160056-33-7Relevant articles and documents
Synthesis and resolution of dinucleotide(TpAZT) phosphoramidates
Lin, Changxue,Fu, Hua,Tu, Guangzhong,Zhao, Yufen
, p. 2553 - 2562 (2007/10/03)
Dinucleotide (TpAZT) phosphoramidates were synthesized through Atherton-Todd reaction of dinucleoside H-phosphonates and amino acid methyl esters, and their diastereomers (Rp and Spu) were separated by crystallization. It was showed that the cheap methyl esters of natural alanine and phenylalanine could act as new chiral auxiliaries for large-scale synthesis of dinucleotide analogs.
Aryl H-phosphonates. Part 11. Synthetic and 31P NMR studies on the formation of aryl nucleoside H-phosphonates
Cieslak, Jacek,Szymczak, Marzena,Wenska, Malgorzata,Stawinski, Jacek,Kraszewski, Adam
, p. 3327 - 3331 (2007/10/03)
The formation of aryl H-phosphonate diesters from the corresponding nucleoside 3′-H-phosphonates and various phenols was investigated in detail using 31P NMR spectroscopy. The major reaction pathways of aryl nucleoside H-phosphonates under diff
Aryl H-phosphonates. 8. Simple and efficient method for the preparation of nucleoside B-phosphonothioate monoesters
Kers, Inger,Kers, Annika,Stawinski, Jacek,Kraszewski, Adam
, p. 3945 - 3948 (2007/10/03)
An efficient method for the preparation of nucleoside 3'-H- phosphonothioate monoesters was developed. It consists of phosphonylation of suitably protected nucleosides with diphenyl H-phosphonate to produce nucleoside phenyl H-phosphonates, followed by th