163656-30-2Relevant articles and documents
An efficient synthesis of 2,4-difluoro-3,5-dichlorobenzoic acid
Zhou, Weiyou,Yu, Shuitao,Xia, Zhengjun,Zhang, Mingguang,Lin, Song,Chen, Zaixin
, p. 277 - 278 (2015)
2,4-Difluoro-3,5-dichlorobenzoic acid, as a key intermediate for preparing quinolone-3-carboxylic acids, was synthesised from the commercially available 2,4-difluoro-3-chlorobenzoic acid in excellent yield by a reaction sequence involving nitration, selec
2,3,4,5-tetrahalogenobenzene derivatives
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, (2008/06/13)
2,3,4,5-trihalogenobenzene derivatives of the formula STR1 in which R is --COOH, --COCl, --COF, --CN, --CONH2, --CH2 OH, --CH2 Cl, --CHCl2, --CCl3 or --CHO, R1 is H, Cl or F, and R2 is Cl or F, it only being possible for R1 or R2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone carboxylic acids.