165184-83-8Relevant articles and documents
Palladium catalyzed coupling reactions of β-perfluoroalkyl-substituted alkyl halides with organostannanes
Shimizu, Rie,Fuchikami, Takamasa
, p. 8405 - 8408 (1996)
β-Perfluoroalkyl-substituted alkyl halides reacted with organostannanes such as allyl-, phenylethynyl-, β-phenylethenyl-, and phenyl-tributyltin in the presence of palladium-phosphine complexes to give the corresponding cross-coupling products in good yie
Nickel-Catalyzed Coupling of Arylzinc Halides with Thioesters
Gehrtz, Paul H.,Kathe, Prasad,Fleischer, Ivana
supporting information, p. 8774 - 8778 (2018/06/26)
The Pd-catalyzed Fukuyama reaction of thioesters with organozinc reagents is a mild, functional-group-tolerant method for acylation chemistry. Its Ni-catalyzed variant might be a sustainable alternative to expensive catalytic Pd sources. We investigated the reaction of S-ethyl thioesters with aryl zinc halides with hetero- and homotopic Ni precatalysts and several ligands. The results show that both homo- and heterotopic species may contribute to catalysis. The substrate scope using an operationally homogeneous defined Ni complex was established. Acyl radicals are postulated as short-lived intermediates.
Enantiomeric resolution of fluorous mixture by chiral CD columns: Asymmetric reduction of a mixture of fluorous ketones
Nakamura, Yutaka,Takeuchi, Seiji,Okumura, Kazuo,Ohgo, Yoshiaki,Matsuzawa, Hiroshi,Mikami, Koichi
, p. 6221 - 6225 (2007/10/03)
Asymmetric reduction of a mixture of four fluorous ketone analogues was carried out with (R)-oxazaborolidine as a catalyst. The fluorous mixture products were resolved by a reverse phase HPLC with chiral β-cyclodextrin column to result in good separation of the enantiomers.
