1607833-78-2Relevant academic research and scientific papers
Synthesis of N-substituted 2-aminomethyl-5-methyl-7-phenyloxazolo[5,4-b]pyridines
Palamarchuk, Irina V.,Matsukevich, Mariya V.,Kulakov, Ivan V.,Seilkhanov, Tulegen М.,Fisyuk, Aleksander S.
, p. 788 - 791 (2019)
[Figure not available: see fulltext.] 2-(Chloromethyl)-5-methyl-7-phenyloxazolo[5,4-b]pyridine was obtained by intramolecular cyclization based on the previously synthesized 2-chloro-N-(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)acetamide. The possibility of its use in the synthesis of previously unknown 2-aminomethyloxazolo[5,4-b]pyridine derivatives by nucleophilic substitution with various amines and a cyclic amide has been shown.
Synthesis of N-Derivatives of Cytisine, Anabasine, and Salsoline Alkaloids with Pharmacophore 3-Aminopyridine-2(1H)-one and 5-Methyl-7-phenyloxazole[5,4-b]pyridine Cycles
Palamarchuk,Ogurtsova,Seilkhanov,Kulakov
, p. 2487 - 2491 (2020/02/25)
The reaction of nucleophilic substitution of 2-chloro-N-(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)acetamide and 2-(chloromethyl)-5-methyl-7-phenyloxazolo[5,4-b]pyridine with cytisine, anabasine, and salsoline alkaloids has afforded the corresponding derivatives. Structure of the obtained compounds has been confirmed by means of 1H and 13C NMR spectroscopy.
Synthesis of 3-aminopyridin-2(1H)-ones and 1H-pyrido[2,3-b][1,4]oxazin- 2(3H)-ones
Fisyuk,Kulakov,Goncharov,Nikitina,Bogza,Shatsauskas
, p. 217 - 224 (2014/06/23)
The interaction of 1,3-diketones with chloroacetamide produced N-(3-oxoalkenyl)chloroacetamides. Heating of N-(3-oxoalkenyl)chloroacetamides with an excess of pyridine in ethanol or butanol led to the formation of pyridin-2(1H)-ones, substituted with a py
Synthesis of 3-aminopyridin-2(1H)-ones and 1H-pyrido[2,3-b][1,4]oxazin-2(3H)-ones
Fisyuk,Kulakov,Goncharov,Nikitina,Bogza,Shatsauskas
, p. 217 - 224 (2015/09/28)
The interaction of 1,3-diketones with chloroacetamide produced N-(3-oxoalkenyl)chloroacetamides. Heating of N-(3-oxoalkenyl)chloroacetamides with an excess of pyridine in ethanol or butanol led to the formation of pyridin-2(1H)-ones, substituted with a py
