1575-73-1

Basic information

• Product Name: 2-ethylpent-4-enoic acid
• CAS NO: 1575-73-1
• Molecular Formula: C₇H₁₂O₂
• Molecular Weight: 128.169
• Mol File: 1575-73-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 209.9°C at 760 mmHg
• Flash Point: 107.3°C
• Density: 0.955g/cm³
• Vapor Pressure: 0.0788mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: 2-ethylpent-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethylpent-4-enoic acid(1575-73-1)
• EPA Substance Registry System: 2-ethylpent-4-enoic acid(1575-73-1)

Safety Data

• Hazardous Substances Data: 1575-73-1(Hazardous Substances Data)

Upstream product

• 591-87-7 Allyl acetate 
• 85287-67-8 2,2,6,6-tetramethyl-4-propylidene-3,5-dioxa-2,6-disilaheptane 
• 24964-76-9 triethyl orthobutyrate 
• 107-18-6 allyl alcohol 
• 2051-78-7 allyl butyrate 
• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 106-95-6 allyl bromide 
• 107-92-6 butyric acid 
• 80765-41-9 phenyl allylethylacetate 
• 42998-02-7 methyl 2-ethyl-4-pentenoate 
• 59726-37-3 diethyl allylethylmalonate 
• 67030-95-9 ethyl 2-ethyl-4-pentenoate 
• 74-96-4 ethyl bromide 
• 14035-70-2 2-Ethyl-but-3-en-1,1-dicarbonsaeure 

Downstream Products

• 85622-00-0 2-Ethyl-pent-4-enoyl chloride 
• 80765-41-9 phenyl allylethylacetate 
• 121074-25-7 (4R,5S)-3-((R)-2-Ethyl-pent-4-enoyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 121074-25-7 (4R,5S)-3-[(2S)-1-oxo-2-ethyl-4-pentenyl]-4-methyl-5-phenyl-2-oxazolidinone 
• 109704-79-2 (S)-3-Benzyl-4-((S)-2-hydroxymethyl-butyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylic acid methyl ester 
• 109704-79-2 (S)-3-Benzyl-4-((R)-2-hydroxymethyl-butyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylic acid methyl ester 
• 121074-31-5 N^b-benzyl-21-<(tert-butyldimethylsilyl)oxy>-D-seco-Ψ-vincadifformine 
• 121074-31-5 N^b-benzyl-21-<(tert-butyldimethylsilyl)oxy>-D-seco-Ψ-vincadifformine 
• 18374-17-9 (±)-vincadifformine 

Relevant articles and documents

The synthesis of melohenine B and a related natural product

A concise synthesis of melohenine B and O-ethyl-14-epimelohenine B, from eburnamonine, was achieved via a biomimetic diastereoselective singlet oxygen-mediated oxidative cleavage of the indole C2-C7 bond. These studies enabled the assignment of the absolute configuration of the natural products. In line with a proposed biosynthetic pathway, the resulting nine-membered ring containing products could be converted to the corresponding quinolones.

Synthesis of 5-[(Pentafluorosulfanyl)methyl]-γ-butyrolactones via a Silver-Promoted Intramolecular Cyclization Reaction

The synthesis of 5-[(pentafluorosulfanyl)methyl]-γ-butyrolactones bearing different substituents at position 3 or 4 is reported. A silver-promoted intramolecular cyclization of substituted 4-chloro-5-(pentafluorosulfanyl)pentanoic acids allows the preparation of the substituted SF5-containing γ-butyrolactones in up to 96 % yield.

Palladium-Catalyzed Regiocontrollable Reductive Heck Reaction of Unactivated Aliphatic Alkenes

A general Pd-catalyzed intermolecular reductive Heck reaction of both terminal and internal unactivated aliphatic alkenes has been first developed. This method affords γ- and δ-arylated alkyl carboxylic acid derivatives in high yields with complete anti-Markovnikov selectivity. Notably, the coupling process is stereoretentive for the alkyl chain. Mechanistically, alkyl palladacycle intermediates stabilized by directing group and ligand, hydride species multigenerated from PS/TFA reductant, are two key factors that successfully promote the reaction and regioselectivity.