1606-01-5

Basic information

• Product Name: DIETHYLGLYCINE HYDROCHLORIDE
• Synonyms: DIETHYLGLYCINE HYDROCHLORIDE;Diethylamino-acetic acid hydrochloride;Diethylglycine hydrochloride ,98.5%;glycine, N,N-diethyl-;2-(diethylamino)acetic acid hydrochloride;2-(diethylamino)ethanoic acid;N,N-diethylglycine(SALTDATA: HCl);N,N-DiethylaMinoacetic acid
• CAS NO: 1606-01-5
• Molecular Formula: C₆H₁₃NO₂
• Molecular Weight: 167.63
• EINECS: 216-520-8
• Mol File: 1606-01-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: 126-130 °C
• Boiling Point: 203.2 °C at 760 mmHg
• Flash Point: 76.7 °C
• Appearance: /
• Density: 1.013 g/cm³
• Vapor Pressure: 0.116mmHg at 25°C
• PKA: 2.34±0.10(Predicted)
• CAS DataBase Reference: DIETHYLGLYCINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLGLYCINE HYDROCHLORIDE(1606-01-5)
• EPA Substance Registry System: DIETHYLGLYCINE HYDROCHLORIDE(1606-01-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 1606-01-5(Hazardous Substances Data)

Usage

General Description

DIETHYLGLYCINE HYDROCHLORIDE is a chemical compound with the molecular formula C6H14ClNO2. It is a salt formed by diethylglycine, an amino acid derivative, and hydrochloric acid. DIETHYLGLYCINE HYDROCHLORIDE has potential applications in the pharmaceutical industry, particularly in the development of drugs for the treatment of neurological disorders and as a building block for the synthesis of novel organic compounds. It is also used as a reagent in chemical synthesis and as a chelating agent in analytical chemistry. Additionally, diethylglycine hydrochloride is known for its ability to improve the solubility and bioavailability of poorly water-soluble drugs, making it a valuable additive in drug formulations.

InChI:InChI=1/C6H13NO2.ClH/c1-3-7(4-2)5-6(8)9;/h3-5H2,1-2H3,(H,8,9);1H

Upstream product

• 2644-21-5 ethyl N,N-diethylglycinate 
• 75-07-0 acetaldehyde 
• 56-40-6 glycine 
• 79-08-3 bromoacetic acid 
• 109-89-7 diethylamine 
• 79-11-8 chloroacetic acid 
• 64-67-5 diethyl sulfate 
• 64-17-5 ethanol 
• 592-41-6 1-hexene 
• 816-43-3 lithium diethylamide 
• 64916-53-6 bromoacetic acid lithium salt 
• 19326-51-3 chloroacetic acid lithium salt 
• 5426-55-1 N,N-diethylglycine sodium salt 

Downstream Products

• 1253960-43-8 1-(4-(4-amino-5-(4-(3,4-dichlorophenoxy)-3-methoxyphenyl)-6-(3-(pyrrolidin-1-yl)propyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)piperidin-1-yl)-2-(diethylamino)ethanone 
• 74816-21-0 2-diethylamino-N-(4-nitro-phenyl)-acetamide 
• 84570-77-4 Triethyl-[(4-nitro-phenylcarbamoyl)-methyl]-ammonium; chloride 
• 1443470-24-3 C₃₀H₃₉N₅O₉S 
• 1268165-43-0 [[(N,N-diethylglycine(-H))2Sn(CH₂C₆H₄)2] 
• 1262439-57-5 2-(diethylamino)-N-((1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazol-4-yl)methyl)ethanamide 
• 1262439-55-3 N-((1-(2-bromophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(diethylamino)ethanamide 
• 1262439-53-1 2-(diethylamino)-N-((1-(4-methoxy-2-nitrophenyl)-1H-1,2,3-triazol-4-yl)methyl)ethanamide 
• 1262439-51-9 2-(diethylamino)-N-((1-(2,4,6-trichlorophenyl)-1H-1,2,3-triazol-4-yl)methyl)ethanamide 
• 1262439-50-8 2-(diethylamino)-N-((1-(2,4,6-tribromophenyl)-1H-1,2,3-triazol-4-yl)methyl)ethanamide 
• 1262439-49-5 N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-2-(diethylamino)ethanamide 
• 1262439-48-4 2-(diethylamino)-N-((1-(3-methoxyphenyl)-1H-1,2,3-triazol-4-yl)methyl)ethanamide 
• 1262439-47-3 N-((1-(3-iodophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(diethylamino)ethanamide 

Relevant articles and documents

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Nitrogen-containing cyclic compounds as iminium ion sources for selected reaction monitoring detection of derivatized analytes

Liquid chromatography–tandem mass spectrometry is one of the most sensitive tools for determination of trace amounts of analytes in metabolomics and proteomics. The highest sensitivity is achieved in selected reaction monitoring detection, which involves fragmentation of the molecular ion between two levels of mass selection. However, fragmentation of some compounds is complicated. Detection sensitivity of such analytes may be increased by derivatizing them with a specific moiety fragmentation of which results in product ion of high abundance. In this work, we reveal the influence of iminium ions' structures on their stability by comparing six nitrogen-containing cyclic compounds as derivatization reagents for tandem mass spectrometric analysis of amino group-containing analyte. Commercially available starting materials (piperidine, 2,6-dimethylpiperidine, 1-methylpiperazine, morpholine, pyrrolidine and 1-cyanomethyl-3-methylimidazolium ionic liquid) were used for the synthesis of corresponding carboxylic acids which were further used for derivatization of the model analyte tryptamine. Liquid chromatographic–mass spectrometric analysis of differently derivatized tryptamine was performed for the evaluation of release and stability of corresponding iminium ions under collision-induced dissociation conditions. As a result, morpholine moiety was shown being the most promising iminium ion source among tested compounds. Possible sub-fragmentation pathways of investigated iminium ions were discussed, and the structures of secondary product ions were proposed.

Method and using tracer charged ion channel

The invention provides compounds, compositions, methods, and kits for the treatment of pain, itch, and neurogenic inflammation.