1619-56-3

Basic information

• Product Name: ethyl 2-cyano-2-ethylbutyrate
• Synonyms: Ethyl 2-cyano-2-ethylbutyrate; ethyl 2-cyano-2-ethylbutanoate
• CAS NO: 1619-56-3
• Molecular Formula: C₉H₁₅NO₂
• Molecular Weight: 169.2209
• EINECS: 216-580-5
• Mol File: 1619-56-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 214.5°C at 760 mmHg
• Flash Point: 90.2°C
• Density: 0.972g/cm³
• Vapor Pressure: 0.155mmHg at 25°C
• Refractive Index: 1.434
• CAS DataBase Reference: ethyl 2-cyano-2-ethylbutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-cyano-2-ethylbutyrate(1619-56-3)
• EPA Substance Registry System: ethyl 2-cyano-2-ethylbutyrate(1619-56-3)

Safety Data

• Hazardous Substances Data: 1619-56-3(Hazardous Substances Data)

Usage

General Description

Ethyl 2-cyano-2-ethylbutyrate is a chemical compound with the molecular formula C10H17NO2. It is a colorless liquid with a fruity, pineapple-like odor, commonly used as a flavoring agent in the food and beverage industry. It is also used in the production of perfumes and other consumer products. Ethyl 2-cyano-2-ethylbutyrate is known to be a mild irritant to the skin and eyes, and should be handled with caution. Its pleasant odor and flavor make it a popular choice in the creation of various products, contributing to their overall aroma and taste.

Upstream product

• 7647-01-0 hydrogenchloride 
• 100383-87-7 2-ethyl-2-cyano-butyrimidic acid ethyl ester 
• 64-17-5 ethanol 
• 126245-49-6 (2-ethyl-2-cyano-butyryl)-urea 
• 7664-93-9 sulfuric acid 
• 74-96-4 ethyl bromide 
• 75-03-6 ethyl iodide 
• 105-56-6 ethyl 2-cyanoacetate 
• 18852-51-2 sodium cyanoacetic acid ethyl ester 

Downstream Products

• 617-80-1 2-ethyl-butyronitrile 
• 4386-07-6 2-ethyl-2-cyano-butyric acid 
• 90726-82-2 2-ethyl-2-aminomethyl-butyric acid ethyl ester 
• 57-44-3 diethylbarbituric acid 
• 58042-95-8 5,5-diethyl-4-iminobarbiturate 
• 58042-95-8 acide 5,5-diethyl-4-iminobarbiturique 
• 119-61-9 benzophenone 
• 2983-38-2 ethyl 2-ethylbutanoate 
• 204514-21-6 2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-ethylbutanoic acid 
• 223763-94-8 (E)-(3S,10R,16S)-10-(3-Chloro-4-methoxy-benzyl)-6,6-diethyl-3-isobutyl-16-((E)-(R)-1-methyl-3-phenyl-allyl)-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone 
• 223763-99-3 (E)-(3S,10R,16S)-16-((1R,2R,3S)-3-Chloro-2-hydroxy-1-methyl-3-phenyl-propyl)-10-(3-chloro-4-methoxy-benzyl)-6,6-diethyl-3-isobutyl-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone 
• 5682-46-2 2-Ethylbutyrophenon 
• 1426841-47-5 2,2-diethyl-4-phenylbut-3-yn-1-amine 
• 1426841-43-1 2,2-diethyl-4-phenylbut-3-ynenitrile 

Relevant articles and documents

Synthesis of variously 9,9-dialkylated octahydropyrimido [3,4-a]-s-triazines with potential antifungal activity

9,9-Dialkyloctahydropyrimido[3,4-a]-s-triazines were synthesized by iminodimethylation reaction between a 5,5-dialkyl-6-aminopyrimidine-2,4(3H,5H)-dione, a substituted aniline and two moles of formaldehyde. The synthesis of 5,5-dialkyl-6-aminopyrimidinedione consisted of the condensation of urea with ethyl 2,2-dialkylcyanoacetates. 18 Octahydropyrimido[3,4-a]-s-triazines were synthesized and compounds resulting from a supplementary aminomethylation were also obtained. Most of these compounds were tested for antifungal activity in vitro. Only 9,9-dibutyl-6,8-dioxo-3(2-chlorophenyl)2,3,4,5,6,7,8,9-octahydropyrimido[3, 4-a]-s-triazine showed some activity against Microsporum canis.

The design and synthesis of potent cyclic peptide VCAM-VLA-4 antagonists incorporating an achiral Asp-Pro mimetic

The Asp-Pro sequence of the cyclic peptide Ac-HN-Tyr-Cys*-Asp-Pro-Cys*-OH (1) could be replaced with the achiral dipeptide mimetic 1-(2-aminoethyl)cyclpentylcarboxylic acid with retention of potent inhibition of the VCAM-VLA-4 interaction. (C) Elsevier Science Ltd. All rights reserved.