16089-77-3Relevant academic research and scientific papers
Synthesis of 1,2,4-oxadiazolidines via [3+2] cycloaddition of nitrones with carbodiimides
Chen, Yuan,Fuyue, Liuting,Wang, Gangqiang,Wang, Hang,Lu, Chun,Guo, Haibing,St. Amant, Chiara,Sun, Shaofa,Xing, Yalan
supporting information, p. 4329 - 4332 (2019/03/19)
An efficient [3+2] cycloaddition of nitrones and carbodiimides has been developed. This 1,3-dipolar cycloaddition features high regioselectivity, mild and metal-free conditions, excellent functional group compatibility, and a broad substrate scope. The X-ray structures of two regio-isomers confirmed the regioselectivity of this transformation.
A highly diastereoselective [3+3] annulation reaction of aza-oxyallyl cations and nitrones
Chen, Rongxing,Sun, Shaofa,Wang, Gangqiang,Guo, Haibin
supporting information, p. 1916 - 1920 (2018/04/19)
An efficient synthesis of 1,2,4-oxadiazinan-5-ones via [3+3] cycloaddition of in situ generated aza-oxyallyl cations with nitrones has been developed. The protocol features easy operation, excellent yields, excellent diastereo-control, broad substrate sco
1,3-Dipolar cycloadditions. Part-XV: Systematic spectroscopic investigations of C-aryl-N-methylnitrones
Banerji, Avijit,Acharjee, Nivedita,Biswas, Pizush Kanti
scheme or table, p. 63 - 67 (2010/05/02)
Several C-aryl-N-methylnitrones have been synthesised during the course of our work on 1,3-dipolar cycloadditions. Detailed systematic spectroscopic investigations of all these nitrones have been undertaken. These are reported along with some generalisati
1,3-Dipolar cycloadditions: Part VIII1-Microwave irradiation assisted synthesis of N-methyl-C-aryl nitrones
Banerji, Avijit,Biswas, Pizush Kanti,Sengupta, Piyali,Dasgupta, Saugandha,Gupta, Maya
, p. 880 - 881 (2007/10/03)
N-Methyl-C-arylnitrones have been synthesized in very high yields within a few minutes from N-methyl-hydroxylamine hydrochloride and aryl aldehydes in presence of sodium hydrogen carbonate in methylene chloride using the microwave irradiation technique.
A facile and new method for the synthesis of α-aryl-N-methylnitrones in solvent-free media using silica gel-NaOH
Alavi Nikje,Bigdeli,Imanieh
, p. 1465 - 1468 (2007/10/03)
Substituted α-aryl-N-methylnitrones are prepared by the condensation reaction of N-methylhydroxylamine hydrochloride and benzaldehydes in solvent-free media using silica-gel-NaOH catalyst system. The yields are excellent regardless of the electron-donatin
An efficient and rapid chemoselective synthesis of α-Aryl-N-methylnitrones in dry media
Bigdeli,Nikje
, p. 1547 - 1549 (2007/10/03)
A simple, efficient, and eco-friendly procedure was developed for the condensation of N-methylhydroxylamine hydrochloride with benzaldehydes bearing electron-donating or electron-withdrawing substituents in the presence of powdered molecular sieves (3 A)
Oxidation of N-benzyl-N-methylhydroxylamines to nitrones. A mechanistic study
Hassan, Azfar,Wazeer, Mohammed I. M.,Ali, Sk. Asrof
, p. 393 - 399 (2007/10/03)
Oxidation of various N-(o-, m-, p- substituted benzyl)- N-methylhydroxylamines has been carried out using mercury(II) oxide and p-benzoquinone (p-BQ) as oxidants. Hammett plots have been obtained with negative ρ values, showing the development of a positive centre in the transition state. The unstable E nitrones, which readily isomerize to the more stable Z nitrones, are obtained in appreciable quantities and in some cases as the major product. A considerable deuterium isotope effect is observed in the oxidation process. The overall picture of the mechanistic pathway involves electron transfer from nitrogen to the oxidant followed by hydrogen abstraction.
