst, affording facile access to chiral exocyclic amines with up to 98% ee.