157465-47-9Relevant academic research and scientific papers
Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid
Aicher, Thomas D.,Bebernitz, Gregory R.,Bell, Philip A.,Brand, Leonard J.,Dain, Jeremy G.,Deems, Rhonda,Fillers, William S.,Foley, James E.,Knorr, Douglas C.,Nadelson, Jeffrey,Otero, Dario A.,Simpson, Ronald,Strohschein, Robert J.,Young, Douglas A.
, p. 153 - 163 (2007/10/03)
SAH 51-641 (1) is a potent hypoglycemic agent, which acts by inhibiting hepatic gluconeogenesis. It is a prodrug of 4-(2,2-dimethyl-1- oxopropyl)benzoic acid (2) and 4-(2,2-dimethyl-1-hydroxypropyl)benzoic acid (3), which sequester coenzyme A (CoA) in the
