1660-24-8

Basic information

• Product Name: Benzoic acid, 2-methylhydrazide (6CI,7CI,8CI,9CI)
• Synonyms: Benzoic acid, 2-methylhydrazide (6CI,7CI,8CI,9CI);N-Methylbenzeneformhydrazonic acid;N'-Methylbenzhydrazide
• CAS NO: 1660-24-8
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Product Categories: AMIDE
• Mol File: 1660-24-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 86-88 °C
• Boiling Point: 214.1±13.0 °C(Predicted)
• Appearance: /
• Density: 1.083±0.06 g/cm3(Predicted)
• PKA: 12?+-.0.23(Predicted)
• CAS DataBase Reference: Benzoic acid, 2-methylhydrazide (6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-methylhydrazide (6CI,7CI,8CI,9CI)(1660-24-8)
• EPA Substance Registry System: Benzoic acid, 2-methylhydrazide (6CI,7CI,8CI,9CI)(1660-24-8)

Safety Data

• Hazardous Substances Data: 1660-24-8(Hazardous Substances Data)

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 60-34-4 methylhydrazine 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 613-94-5 benzoic acid hydrazide 
• 77-78-1 dimethyl sulfate 
• 6327-62-4 N'-acetyl-N'-methylbenzohydrazide 

Downstream Products

• 51592-30-4 N'-Benzoyl-N-methyl-hydrazinecarbodithioic acid methyl ester 
• 1006-19-5 1-methyl-1,2-dihydro-3H-indazol-3-one 
• 59190-07-7 3-(2-methyl-5-phenyl-2H-[1,2,4]triazol-3-yl)-pyridine 
• 21150-15-2 N,N'-dibenzoyl-N-methyl-hydrazine 
• 104637-71-0 2-(α-Chlorphenylmethylen)-N,1-dimethyl-hydrazinsulfonamid 
• 104637-74-3 2,5-Dimethyl-4-phenyl-2,5-dihydro-1,2,3,5-thiatriazol-1,1-dioxid 
• 879-60-7 3-methyl-5-phenyl-1,3,4-oxadiazol-2(3H)-one 
• 774-65-2 benzoic acid tert-butyl ester 
• 77919-29-0 1-Benzoyl-2-methyl-4-phenylsemicarbazid 
• 80791-37-3 nonyl 3-benzoyl-2-methyldithiocarbazate 
• 13281-47-5 1,4-Dibenzoyl-2-methylthiosemicarbazid 
• 51592-28-0 N'-Benzoyl-N-methyl-hydrazinecarbothioic acid O-methyl ester 
• 57676-40-1 3-methyl-5-phenyl-2,3-dihydro-[1,3,4]oxadiazole 

Relevant articles and documents

Ruthenium-Catalyzed Three-Component Alkylation: A Tandem Approach to the Synthesis of Nonsymmetric N,N-Dialkyl Acyl Hydrazides with Alcohols

The borrowing hydrogen strategy has been applied in the synthesis of nonsymmetric N,N-dialkylated acyl hydrazides via a tandem three-component reaction catalyzed by a phosphine free diaminocyclopentadienone ruthenium tricarbonyl complex. This strategy represents the first direct one-pot approach to nonsymmetric functionalized acyl hydrazides. Different aromatic acyl hydrazides underwent dialkylation with a variety of primary or secondary alcohols and methanol or ethanol as alkylating agents in mild reaction conditions and good yields. Deuterium labelling experiments suggested that the primary or secondary alcohol was the hydrogen source in this tandem process. DFT calculations show that the combination of the tandem mixed product cannot be perfectly explained neither structurally nor electronically, but might be dependent of the physical state of the aldehyde or ketone intermediate (gaz vs. liquid) at the reaction temperature. (Figure presented.).

Conformational control ofN-methyl-N,N'-diacylhydrazines by noncovalent carbon bonding in solution

In recent years, some X-ray structural and computational evidence has emerged for noncovalent carbon bonding (C-bond). However, evidence of C-bonds in solution is limited. Herein, from the conformational analyses of strategically designedN-methyl-N,N'-dia

Synthesis of 3-methyl-[1,2,4]-triazepino[6,5,4-jk]carbazol-4(3H)one

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