160056-33-7

Upstream product

• 4712-55-4 diphenyl hydrogen phosphite 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 50571-26-1 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 
• 108-95-2 phenol 
• 3868-27-7 triethylammonium 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 

Downstream Products

• 3868-27-7 triethylammonium 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 
• 50571-26-1 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 
• 57538-74-6 phenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphate 
• 637014-44-9 C₄₁H₄₄N₇O₁₂P 
• 1053633-87-6 C₄₅H₅₁N₈O₁₄P 
• 1055039-22-9 C₄₇H₅₅N₈O₁₄P 
• 1053706-19-6 C₄₈H₅₇N₈O₁₄P 
• 1053647-07-6 C₅₁H₅₅N₈O₁₄P 

Relevant academic research and scientific papers

Synthesis and resolution of dinucleotide(TpAZT) phosphoramidates

Dinucleotide (TpAZT) phosphoramidates were synthesized through Atherton-Todd reaction of dinucleoside H-phosphonates and amino acid methyl esters, and their diastereomers (Rp and Spu) were separated by crystallization. It was showed that the cheap methyl esters of natural alanine and phenylalanine could act as new chiral auxiliaries for large-scale synthesis of dinucleotide analogs.

Aryl H-phosphonates. Part 13. A new, general entry to aryl nucleoside phosphate and aryl nucleoside phosphorothioate diesters

The reaction of nucleoside H-phosphonate monoesters with phenols in the presence of a condensing agent, followed by oxidation of the in-situ-generated aryl nucleoside H-phosphonate diesters with iodine-water or with elemental sulfur, provides a new, 'one-

Aryl H-phosphonates. Part 11. Synthetic and 31P NMR studies on the formation of aryl nucleoside H-phosphonates

The formation of aryl H-phosphonate diesters from the corresponding nucleoside 3′-H-phosphonates and various phenols was investigated in detail using 31P NMR spectroscopy. The major reaction pathways of aryl nucleoside H-phosphonates under diff

31p NMR studies on oxidative transformations of aryl nucleoside h-phosphonate diesters

Various aspects of oxidative coupling of nucleoside aryl H-phosphonate diesters with nucleosides to produce important synthetic intermediates in the phosphotriester approach to oligonucleotide synthesis, dinucleoside aryl phosphotriesters, was investigated. Copyright

Aryl H-phosphonates. 8. Simple and efficient method for the preparation of nucleoside B-phosphonothioate monoesters

An efficient method for the preparation of nucleoside 3'-H- phosphonothioate monoesters was developed. It consists of phosphonylation of suitably protected nucleosides with diphenyl H-phosphonate to produce nucleoside phenyl H-phosphonates, followed by th

Studies on aryl H-phosphonates. I. An efficient method for the preparation of deoxyribo- and ribonucleoside 3'-H-phosphonate monoesters by transesterification of diphenyl H-phosphonate

A convenient method for the preparation of deoxyribonucleoside and ribonucleoside 3'-H-phosphonate monoesters via transesterification of diphenyl H-phosphonate with suitable protected nucleosides in pyridine is described.