158342-59-7Relevant articles and documents
Methods of treating disease through the administration of a manzamine analog or derivative
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Page/Page column 12, (2008/06/13)
A method of treating cancer, inflammatory disease or an infectious disease or condition in a subject in need of such treatment is disclosed. The method comprises administering to a subject an effective amount of a manzamine, or a rationally modified manzamine derivative or analog or an optical isomer or racemate or tautomer thereof or a pharmaceutically acceptable salt or prodrug thereof generated through optimized fermentation of a Micromonospora sp., extraction from sponges and then modified through semisynthesis.