160115-23-1Relevant articles and documents
Aluminium - SALEN complex: a new catalyst for the enantioselective Michael reaction
Iha, S. C.,Joshi, N. N.
, p. 2463 - 2466 (2001)
A new heterobimetallic complex prepared from a chiral SALEN ligand and Red-Al(R) was found to catalyse the Michael reaction between various dialkyl malonates and cycloalkenones to give products in high yields with e.e. of up to 58 percent.
Asymmetric Michael reactions of α-substituted acetates with cyclic enones catalyzed by multifunctional chiral Ru amido complexes
Ikariya, Takao,Wang, Hui,Watanabe, Masahito,Murata, Kunihiko
, p. 1377 - 1381 (2004)
Well-defined 16-electron chiral Ru amido complexes, Ru[(R,R)-diamine](η6-arene), efficiently catalyze asymmetric Michael additions of Michael donors to cyclic enones to give adducts in high yields and with excellent ee's. β-Ketoesters or nitroa
Asymmetric michael addition of dimethyl malonate to 2-cyclopenten-1-one catalyzed by a heterobimetallic complex
Fastuca, Nicholas J.,Wong, Alice R.,Mak, Victor W.,Reisman, Sarah E.
, p. 327 - 338 (2021/04/05)
A. Preparation of GaNa-(S)-BINOL((S)-2) Solution (0.05 M).2 A flame-dried 1L, three-necked round-bottomed flask with 24/40 joints and a 1.5 Teflon coated egg-shaped magnetic stir bar is brought into a nitrogen filled glovebox (Note 2). The flask is charged with gallium (III) chloride (5.0 g, 28.4 mmol, 1.0 equiv) (Notes 3 and 4). The flask is sealed with three rubber septa (one of which is fitted with an internal temperature probe) brought out of the glovebox, and put under positive pressure of nitrogen via a needle attached to a nitrogen line. Another flame-dried 1L, three-necked round-bottomed flask with 24/40 joints and a 1.5 Teflon coated egg-shaped magnetic stir bar is charged with (S)-(-)-1,1'-bi(2-naphthol) ((S)-BINOL, (S)-1) (16.26 g, 56.8 mmol, 2.0 equiv) (Note 5). The flask is sealed with three rubber septa (one of which is fitted with a thermometer) and evacuated and backfilled with nitrogen three times (5 minutes under vacuum per cycle). A flame-dried 500 mL round-bottomed flask with a 24/40 joint and a 1 Teflon coated egg-shaped magnetic stir bar is charged with sodium tert -butoxide (10.92 g, 113.6 mmol, 4.0 equiv) (Note 6). The flask is sealed with a rubber septum and evacuated and backfilled with nitrogen three times (5 minutes under vacuum per cycle).
Mapping the Surface Groups of Amine-Rich Carbon Dots Enables Covalent Catalysis in Aqueous Media
Amato, Francesco,Bonchio, Marcella,Companyó, Xavier,Dell'Amico, Luca,Filippini, Giacomo,Prato, Maurizio,Ragazzon, Giulio,Rosso, Cristian,Vega-Pe?aloza, Alberto
supporting information, p. 3022 - 3037 (2020/11/03)
Carbon nanodots stand as the missing link between the molecular and the nanoscale world, owing to the unique molecular-like behavior emerging from their synthetic precursors. A converging set of analytical and spectroscopic data yields a precise inventory
Enzyme-Promoted Direct Asymmetric Michael Reaction by Using Protease from Streptomyces griseus
Wu, Ling-Ling,Li, Ling-Po,Xiang, Yang,Guan, Zhi,He, Yan-Hong
, p. 2209 - 2214 (2017/07/24)
The direct asymmetric Michael addition of malonates and enones was promoted by protease from Streptomyces griseus for the first time. Yields of up to 84% with enantioselectivities of up to 98% enantiomeric excess (ee) were achieved under optimized conditi
