6947-04-2Relevant articles and documents
Facile synthesis of 2-azaspiro[3.4]octane
Ramesh, Subbiah,Balakumar, Ramadas,Rizzo, John R.,Zhang, Tony Y.
, p. 3056 - 3065 (2019/03/21)
Our annulation strategy utilized for the synthesis of 2-azaspiro[3.4]octane is explained. Three successful routes for the synthesis were developed. One of the approaches involved annulation of the cyclopentane ring and the remaining two approaches involved annulation of the four membered ring. All three approaches employ readily available starting materials with conventional chemical transformations and minimal chromatographic purifications to afford the title compound. The merits and limitations of the three approaches are also discussed.
PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS
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Page/Page column 44; 45, (2010/01/31)
The invention relates to compounds of the formula 1, wherein R1, R2, R3, R4, R5, R6, R7, A and B are as defined herein, the pharmaceutical compositions and the uses as pharmaceuticals.
Synthesis of bridgehead-substituted bicyclo[2.2.1]heptanes. Radical cyclization of an oxime ether and an α,β-unsaturated ester
Della,Knill
, p. 1833 - 1841 (2007/10/02)
The synthesis of bicyclo[2.2.1]heptanes with useful functionality at each bridgehead is achieved by radical cyclization of appropriately substituted 4-methylene- and 4-benzyloxyiminocyclohexylmethyl radicals. The latter process, for example, leads to a br
