1629-25-0

Upstream product

• 366-75-6 N-(4-fluorophenyl)benzamide 
• 371-40-4 4-fluoroaniline 
• 65-85-0 benzoic acid 
• 100-52-7 benzaldehyde 
• 98-88-4 benzoyl chloride 
• 6313-36-6 benzyl thiosulphate 

Downstream Products

• 1629-94-3 6-fluoro-2-(p-tolyl)benzo[d]thiazole 

Relevant academic research and scientific papers

Unveiling photodeactivation pathways for a new iridium(III) cyclometalated complex

We report the synthesis and characterization of a neutral heteroleptic IrIII complex bearing 6-fluoro-2-phenylbenzo[d]thiazole as cyclometalating ligand and (Z)-6-(9H-carbazol-9-yl)-5-hydroxy-2,2-dimethylhex-4- en-3-one as ancillary ligand. The

Visible-Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions

A metal-free heterogeneous photocatalysis has been developed for the synthesis of benzothiazoles via intramolecular C-H functionalization/C-S bond formation of thiobenzanilides by inexpensive graphitic carbon nitride (g-C3N4) under visible-light irradiation. This reaction provides access to a broad range of 2-substituted benzothiazoles in high yields under an air atmosphere at room temperature without addition of a strong base or organic oxidizing reagents. In addition, the catalyst was found to be stable and reusable after five reaction cycles.

Exogenous Photosensitizer-, Metal-, and Base-Free Visible-Light-Promoted C-H Thiolation via Reverse Hydrogen Atom Transfer

Visible-light-driven, intramolecular C(sp2)-H thiolation has been achieved without addition of a photosensitizer, metal catalyst, or base. This reaction induces the cyclization of thiobenzanilides to benzothiazoles. The substrate absorbs visible light, and its excited state undergoes a reverse hydrogen-atom transfer (RHAT) with 2,2,6,6-tetramethylpiperidine N-oxyl to form a sulfur radical. The addition of the sulfur radical to the benzene ring gives an aryl radical, which then rearomatizes to benzothiazole via RHAT.

Transition metal-free α-Csp3-H oxidative sulfuration of benzyl thiosulfates with anilines to form N-aryl thioamides

A metal-free approach to N-aryl thioamides from Bunte salts and anilines in DMSO has been developed. This method tolerated a wide range of functional groups on the aromatic ring, providing an ideal way to N-aryl thioamides in good to excellent yields from cheap and easily available starting materials. A plausible mechanism was also proposed based on the X-ray single crystal diffraction, NMR and MS analyses of DMSO-concerning intermediates.

Organocatalytic syntheses of benzoxazoles and benzothiazoles using aryl iodide and oxone via C-H functionalization and C-O/S bond formation

An organocatalytic protocol for the syntheses of 2-substituted benzoxazoles and benzothiazoles is described from alkyl-/arylanilides and alkyl-/arylthioanilides using 1-iodo-4-nitrobenzene as catalyst and oxone as an inexpensive and environmentally safe terminal oxidant at room temperature in air via oxidative C-H functionalization and C-O/S bond formation. The procedure is simple and general and provides an effective route for the construction of functionalized 2-alkyl-/arylbenzoxazoles and 2-alkyl-/arylbenzothiazoles with moderate to high yields. The synthetic and mechanistic aspects have been described.

Synthesis of thioamides by catalyst-free three-component reactions in water

Three-component reactions involving amines, aldehydes, and elemental sulfur powder are reported to afford thioamides in a simple one-pot procedure in the absence of a catalyst. A variety of thioamides can be obtained in good to excellent yields up to 88 %. Three-component reactions involving amines, aldehydes, and sulfur powder afford thioamides in a simple one-pot procedure. A variety of substituted thioamides are obtained in good to excellent yields up to 88 %. Copyright

Homoleptic tris-cyclometalated iridium complexes with 2-phenylbenzothiazole ligands for highly efficient orange OLEDs

Homoleptic tris-cyclometalated iridium(iii) complexes containing 2-phenylbenzothiazole derivatives as ligands have been successfully synthesized and characterized for the first time. Electron-donating (CH3, OCH3) and -withdrawing groups (F) were introduced into the 6-position of the benzothiazole moiety in the ligands to verify their influence on the optical and electronic properties of the complexes. Organic light-emitting diodes using these iridium complexes as doped emitters exhibited orange electrophosphorescence with excellent performances. An extremely high brightness of 95800 cd m-2 and a maximum luminance efficiency of 87.9 cd A -1 (46.0 lm W-1) were achieved for the pristine complex without any substituent in the ligand. These performances represent a significant improvement for vacuum-deposited orange OLEDs and the new record of the efficiencies for orange OLEDs reported so far. The substituents in the ligand were observed to be rather unimportant to influence the performance of this series of iridium complexes.

Antimycobacterial activity of 3'- and 4'-fluorothiobenzanilides

On the basis of a preliminary study of the antimycobacterial activity of thiobenzanilides, a group of 3/-fluoro- and 4/fluorothiobenzanilides has been synthesized and tested against Mycobacterium tuberculosis, M. kansasii, M. avium and M. fortuitum. The r