1614-73-9

Basic information

• Product Name: cyclohept-4-ene-1-carboxylic acid
• CAS NO: 1614-73-9
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.1797
• Mol File: 1614-73-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 257.4°C at 760 mmHg
• Flash Point: 118.9°C
• Density: 1.08g/cm³
• Vapor Pressure: 0.00444mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: cyclohept-4-ene-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cyclohept-4-ene-1-carboxylic acid(1614-73-9)
• EPA Substance Registry System: cyclohept-4-ene-1-carboxylic acid(1614-73-9)

Safety Data

• Hazardous Substances Data: 1614-73-9(Hazardous Substances Data)

Usage

Description

Cyclohept-4-ene-1-carboxylic acid is a bicyclic organic compound characterized by its molecular formula C8H12O2. It features a seven-membered ring with a carboxylic acid functional group attached to one of the carbon atoms. cyclohept-4-ene-1-carboxylic acid is recognized for its reactivity in a variety of chemical reactions and its unique molecular structure, which makes it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, as well as in the development of new compounds with potential biological and industrial applications.

Uses

Used in Organic Synthesis:
Cyclohept-4-ene-1-carboxylic acid is utilized as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its reactivity and structural features facilitate the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, cyclohept-4-ene-1-carboxylic acid serves as a building block for the development of new drugs. Its unique structure and reactivity contribute to the design of novel therapeutic agents with potential applications in treating various diseases and conditions.
Used in Agrochemical Industry:
Cyclohept-4-ene-1-carboxylic acid is also employed in the agrochemical sector as a precursor for the synthesis of various agrochemicals. Its role in this industry is crucial for the development of new pesticides, herbicides, and other agricultural chemicals that can improve crop yields and protect plants from pests and diseases.
Used in Fine Chemicals Production:
cyclohept-4-ene-1-carboxylic acid is used as a starting material in the production of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, dyes, and specialty chemicals. Its unique properties make it suitable for the synthesis of high-value products in this industry.

Upstream product

• 5473-11-0 2-(N-pyrrolidinyl)bicyclo<3.2.1>octan-8-one 
• 74-88-4 methyl iodide 
• 2401-88-9 4-cycloheptenecarboxaldehyde 
• 138619-95-1 2-chloro-5-cycloocten-1-one 
• 120-92-3 cyclopentanone 
• 4840-12-4 N,N-dimethyl-1-cyclopenten-1-amine 
• 107-02-8 acrolein 
• 825-61-6 2-chloro-5-cycloocten-1-one oxime 

Downstream Products

• 51175-18-9 1-(1-Hydroxy-cyclohexyl)-cyclohept-4-enecarboxylic acid 
• 55679-31-7 Bicyclo<3.2.1>-octan-8-on 
• 4448-75-3 cycloheptylmethanol 
• 6729-41-5 4-Brom-benzolsulfonsaeure-<1-methyl-cyclohepten-(4)-yl-methylester> 
• 6221-55-2 bicyclo[3.2.1]octane 
• 122709-69-7 2-[2-Benzenesulfonyl-2-(pyridin-2-ylsulfanyl)-ethyl]-8-methyl-8-aza-bicyclo[3.2.1]octane 
• 529-17-9 tropane 
• 130837-60-4 2-(4'-cyclohepten-1'-yl)-2-keto-1-triphenylphosphazino-ethane 
• 19686-79-4 cyclohept-4-en-1-one 
• 872164-44-8 N-(phenylthio)cyclohept-4-enecarboxamide 
• 1460-16-8 cycloheptanoic acid 
• 63048-50-0 (1α,4α,5α)-4-(phenylseleno)-6-oxabicyclo<3.2.2>nonan-7-one 

Relevant articles and documents

Thermal Rearrangement of 3-Methylenespirododeca-1,4,9-triene and Spirododeca-1,4,9-trien-3-one

Introduction of a double bond into the seven-membered ring of 3-methylenespirododeca-1,4-dien-3-one (1) or spirododeca-1,4-diene (16) alters the thermal behavior of both compounds.Pyrolysis of 3-methylenespirododeca-1,4,9-triene (5) affords the isomeric hydrocarbon cis,cis-2,5-dimethylene-7-vinylbicyclonon-3-ene (11).Pyrolysis of the related ketone spirododeca-1,4,9-trien-3-one (6) gives a mixture of cis,cis-5-methylene-9-vinylbicyclo-3-nonen-2-one (21), cis,cis-5-methylene-7-vinylbicyclo-3-nonen-2-one (22), and trans,trans-2,4,5a,6,8a,8b-hexahydroacenaphthylen-5(1H)-one (23).Mechanistic rationales for these reactions are presented.

13C-1H Coupling Constants in Carbocations. 5. Trishomocyclopropenium Cations Generated from Bicyclohex-3-yl, Tricyclo2,4>oct-8-yl, and Pentacyclo2,4.03,8.05,7>non-9-yl Precursors

One-bond 13C-H coupling constants have been measured for the trismonocyclopropenium cations derived from bicyclohex-3-yl (1), tricyclo2,4>oct-8-yl, (12, 14) and pentacyclo2,4.03,8.05,7>non-9-yl (26, 27) precursors under stable ion conditions and compared with those of the corresponding model ketones. the ΔJ values thus obtained for the bridging carbons (21-32Hz) and the ajacent methylene or methine carbons (18-27 Hz) are large and not consistent with static or equilibrating classical structures for these cations.The data provide additional confirmation of the ??-bridged, nonclassical nature of these

GENERAL APPROACH FOR THE SYNTHESIS OF POLYQUINENES VIA THE WEISS REACTION XIII. ALDOL APPROACH TO FENESTRANES

The acid-catalyzed intramolecular aldol cyclization (HCl/THF; Ac2O) of diketodialdehyde 5 under conditions of thermodynamic (equilibration) control furnished the 8α,12β-diacetoxytetracyclo4,13.010,13>tridecane-2,6-dione 6 to

AN IMPROVED SYNTHESIS OF 4-CYCLOHEPTENE-1-CARBOXYLIC ACID

Modification of the method of Stork and Landesman (J.Am.Chem.Soc. 1956, 78, 5129) permitted the synthesis of the title acid (1) in 58 percent yield from a cylopentanone enamine.Acid 1 is a useful intermediate for the preparation of 4-substituted cycloheptenes in good yields.