16156-53-9

Basic information

• Product Name: 2-METHYLPROPYLMETHANESULPHONATE
• Synonyms: 2-METHYLPROPYLMETHANESULPHONATE;METHANESULPHONICACIDISOBUTYLESTER;2-Methylpropyl methanesulfonate;Isobutyl methanesulfonate
• CAS NO: 16156-53-9
• Molecular Formula: C₅H₁₂O₃S
• Molecular Weight: 152.212
• Mol File: 16156-53-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 53°C/1mmHg(lit.)
• Flash Point: 97 °C
• Appearance: /
• Density: 1.096 g/cm³
• Vapor Pressure: 0.0714mmHg at 25°C
• Refractive Index: 1.4230 to 1.4270
• CAS DataBase Reference: 2-METHYLPROPYLMETHANESULPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLPROPYLMETHANESULPHONATE(16156-53-9)
• EPA Substance Registry System: 2-METHYLPROPYLMETHANESULPHONATE(16156-53-9)

Safety Data

• RTECS: PB2662500
• Hazardous Substances Data: 16156-53-9(Hazardous Substances Data)

Usage

General Description

2-Methylpropylmethanesulphonate is a chemical compound with the formula C5H12O3S. It is a clear, colorless liquid that is soluble in water and commonly used as a reagent in organic synthesis. It is often employed as a mild and selective methylation reagent for the synthesis of various organic compounds. It is also used as a solvent in chemical reactions and as a stabilizer in certain formulations. 2-Methylpropylmethanesulphonate is considered to be relatively safe to handle and use, with low toxicity and minimal environmental impact.

InChI:InChI=1/C5H12O3S/c1-5(2)4-8-9(3,6)7/h5H,4H2,1-3H3

Upstream product

• 78-83-1 2-methyl-propan-1-ol 
• 124-63-0 methanesulfonyl chloride 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 32752-09-3 Diisobutyl-peroxid 
• 918900-74-0 benzyl 6-deoxy-6-(isobutylsulfonomethyl)-2,3,4-tri-O-benzyl-β-D-glucopyranoside 
• 1352399-57-5 isobytyl 4-(cyclohexa-1,4-dien-1-yl)butane-1-sulfonate 
• 161798-03-4 2-(3-formyl-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester 
• 359-00-2 1-fluoro-2-methylpropane 
• 115-11-7 isobutene 
• 2088-35-9 1,1-dichlorocyclopropane 
• 122836-35-5 sulfentrazone 
• 74792-80-6 2-hydroxy-2-methylpropyl methanesulfonate 
• 66868-67-5 4-(2-methylpropyl)sulfenyl-2-nitroaniline 
• 918900-76-2 benzyl 6-deoxy-6-[(isobutylsulfono)difluoromethyl]-2,3,4-tri-O-benzyl-β-D-glucopyranoside 
• 918900-75-1 benzyl 6-deoxy-6-[(isobutylsulfono)fluoromethyl]-2,3,4-tri-O-benzyl-β-D-glucopyranoside 

Relevant articles and documents

Electrochemical Deoxygenative Thiolation of Preactivated Alcohols and Ketones

This work describes an electrochemically promoted nickel-catalyzed deoxygenative thiolation of alcohols and ketones under mild conditions. Excellent substrate tolerance and good chemical yields can be achieved by graphene/nickel foam electrodes in an undivided cell. Further study to gain mechanistic insight into this electrochemical cross-coupling has been carried out.

Multi-Gram Scale Synthesis of 1,2,3-Triazolium Ionic Liquids and Assay of Their Resistance towards Bases

An easily upscalable synthesis method for 1,2,3-triazolium ionic liquids is presented. Several ionic liquids were synthesized and characterized. The influence of the side chain structure on the base-stability was investigated. One example, functionalized with linear alkyl side chains, was found to exhibit excellent stability against hot concentrated NaOH solutions and Grignard reagents.

HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS

A compound of formula (I): wherein either B is absent and A and Z are the same or different and are each hydrogen, halogen, alkyl, hydroxy, alkoxy,-CN,-C(Rc)2OH,-N(Rd)C(=X)Rc,-C(=X)N(Rc)(Rd),-S(O)m-Rc,-N(Rc)(Rd)S(O)2,-S(O)2N(R c)(Rd),-N(Re)2, aryl optionally substituted with Ra or-O-aryl optionally substituted with Ra; or B is present and is-(CH2)n-,-C(Rb)2-or-O-, or B taken together with A or Z can be-C=C(Rb)-,-C(Rb)=C-,-CH2-CH(R b)-or-CH(Rb)-CH2-; D is-O-or-S(O) m,-; E is a bond or is-(CH2)n-,-N(R d)-,-(CH2)nN(Rd)-or-N(R d)(CH2)n-; F is-C(=X)-; G is-(CH2 )n-,-N(Rd)-,-(CH2)nN(R d)-or-N(Rd)(CH2)n; J is a bond,-O-,-N(RC)C(=X)-,-C(=X)N(Rc)-,-S(O)m,-,-N(Rc)S(O)m-,-S(O)nN(Rc)-,-N(Re)-or-N(Rg)(Rh); K is a bond, alkylene, cycloalkylene, cycloalkenylene, arylene, heterocycloalkylene, heterocycloalkylene or heteroarylene; and L is hydrogen or a terminal group; has therapeutic utility.