16017-63-3 Usage
Description
2-[4-(phenylsulfonyl)piperazino]-1-ethanol, also known as PF-8380, is a piperazine derivative featuring a phenylsulfonyl group and an ethanol moiety. This chemical compound has garnered interest due to its potential neuroprotective properties and its capacity to modulate neurotransmitter systems within the central nervous system. PF-8380's pharmacological attributes position it as a promising candidate for the treatment of neurodegenerative conditions, warranting further exploration and development in the realm of neurological therapeutics.
Uses
Used in Pharmaceutical Industry:
2-[4-(phenylsulfonyl)piperazino]-1-ethanol is used as a neuroprotective agent for its potential to shield neurons from damage and degeneration, particularly in the context of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Its neuroprotective effects are attributed to its ability to modulate neurotransmitter systems, thereby potentially slowing disease progression and improving patient outcomes.
Used in Research and Development:
In the field of pharmaceutical research and development, 2-[4-(phenylsulfonyl)piperazino]-1-ethanol serves as a subject of preclinical studies aimed at understanding its mechanisms of action and efficacy. 2-[4-(phenylsulfonyl)piperazino]-1-ethanol's potential to treat neurological disorders makes it a valuable asset for advancing the discovery of new therapeutic agents and deepening the understanding of neurodegenerative pathophysiology.
Check Digit Verification of cas no
The CAS Registry Mumber 16017-63-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,1 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16017-63:
(7*1)+(6*6)+(5*0)+(4*1)+(3*7)+(2*6)+(1*3)=83
83 % 10 = 3
So 16017-63-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O3S/c15-11-10-13-6-8-14(9-7-13)18(16,17)12-4-2-1-3-5-12/h1-5,15H,6-11H2
16017-63-3Relevant articles and documents
C-3 NOVEL TRITERPENE WITH C-17 AMINE DERIVATIVES AS HIV INHIBITORS
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Page/Page column 38, (2017/09/15)
The present invention relates to to C-3 novel triterpene with C-17 amine derivatives of formula (I); or pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, R4, R5 and 'n' are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) and process for preparing them, and their use for the treatment of viral diseases and particularly HIV mediated diseases.