163656-30-2Relevant academic research and scientific papers
An efficient synthesis of 2,4-difluoro-3,5-dichlorobenzoic acid
Zhou, Weiyou,Yu, Shuitao,Xia, Zhengjun,Zhang, Mingguang,Lin, Song,Chen, Zaixin
, p. 277 - 278 (2015)
2,4-Difluoro-3,5-dichlorobenzoic acid, as a key intermediate for preparing quinolone-3-carboxylic acids, was synthesised from the commercially available 2,4-difluoro-3-chlorobenzoic acid in excellent yield by a reaction sequence involving nitration, selec
Lithiations directed by carboxylic acid, fluorine and chlorine: The regioselective synthesis of polysubstituted benzoic acids and acetophenones
Moyroud, Joel,Guesnet, Jean-Luc,Bennetau, Bernard,Mortier, Jacques
, p. 133 - 141 (2007/10/03)
Lithiation/electrophilic quenching of ortho-lithiated benzoates allows the totally regiocontrolled synthesis of a wide range of 2,3-, 2,3,4-, and 2,3,4,5-polysubstituted benzoic acids and related acetophenones. Elsevier,.
2,3,4,5-tetrahalogenobenzene derivatives
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, (2008/06/13)
2,3,4,5-trihalogenobenzene derivatives of the formula STR1 in which R is --COOH, --COCl, --COF, --CN, --CONH2, --CH2 OH, --CH2 Cl, --CHCl2, --CCl3 or --CHO, R1 is H, Cl or F, and R2 is Cl or F, it only being possible for R1 or R2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone carboxylic acids.
Fluorobenzoates and process for their production
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, (2008/06/13)
A fluorobenzoate having the formula: STR1 wherein X is a fluorine atom or a hydrogen atom, and R is an alkyl group.
