15765-08-9Relevant academic research and scientific papers
Synthesis of Exclusively 4-Substituted β-Lactams through the Kinugasa Reaction Utilizing Calcium Carbide
Hosseini, Abolfazl,Schreiner, Peter R.
, p. 3746 - 3749 (2019/05/24)
A new Kinugasa reaction protocol has been elaborated for the one-pot synthesis of 4-substituted β-lactams utilizing calcium carbide and nitrone derivatives. Calcium carbide is thereby activated by TBAF·3H2O in the presence of CuCl/NMI. The ease of synthesis and use of inexpensive chemicals provides rapid access of practical quantities of β-lactams exclusively substituted at position 4.
1,1-Diphosphines and divinylphosphines via base catalyzed hydrophosphination
Coles,Mahon,Webster
, p. 10443 - 10446 (2018/09/21)
A catalytic hydrophosphination route to 1,1-diphosphines is yet to be reported: these narrow bite angle pro-ligands have been used to great effect as ligands in homogeneous catalysis. We herein demonstrate that terminal alkynes readily undergo double hydrophosphination with HPPh2 and catalytic potassium hexamethyldisilazane (KHMDS) to generate 1,1-diphosphines. A change to H2PPh leads to the formation of P,P-divinyl phosphines.
Efficient approach to 4-sulfonamidoquinolines via copper(I)-catalyzed cascade reaction of sulfonyl azides with alkynyl imines
Cheng, Guolin,Cui, Xiuling
, p. 1480 - 1483 (2013/06/26)
A novel and efficient approach to 4-sulfonamidoquinolines via copper-catalyzed cascade reaction of sulfonyl azides with alkynyl imines has been developed in which a 1,3-dipole cycloaddition/ketenimine formation/6π-electrocyclization/[1,3]-H shift cascade
UNSATURATED IMINE COMPOUND AND USE THEREOF FOR PEST CONTROL
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Page/Page column 244, (2009/05/28)
An α, β-unsaturated imine compound of the formula: wherein A represents a phenyl group or the like, where said aromatic hetero ring forms a carbon-to-carbon bond with a main chain of the compound, R represents a hydrogen atom or a C1 to C5 alkyl group opt
Facile Synthesis of Ethynylated Benzoic Acid Derivatives and Aromatic Compounds via Ethynyltrimethylsilane
Austin, William B.,Bilow, Norman,Kelleghan, William J.,Lau, Kreisler S. Y.
, p. 2280 - 2286 (2007/10/02)
The coupling reaction between an aromatic halide and ethynyltrimethylsilane under the catalysis of palladium(0) generated in situ, followed by treatment of the (trimethylsilyl)ethynyl product with potassium carbonate in methanol at ambient temperatures, provides a simple approach to various ethynylated benzoic acid derivatives and other aromatic compounds.The conditions for the removal of the trimethylsilyl group were very mild, so that base-sensitive functionalities on the aromatic moiety could be tolerated.
