1607833-80-6

Basic information

• Product Name: 6-methyl-8-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
• Synonyms: 6-methyl-8-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
• CAS NO: 1607833-80-6
• Molecular Weight: 240.261
• Mol File: 1607833-80-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-methyl-8-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-8-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one(1607833-80-6)
• EPA Substance Registry System: 6-methyl-8-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one(1607833-80-6)

Safety Data

• Hazardous Substances Data: 1607833-80-6(Hazardous Substances Data)

Upstream product

• 1607833-75-9 3-amino-6-methyl-4-phenylpyridine-2(1H)-one 
• 1607833-78-2 N-(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)-2-chloroacetamide 
• 89-31-6 rac-salsoline 
• 53912-89-3 (2S)-2-(3-pyridyl)piperidine hydrochloride 
• 15191-27-2 1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one 
• 93-91-4 1-phenylbutan-1,3-dione 
• 79-04-9 chloroacetyl chloride 

Relevant articles and documents

Synthesis of N-Derivatives of Cytisine, Anabasine, and Salsoline Alkaloids with Pharmacophore 3-Aminopyridine-2(1H)-one and 5-Methyl-7-phenyloxazole[5,4-b]pyridine Cycles

The reaction of nucleophilic substitution of 2-chloro-N-(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)acetamide and 2-(chloromethyl)-5-methyl-7-phenyloxazolo[5,4-b]pyridine with cytisine, anabasine, and salsoline alkaloids has afforded the corresponding derivatives. Structure of the obtained compounds has been confirmed by means of 1H and 13C NMR spectroscopy.

Synthesis of 3-aminopyridin-2(1H)-ones and 1H-pyrido[2,3-b][1,4]oxazin- 2(3H)-ones

The interaction of 1,3-diketones with chloroacetamide produced N-(3-oxoalkenyl)chloroacetamides. Heating of N-(3-oxoalkenyl)chloroacetamides with an excess of pyridine in ethanol or butanol led to the formation of pyridin-2(1H)-ones, substituted with a py