1619-56-3

Usage

Uses

Used in Food and Beverage Industry:
Ethyl 2-cyano-2-ethylbutyrate is used as a flavoring agent for its pleasant, fruity, pineapple-like odor, enhancing the aroma and taste of various food and beverage products.
Used in Perfume Industry:
Ethyl 2-cyano-2-ethylbutyrate is used as a fragrance ingredient in the production of perfumes and other consumer products, contributing to their overall scent profile.
Used in Consumer Product Industry:
Ethyl 2-cyano-2-ethylbutyrate is used in the formulation of various consumer products, such as air fresheners and cleaning products, for its appealing fruity scent.

Upstream product

• 75-03-6 ethyl iodide 
• 105-56-6 ethyl 2-cyanoacetate 
• 7647-01-0 hydrogenchloride 
• 100383-87-7 2-ethyl-2-cyano-butyrimidic acid ethyl ester 
• 64-17-5 ethanol 
• 126245-49-6 (2-ethyl-2-cyano-butyryl)-urea 
• 7664-93-9 sulfuric acid 
• 74-96-4 ethyl bromide 
• 18852-51-2 sodium cyanoacetic acid ethyl ester 

Downstream Products

• 58042-95-8 acide 5,5-diethyl-4-iminobarbiturique 
• 617-80-1 2-ethyl-butyronitrile 
• 4386-07-6 2-ethyl-2-cyano-butyric acid 
• 90726-82-2 2-ethyl-2-aminomethyl-butyric acid ethyl ester 
• 119-61-9 benzophenone 
• 2983-38-2 ethyl 2-ethylbutanoate 
• 597-49-9 3-ethylpentan-3-ol 
• 96-22-0 pentan-3-one 
• 58042-95-8 5,5-diethyl-4-iminobarbiturate 
• 57-44-3 diethylbarbituric acid 
• 5682-46-2 2-Ethylbutyrophenon 
• 1426841-47-5 2,2-diethyl-4-phenylbut-3-yn-1-amine 
• 1426841-43-1 2,2-diethyl-4-phenylbut-3-ynenitrile 
• 82295-08-7 2-cyano-2-ethyl-N-phenylbutanamide 

Relevant academic research and scientific papers

Synthesis of variously 9,9-dialkylated octahydropyrimido [3,4-a]-s-triazines with potential antifungal activity

9,9-Dialkyloctahydropyrimido[3,4-a]-s-triazines were synthesized by iminodimethylation reaction between a 5,5-dialkyl-6-aminopyrimidine-2,4(3H,5H)-dione, a substituted aniline and two moles of formaldehyde. The synthesis of 5,5-dialkyl-6-aminopyrimidinedione consisted of the condensation of urea with ethyl 2,2-dialkylcyanoacetates. 18 Octahydropyrimido[3,4-a]-s-triazines were synthesized and compounds resulting from a supplementary aminomethylation were also obtained. Most of these compounds were tested for antifungal activity in vitro. Only 9,9-dibutyl-6,8-dioxo-3(2-chlorophenyl)2,3,4,5,6,7,8,9-octahydropyrimido[3, 4-a]-s-triazine showed some activity against Microsporum canis.

Au-catalyzed synthesis of 5,6-dihydro-8H-indolizin-7-ones from N-(pent-2-en-4-ynyl)-β-lactams

(Chemical Equation Presented) Au-catalyzed synthesis of 5,6-dihydro-8H-indolizin-7-ones from readily available N-(pent-2-en-4-ynyl)- β-lactams is developed. In this reaction, a 5-exo-dig cyclization of the β-lactam nitrogen to the Au-activated C-C triple bond is followed by heterolytic fragmentation of the amide bond, forming a highly nucleophilic acyl cation. An expedient formal synthesis of indolizidine 167B was easily achieved using this new method.

The design and synthesis of potent cyclic peptide VCAM-VLA-4 antagonists incorporating an achiral Asp-Pro mimetic

The Asp-Pro sequence of the cyclic peptide Ac-HN-Tyr-Cys*-Asp-Pro-Cys*-OH (1) could be replaced with the achiral dipeptide mimetic 1-(2-aminoethyl)cyclpentylcarboxylic acid with retention of potent inhibition of the VCAM-VLA-4 interaction. (C) Elsevier Science Ltd. All rights reserved.

Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region)

Analogs of the antitumor agents cryptophycins 1 and 8 with dialkyl substitution at C-6 (fragment C) were synthesized and evaluated for in vitro cytotoxicity against human leukemia cells (CCRF-CEM). The activity of these analogs decreased as the size of the substituents at C-6 increased. The C-6 spirocylopropyl compound (2g) was highly potent in vitro and showed excellent antitumor activity in animal models.