165550-81-2

Basic information

• Product Name: N-(4-phenoxyphenyl)formamide
• Synonyms: formamide, N-(4-phenoxyphenyl)-; N-(4-Phenoxyphenyl)formamide
• CAS NO: 165550-81-2
• Molecular Formula: C₁₃H₁₁NO₂
• Molecular Weight: 213.2319
• Mol File: 165550-81-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 391.6°C at 760 mmHg
• Flash Point: 190.6°C
• Density: 1.206g/cm³
• Vapor Pressure: 2.44E-06mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: N-(4-phenoxyphenyl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-phenoxyphenyl)formamide(165550-81-2)
• EPA Substance Registry System: N-(4-phenoxyphenyl)formamide(165550-81-2)

Safety Data

• Hazardous Substances Data: 165550-81-2(Hazardous Substances Data)

Upstream product

• 59377-19-4 p-phenoxyphenylisocyanate 
• 21382-99-0 4-dimethylaminodiphenyl ether 
• 68-12-2 N,N-dimethyl-formamide 
• 139-59-3 4-phenoxyanilin 
• 620-88-2 4-nitrophenyl phenyl ether 
• 350-46-9 4-Fluoronitrobenzene 
• 108-95-2 phenol 
• 64-18-6 formic acid 
• 124-38-9 carbon dioxide 

Relevant articles and documents

Copper-Catalyzed Cascade N-Dealkylation/N-Methyl Oxidation of Aromatic Amines by Using TEMPO and Oxygen as Oxidants

A novel tandem N-dealkylation and N-methyl aerobic oxidation of tertiary aromatic amines to N-arylformamides using copper and TEMPO has been developed. This methodology suggested an alternative synthetic route from N-methylarylamines to N-arylformamides.

A Practical Approach for the Transamidation of N, N-Dimethyl Amides with Primary Amines Promoted by Sodium tert-Butoxide under Solvent-Free Conditions

A practical sodium tert-butoxide (NaO t Bu)-mediated protocol is disclosed for the transamidation of various N, N-dimethyl amides with primary amines to afford the corresponding amides in moderate to good yields at room temperature under solvent-free conditions. This protocol features a facile work-up procedure and good functional group compatibility, especially for N, N-dimethyl amides with long-chain alkyl groups and heteroatom-containing amines. Notably, a few representative gram-scale reactions proceed smoothly to furnish the desired amides in high yields, which demonstrates the potential of this process for further practical applications. Several control experiments are carried out and a plausible mechanism is provided.

Efficient: N -formylation of primary aromatic amines using novel solid acid magnetic nanocatalyst

Sulfonic acid functionalized over biguanidine fabricated silica-coated heterogeneous magnetic nanoparticles (NP?SO3H) have been synthesized, well characterized and explored for the first time, as an efficient and recyclable catalyst for N-formylation of primary amines under mild reaction conditions. Exploiting the magnetic nature of Fe3O4, the prepared catalyst was readily recovered from the reaction mixture via an external magnet. The catalyst can be reused for up to six cycles without any substantial loss of catalytic activity. The cost effectiveness, simple methodology, wide substrate tolerance, excellent yield and easy work-up are the additional advantages of present catalytic system. This journal is