158042-17-2

Basic information

• Product Name: 3,5-bis(4-chlorophenyl)-1,2,4-oxadiazole
• Synonyms: 3,5-bis(4-chlorophenyl)-1,2,4-oxadiazole
• CAS NO: 158042-17-2
• Molecular Formula: C14H8Cl2N2O
• Molecular Weight: 291.13212
• Mol File: 158042-17-2.mol
• Article Data: 13

Chemical Properties

• Melting Point: 183 °C(Solv: ethanol (64-17-5))
• Boiling Point: 425.9±55.0 °C(Predicted)
• Appearance: /
• Density: 1.365±0.06 g/cm3(Predicted)
• PKA: -2.29±0.37(Predicted)
• CAS DataBase Reference: 3,5-bis(4-chlorophenyl)-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(4-chlorophenyl)-1,2,4-oxadiazole(158042-17-2)
• EPA Substance Registry System: 3,5-bis(4-chlorophenyl)-1,2,4-oxadiazole(158042-17-2)

Safety Data

• Hazardous Substances Data: 158042-17-2(Hazardous Substances Data)

Upstream product

• 3717-24-6 4-chlorobenzaldehyde oxime 
• 68451-85-4 C₁₄H₁₀Cl₂N₂O₂ 
• 5033-28-3 4-chlorobenzamidoxime 
• 104-88-1 4-chlorobenzaldehyde 
• 622-95-7 4-chlorobenzyl bromide 
• 3848-36-0 4-chlorobenzaldoxime 
• 623-03-0 4-Cyanochlorobenzene 
• 122-01-0 4-chloro-benzoyl chloride 
• 108-30-5 succinic acid anhydride 
• 74903-80-3 (Z)-N-hydroxy-4-chloro-benzenecarboximidoyl chloride 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 188118-38-9 4-Chloro-N,N-diethyl-N'-hydroxy-benzamidine 
• 74-11-3 para-chlorobenzoic acid 
• 5033-28-3 4-chloro-N'-hydroxybenzimidamide 

Relevant articles and documents

Imidazole hydrochloride promoted synthesis of 3,5-disubstituted-1,2,4-oxadiazoles

Imidazole hydrochloride as an additive promotes the reaction of amidoximes and DMA derivatives to generated 3,5-disubstituted-1,2,4-oxadiazoles in low to excellent yields without the use of coupling reagents, oxidants, strong acids or bases and other additives.

An efficient method for the one-pot tandem synthesis of 3,5-disubstituted-1,2,4-oxadiazoles from benzyl halides

The first example of a one-pot tandem approach for the synthesis of 3,5-disubstituted-1,2,4-oxadiazole derivatives from benzyl halides and amidoxime is reported. Derivatives of 3,5-disubstituted 1,2,4-oxadiazole were obtained in excellent yields under mil

Mild and efficient one-pot synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from nitriles mediated by K 3PO 4

Potassium phosphate, K3PO4, has been proved to be a cheap, strong, and efficient reagent for the one-pot synthesis of 3,5-disubstituted-1,2,4-oxadiazoles from nitriles and acid chlorides under mild conditions. [Supplementary material