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Usage

Uses

Used in Food Industry:
1-(2-HYDROXY-5-METHYLPHENYL)BUTANE-1,3-DIONE is used as a coloring agent for its vibrant yellow hue, adding visual appeal to various food products. It is also utilized as a flavoring agent, imparting a unique taste to the dishes it is added to.
Used in Pharmaceutical Applications:
Curcumin is being researched for its potential therapeutic applications in various diseases and conditions, such as cancer, arthritis, and Alzheimer's disease. Its anti-inflammatory and antioxidant properties make it a promising candidate for the development of new treatments and medications.
Used in Dietary Supplements:
1-(2-HYDROXY-5-METHYLPHENYL)BUTANE-1,3-DIONE is considered safe for consumption and is available as a dietary supplement for individuals seeking to benefit from its potential health advantages. These supplements may help support overall well-being and promote a healthy lifestyle.

Upstream product

• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 140-39-6 1-acetoxy-4-methylbenzene 
• 141-78-6 ethyl acetate 
• 107089-91-8 2,6-dimethyl-4-oxo-4H-chromene-3-carboxylic acid 

Downstream Products

• 20933-30-6 3-ethylamino-1-(2-hydroxy-5-methyl-phenyl)-but-2-en-1-one 
• 16108-51-3 2,6-dimethyl-chromen-4-one 
• 859085-54-4 2,6-dimethyl-3-propionyl-chromen-4-one 
• 93598-99-3 2-[1-Dimethylamino-meth-(E)-ylidene]-1-(2-hydroxy-5-methyl-phenyl)-butane-1,3-dione 
• 93598-97-1 2-(2-hydroxy-5-methylbenzoyl)-7-methyl-9H-xanthen-9-one 
• 104516-48-5 1-hydroxy-3-(2-hydroxy-5-methylphenyl)-5-methylpyrazole 
• 20933-37-3 3-(2-hydroxy-5-methylphenyl)-5-methylpyrazole 
• 4105-92-4 triethyl benzene-1,3,5-tricarboxylate 
• 56686-34-1 1-(2-hydroxy-3,5-dimethylphenyl)butane-1,3-dione dioxime 
• 20933-38-4 4-methyl-2-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-phenol 

Relevant academic research and scientific papers

One-pot synthesis of 3-(furan-2-yl)-4: H -chromen-4-ones from 1-(2-hydroxyphenyl)butane-1,3-diones and 2,5-dimethoxy-2,5-dihydrofuran catalyzed via K10 montmorillonite under solvent-free conditions

A new, concise and efficient method of one-pot synthesis of 3-(furan-2-yl)-4H-chromen-4-ones was developed using K10 montmorillonite catalysis under solvent-free conditions. The procedure of the synthesis of 3-(furan-2-yl)-4H-chromen-4-ones was that 1-(2-hydroxyphenyl)butane-1,3-diones and 2,5-dimethoxy-2,5-dihydrofuran underwent a process of α-alkoxyalkylation in the presence of K10 montmorillonite at 80 °C for 0.5 h and continuously at 120 °C for another 0.5 h. The advantages of this method were that it was solvent-free, the K10 montmorillonite was recyclable and it had an easy work-up.

Ruthenium-NHC-catalyzed asymmetric hydrogenation of flavones and chromones: General access to enantiomerically enriched flavanones, flavanols, chromanones, and chromanols

Two to four! Readily available flavones and chromones were efficiently converted into four valuable chiral classes of O-heterocycles - flavanones, chromanones, flavanols, and chromanols - by means of an enantioselective Ru/NHC-catalyzed hydrogenation process (see scheme; NHC=N-heterocyclic carbene, PCC=pyridinium chlorochromate). Copyright

Benzopyrans. Part 41.1 Reactions of 2-(2-dimethylaminovinyl)-lbenzopyran-4-ones with various dienophiles

Dienamine 1 with W-phenylmaleimide and chromenone 14 as well as 15 produces, through initial [4 + 2]cycloaddition, xanthenones 10 and 18, respectively. Initial Michael addition of 1 to chromenones 14 and 16, and dimethyl acetylenedicarboxylate (DMAD), triggers the formation of xanthenone 19, 4-azaxanthenone 26 and substituted fumarate 49, respectively. Initial [2 + 2]cycloadducts of dienamines 1-3 with electrophilic acetylenes always undergo further transformations. Thus, 1 with DMAD, dibenzoylacetylene and ethyl propiolate (EP) ultimately gives xanthenones 33, 34 and 37, respectively, the latter being admixed with flavone 43. Enamine 2, cyclisable to xanthenone 11, gives 33 and 35 with DMAD, and 37 and 44 with EP. Reaction of 3 with DMAD affords 36 exclusively. The Royal Society of Chemistry 1999.

Benzopyrans : Part 40 - Alumina mediated transformations of 4-oxo-4H-1- benzopyran-3-carbaldehyde, -3-carboxylic acid and their 2-methylhomologues

In contact with alumina, the title aldehyde 1 (R = H, Me, Cl) gives the chromones 5 and 9,12 whereas the acid 2 affords the chromones 7, 10 and acetophenone 23. Alumina converts the aldehyde 3 to the xanthone 14, and the corresponding acid 4 to the chromone 8 and diketone 24.