16492-75-4

Usage

Uses

Used in Pharmaceutical Synthesis:
1,2,3-Benzenetriol, 5-bromois used as an intermediate in the synthesis of pharmaceuticals for its unique properties and reactivity. The presence of the bromine group allows for further functionalization and modification of the molecule, making it a versatile building block in the development of new drugs.
Used in Dye Synthesis:
1,2,3-Benzenetriol, 5-bromois used as a precursor in the synthesis of dyes due to its ability to form colored compounds. The bromine atoms in the molecule can be replaced with other functional groups, leading to the formation of various dyes with different colors and properties.
Used in Organic Compounds Synthesis:
1,2,3-Benzenetriol, 5-bromois used as a starting material in the synthesis of other organic compounds. Its reactivity and the presence of the bromine group make it suitable for various organic reactions, such as substitution, addition, and coupling reactions, to produce a wide range of organic compounds.
Used in Antioxidant Applications:
1,2,3-Benzenetriol, 5-bromois used as an antioxidant due to its ability to scavenge free radicals and protect cells from oxidative damage. Its antioxidant properties have been studied for potential use in the treatment of diseases associated with oxidative stress, such as cancer and diabetes.
Used in Cancer Treatment Research:
1,2,3-Benzenetriol, 5-bromohas been studied for its potential use in the treatment of cancer due to its ability to modulate various signaling pathways involved in tumor growth and progression. Further research is needed to explore its efficacy and safety as a cancer therapeutic agent.

Upstream product

• 133932-61-3 5-bromo-2-methoxybenzene-1,3-diol 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 70654-71-6 4-bromo-2,6-dimethoxyphenol 
• 2675-79-8 1-bromo-3,4,5-trimethoxybenzene 
• 17345-74-3 4,5,6-tribromo-pyrogallol 

Downstream Products

• 695816-76-3 5-bromo-1,2,3-tris(decyloxy)benzene 
• 695816-77-4 3,4,5-tri((3S)-3,7-dimethyl-1-octyloxy)bromobenzene 
• 875753-80-3 C₃₃H₅₉BrO₁₅ 
• 1041859-46-4 5-bromo-1,2,3-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene 
• 1092504-79-4 C₉₀H₇₇BrO₁₂ 
• 1135950-13-8 (R,R,R)-5-bromo-1,2,3-tris-(2-[2-(2-(2-[2-(2-methoxyethoxy)ethoxy]ethoxy)ethoxy)ethoxy]ethoxy-2-propoxy)benzene 
• 1135950-12-7 5-bromo-1,2,3-tris-(2-[2-(2-(2-[2-(2-methoxyethoxy)ethoxy]ethoxy)ethoxy)ethoxy]ethoxy)benzene 
• 1239569-10-8 5-bromo-1,2,3-triicosyloxybenzene 
• 1329426-07-4 1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4,5-tridodecyloxybenzene 
• 1329426-08-5 4,4,5,5-tetramethyl-2-(3,4,5-tris-(n-octyloxy)phenyl)-1,3,2-dioxaborolane 
• 1329426-10-9 2-bromo-5-(3,4,5-tris(dodecyloxy)phenyl)thiophene 
• 1431387-94-8 13,13′,13″-[(5-bromobenzene-1,2,3-triyl)tris(oxy)]tris-(2,5,8,11,15,18,21,24-octaoxapentacosane) 
• 1186495-57-7 5-ethynyl-1,2,3-tri(hexyloxy)benzene 

Relevant academic research and scientific papers

Membrane-Anchoring Photosensitizer with Aggregation-Induced Emission Characteristics for Combating Multidrug-Resistant Bacteria

Traditional photosensitizers (PSs) show reduced singlet oxygen (1O2) production and quenched fluorescence upon aggregation in aqueous media, which greatly affect their efficiency in photodynamic therapy (PDT). Meanwhile, non-targetin

Synthesis and helical supramolecular organization of discotic liquid crystalline dibenzo[: Hi, st] ovalene

Dibenzo[hi,st]ovalene (DBOV) has emerged as a new polycyclic aromatic hydrocarbon (PAH) with intriguing optical properties with strong red emission. Nevertheless, DBOV derivatives thus far synthesized either had mesityl groups that hinder the π-π stacking

Synthesis and Liquid Crystalline Self-Assembly of Concave Diindoles with a Hydropentalene Core

Fischer indole reaction of Weiss diketone with 4-bromophenylhydrazine provided the 2,8-dibromo-hexahydropentaleno[2,1-b:5,4-b’]diindole key intermediate, which was converted to the target compounds by N-protection/Suzuki cross-coupling. Variation of prote

Thermotropic columnar liquid crystals based on wedge-shaped phenylphosphonic acids

Wedge-shaped phenylphosphonic acids with variation in the peripheral alkoxy chains have been synthesized. These derivatives show a hexagonal columnar liquid-crystalline behavior upon thermal treatment. These materials have potential to be used as efficien

A Membrane-Intercalating Conjugated Oligoelectrolyte with High-Efficiency Photodynamic Antimicrobial Activity

A membrane-intercalating conjugated oligoelectrolyte (COE), PTTP, was designed and synthesized with the goal of providing red-shifted absorption spectra relative to previously synthesized COE analogs. Specifically, electron-rich and electron-poor subunits were introduced in the conjugated backbone to modulate the band gap. PTTP exhibits maxima of absorption at 507 nm and of emission at 725 nm. PTTP can also efficiently function to generate singlet oxygen in situ (ΦΔ≈20 %) and has appropriate topology and dimensions to interact with lipid membranes. The resulting rapid membrane insertion and sensitizing ability provide PTTP with a highly efficient antibacterial capability under a low light dose (0.6 J cm?2) toward Gram-negative bacteria E. coli, making it a remarkably efficient optically mediated antimicrobial agent.

Tetradentate platinum(II) complexes: Synthesis, photophysical properties, liquid crystalline characteristics and charge transport behaviour

Three new tetradentate phosphorescent Pt(II) complexes (Pt6, Pt12 and Pt16) with half-disc molecule structure were designed and synthesized, which are based on tetradentate ligands with six alkoxyl chains on the periphery,

A columnar liquid crystal with permanent polar order

The self-assembly of axial dipolar subphthalocyanine molecules in the presence of electric fields leads to uniaxially oriented columnar liquid crystalline materials that exhibit permanent polarization.

Partially stripped insulated nanowires: A lightly substituted hexa-peri-hexabenzocoronene-based columnar liquid crystal

We present the facile preparation and characterization of the first "unwrapped" hexa-peri-hexabenzocoronene derivative, which forms a stable columnar liquid crystalline mesophase with a practically accessible isotropization temperature.

Efficient preparation of stereopure amphiphilic 1,2-amino alcohols by using preparative enantioselective HPLC

Chiral amphiphiles are useful for controlling the structures and properties of supramolecular assemblies, but their stereocontrolled synthesis is generally difficult, because their long alkyl chains tend to bring unfavorable effects on the solubility, rea

Tuning the Molecular Packing of Self-Assembled Amphiphilic PtII Complexes by Varying the Hydrophilic Side-Chain Length

Understanding the relationship between molecular design and packing modes constitutes one of the major challenges in self-assembly and is essential for the preparation of functional materials. Herein, we have achieved high precision control over the supramolecular packing of amphiphilic PtII complexes by systematic variation of the hydrophilic side-chain length. A novel approach of general applicability based on complementary X-ray diffraction and solid-state NMR spectroscopy has allowed us to establish a clear correlation between molecular features and supramolecular ordering. Systematically increasing the side-chain length gradually increases the steric demand and reduces the extent of aromatic interactions, thereby inducing a gradual shift in the molecular packing from parallel to a long-slipped organization. Notably, our findings highlight the necessity of advanced solid-state NMR techniques to gain structural information for supramolecular systems where single-crystal growth is not possible. Our work further demonstrates a new molecular design strategy to modulate aromatic interaction strengths and packing arrangements that could be useful for the engineering of functional materials based on PtII and aromatic molecules.