157790-73-3

Upstream product

• 621-59-0 isovanillin 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 17763-80-3 para-nitrophenyl triflate 
• 4885-02-3 Dichloromethyl methyl ether 
• 59099-58-0 2-methoxyphenyl triflate 

Downstream Products

• 160625-50-3 4-methoxy-3-(3-hydroxy-3-methyl-1-butynyl)benzaldehyde 
• 443776-91-8 [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanol 
• 38493-59-3 (3-bromo-4-methoxy-phenyl)-methanol 
• 31825-29-3 3‐isopropyl‐4‐methoxybenzaldehyde 
• 160625-54-7 4-methoxy-3-(3-methyl-3-buten-1-ynyl)acetophenone 
• 160625-53-6 1-<4-methoxy-3-(3-methyl-3-buten-1-ynyl)phenyl>ethanol 
• 160625-49-0 3-ethynyl-4-methoxybenzaldehyde 
• 121007-15-6 4-methoxy-3-(3'-methylbut-3'-en-1'-ynyl)benzyl alcohol 
• 121007-18-9 4-methoxy-3-(3'-methylbut-3'-en-1'-ynyl)benzaldehyde 
• 10035-16-2 benzofuran-5-carbaldehyde 
• 3015-20-1 dehydrotremetone 
• 31823-05-9 5-hydroxymethylbenzo[b]furan 
• 4383-06-6 3-hydroxy-4-methoxybenzyl alcohol 
• 160625-48-9 4-methoxy-3-[2-(trimethylsilyl)ethynyl]benzaldehyde 

Relevant academic research and scientific papers

The reaction of aryl triflates and aryl pivalates with electrophiles. The triflate as a meta-directing group

Electrophilic reactions of substituted aryl triflates yield products wherein the substituents direct the regioselectivity of electrophilic substitution.

Directed ortho Metalation (D o M)-Linked Corriu-Kumada, Negishi, and Suzuki-Miyaura Cross-Coupling Protocols: A Comparative Study

A systematic study of the widely used, titled name reaction transition-metal-catalyzed cross-coupling reactions with attention to context with the directed ortho metalation (D o M) is reported. In general, the Suzuki-Miyaura and Negishi protocols show gre

Efficient cross-coupling of aryl/alkenyl triflates with acyclic secondary alkylboronic acids

Aryl-secondary alkyl cross-coupling with aryl sulfonate esters as coupling partners remains a significant challenge. Efficient cross-coupling between aryl/alkenyl triflates and acyclic secondary alkylboronic acids is realized for the first time to provide a series of sterically congested acyclic secondary alkyl arenes/olefins in good to excellent yields. The employment of sterically bulky P,PO ligand L1/L2 is crucial for the high yields and selectivities. The method has enabled a concise and 4-step synthesis of a key intermediate of male contraceptive agent and PAF antagonist gossypol.

The conversion of phenols to the corresponding aryl halides under mild conditions

Mild, novel procedures have been developed for the syntheses of aryl halides from the corresponding phenols in modest to good yields via boronate ester intermediates.

A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD)

A rapid synthesis of aryl triflate and aryl nonaflate was developed using 4-nitrophenyl triflate and 4-nitrophenyl nonaflate as perfluoroalkanesulfonyl transfer reagents in combination with a polymer supported base (PTBD). Simple filtration of the reactio

An Alternative Route to a Benzofuran Natural Product Dehydrotremetone

Dehydrotremetone, a toxic ketone isolated from the weeds Eupatorium urticaefolium and Aplopappus heterophyllus, has been synthesized from isovanillin via palladium-mediated cross-coupling reaction and lithium chloride-mediated concurrent demethylation-ben