158342-55-3

Upstream product

• 64-17-5 ethanol 
• 158342-58-6 ((1R,6R)-6-Cyanomethyl-cyclohex-3-enyl)-acetonitrile 
• 158342-59-7 Trans-cyclohexene-4,5-diacetic Acid 
• 158342-57-5 trans-4,5-Dihydroxymethyl-cyclohexen-ditosylat 
• 15679-27-3 (4S,5S)-4,5-bis(hydroxymethyl)cyclohexene 

Downstream Products

• 6088-72-8 (1R,6R)-bicyclo<4.3.0>nonan-8-one 
• 158267-49-3 (1R,6S,7R,8S)-7-<(benzyloxy)methyl>bicyclo<4.3.0>nonan-8-amine 
• 158267-47-1 (1R,6S,7S)-7-<(benzyloxy)methyl>bicyclo<4.3.0>non-3-en-8-one 
• 158267-58-4 (1R,6S,7S)-7-<(benzyloxy)methyl>-8,8-(ethylenedioxy)bicyclo<4.3.0>non-3-ene 
• 158267-55-1 (1R,6S,7R,8S)-N-(tert-butoxycarbonyl)-7-<(benzyloxy)methyl>bicyclo<4.3.0>nonan-8-amide 
• 158267-59-5 (1R,6S,7R,8S)-N-(trifluoromethanesulfonyl)-7-<(benzyloxy)methyl>bicyclo<4.3.0>nonan-8-amide 
• 158267-50-6 N,N'-bis<(1R,6S,7R,8S)-7-<(benzyloxy)methyl>bicyclo<4.3.0>non-8-yl>-N,N'-bis(trifluoromethanesulfonyl)-1,3-propanediamide 
• 158267-48-2 (1R,6S,7R,8S)-N-benzyl-7-<(benzyloxy)methyl>bicyclo<4.3.0>non-3-en-8-amine 
• 173737-52-5 (1R,6S,7R,8S)-N-(toluene-4-sulfonyl)-7-<(benzyloxy)methyl>bicyclo<4.3.0>nonan-8-amide 
• 173737-44-5 N,N'-bis<(1R,6S,7R,8S)-7-<(benzyloxy)methyl>bicyclo<4.3.0>non-8-yl>-1,3-propanediamide 
• 173737-45-6 N,N'-bis<(1R,6S,7R,8S)-7-(hydroxymethyl)bicyclo<4.3.0>non-8-yl>-N,N'-bis(toluene-4-sulfonyl)-1,3-propanediamide 
• 173737-54-7 N,N'-bis<(1R,6S,7R,8S)-7-formylbicyclo<4.3.0>non-8-yl>-N,N'-bis(toluene-4-sulfonyl)-1,3-propanediamide 
• 173737-46-7 N,N'-bis<(1R,6S,7S,8S)-7-((E)-1-iodo-2-ethenyl)bicyclo<4.3.0>-8-nonyl>-N,N'-bis(toluene-4-sulfonyl)-1,3-propanediamide 
• 173737-53-6 N,N'-bis<(1R,6S,7R,8S)-7-<(benzyloxy)methyl>bicyclo<4.3.0>non-8-yl>-N,N'-bis(toluene-4-sulfonyl)-1,3-propanediamide 

Relevant academic research and scientific papers

Methods of treating disease through the administration of a manzamine analog or derivative

A method of treating cancer, inflammatory disease or an infectious disease or condition in a subject in need of such treatment is disclosed. The method comprises administering to a subject an effective amount of a manzamine, or a rationally modified manzamine derivative or analog or an optical isomer or racemate or tautomer thereof or a pharmaceutically acceptable salt or prodrug thereof generated through optimized fermentation of a Micromonospora sp., extraction from sponges and then modified through semisynthesis.

Total synthesis of (+)-papuamine: An antifungal pentacyclic alkaloid from a marine sponge, Haliclona sp.

The total synthesis of (+)-papuamine, the antipode of the C2-symmetric, optically active, pentacyclic diamine natural product, starting from a chiral diol is described. The diol is available via an asymmetric Diels-Alder reaction between 1,3-bu

Total Synthesis of (+)-Papuamine: Determination of the Absolute Stereochemistry of the Natural Product

The total synthesis of (+)-papuamine has been completed using an intramolecular Pd0 catalysed (Stille) coupling reaction to close the central diazadiene macrocycle unit.