6947-04-2

Upstream product

• 75-03-6 ethyl iodide 
• 911793-49-2 3,3-ethylenedioxycyclopentanecarboxylic acid 
• 930-30-3 cyclopent-2-enone 
• 41171-91-9 3-oxocyclopentane-1-carbonitrile 
• 159329-38-1 3,3-ethylenedioxycyclopentanecarbonitrile 
• 98-78-2 3-Oxo-cyclopentanecarboxylic acid 
• 107-21-1 ethylene glycol 
• 5400-79-3 ethyl 3-oxocyclopentanecarboxylate 

Downstream Products

• 77250-35-2 C₂₁H₂₂N₂O₄ 
• 1363382-39-1 tert-butyl 6-oxo-2-azaspiro [3.4] octane-2-carboxylate 

Relevant academic research and scientific papers

Facile synthesis of 2-azaspiro[3.4]octane

Our annulation strategy utilized for the synthesis of 2-azaspiro[3.4]octane is explained. Three successful routes for the synthesis were developed. One of the approaches involved annulation of the cyclopentane ring and the remaining two approaches involved annulation of the four membered ring. All three approaches employ readily available starting materials with conventional chemical transformations and minimal chromatographic purifications to afford the title compound. The merits and limitations of the three approaches are also discussed.

A containing shuanghuan base [2, 2, 1] and iieptanes of application

The invention relates to compounds capable of being used as a liquid crystal dielectric component, and a preparation method and application thereof. The compounds have a structural general formula (I) as shown in the specification. After adding the compounds disclosed as the structural general formula (I), the liquid crystal composition has the advantages of shorter response time, moderate DELTAn value, higher charge retentivity, lower threshold voltage and wide application prospects.

PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS

The invention relates to compounds of the formula 1, wherein R1, R2, R3, R4, R5, R6, R7, A and B are as defined herein, the pharmaceutical compositions and the uses as pharmaceuticals.

NOVEL COMPOUNDS-300

Compounds of Formula I, or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4, m, n, q, s, t, X, and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Synthesis of bridgehead-substituted bicyclo[2.2.1]heptanes. Radical cyclization of an oxime ether and an α,β-unsaturated ester

The synthesis of bicyclo[2.2.1]heptanes with useful functionality at each bridgehead is achieved by radical cyclization of appropriately substituted 4-methylene- and 4-benzyloxyiminocyclohexylmethyl radicals. The latter process, for example, leads to a br