4105-92-4

Basic information

• Product Name: Triethyl 1,3,5-benzenetricarboxylate
• Synonyms: 1,3,5-Benzenetricarboxylic acid, triethyl ester;Triethyl trimesate;BENZENE-1,3,5-TRICARBOXYLIC ACID TRIETHYL ESTER;1,3,5-TRICARBOETHOXYBENZENE;TMSSE;TRIMESIC ACID TRIETHYL ESTER;TRIETHYL BENZENE-1,3,5-TRICARBOXYLATE;TRIETHYL 1,3,5-BENZENETRICARBOXYLATE
• CAS NO: 4105-92-4
• Molecular Formula: C₁₅H₁₈O₆
• Molecular Weight: 294.3
• Product Categories: C12 to C63;Carbonyl Compounds;Esters
• Mol File: 4105-92-4.mol
• Article Data: 61

Chemical Properties

• Melting Point: 134-139 °C(lit.)
• Boiling Point: 385.9°C at 760 mmHg
• Flash Point: 168.4°C
• Appearance: /
• Density: 1.164g/cm³
• Vapor Pressure: 3.68E-06mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Triethyl 1,3,5-benzenetricarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Triethyl 1,3,5-benzenetricarboxylate(4105-92-4)
• EPA Substance Registry System: Triethyl 1,3,5-benzenetricarboxylate(4105-92-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4105-92-4(Hazardous Substances Data)

Usage

Description

Triethyl 1,3,5-benzenetricarboxylate is a colorless liquid chemical compound with the formula C16H20O6, characterized by a fruity odor. It is widely recognized for its use as a fragrance ingredient in consumer products, as well as its applications in the plastics, pharmaceutical, and film industries.

Uses

Used in Fragrance Industry:
Triethyl 1,3,5-benzenetricarboxylate is used as a fragrance ingredient for its fruity scent, enhancing the aroma profiles in perfumes, colognes, and cosmetics.
Used in Plastics Industry:
In the plastics industry, Triethyl 1,3,5-benzenetricarboxylate is utilized as a plasticizer, contributing to the flexibility and workability of cellulose acetate films, which are essential in various applications such as photographic and packaging films.
Used in Pharmaceutical Industry:
Triethyl 1,3,5-benzenetricarboxylate serves as an intermediate in the synthesis of various drugs and pharmaceutical compounds, playing a crucial role in the development of new medications.
Used in Resin and Polymer Production:
Triethyl 1,3,5-benzenetricarboxylate is also employed in the manufacture of resins and polymers, where it contributes to the formation of materials with specific properties required for diverse applications.
Considering its low toxicity and general safety when handled and stored properly, Triethyl 1,3,5-benzenetricarboxylate is a versatile compound with significant applications across multiple industries.

InChI:InChI=1/C15H18O6/c1-4-19-13(16)10-7-11(14(17)20-5-2)9-12(8-10)15(18)21-6-3/h7-9H,4-6H2,1-3H3

Upstream product

• 141-78-6 ethyl acetate 
• 109-94-4 formic acid ethyl ester 
• 105-39-5 chloroacetic acid ethyl ester 
• 104-88-1 4-chlorobenzaldehyde 
• 119930-16-4 (E)-4-(Triphenyl-λ⁵-phosphanylidene)-pent-2-enedioic acid diethyl ester 
• 623-47-2 propynoic acid ethyl ester 
• 58-61-7 adenosine 
• 34780-29-5 3-oxo-propionic acid ethyl ester 
• 7664-41-7 ammonia 
• 64-17-5 ethanol 
• 5941-55-9 ethyl 3-ethoxyacrylate 
• 75-36-5 acetyl chloride 
• 1117-37-9 ethyl (E)-3-(dimethylamino)acrylate 
• 10601-80-6 ethyl 3,3-diethoxypropanoate 

Downstream Products

• 156750-11-7 5-(bromomethyl)isophthalic acid diethyl ester 
• 181426-03-9 C₇₃H₇₆O₂₃ 
• 181425-95-6 C₃₃H₃₆O₁₁ 
• 181425-99-0 C₃₃H₃₅BrO₁₀ 
• 38460-57-0 1,3,5-tris(mercaptomethyl)benzene 
• 86375-10-2 N¹,N³,N⁵- tribenzylbenzene-1,3,5-tricarboxamide 

Relevant articles and documents

REACTION OF NUCLEOBASES WITH α-ACETYLENIC ESTERS, POTENTIALLY USEFULL FOR CHEMICAL MODIFICATION OF NUCLEIC ACIDS

The NH2 group and the adjacent ring nitrogen of adenosine and cytidine react with α-acetylenic esters by addition across the triple bond and formation of a lactam with the ester group.

Understanding the Incorporation and Release of Salicylic Acid in Metal-Organic Frameworks for Topical Administration

Although metal-organic frameworks (MOFs) have been widely demonstrated to be great candidates for drug delivery applications, they have been mainly proposed for the intravenous route. Here, eight highly porous benchmarked MOFs, with different topologies a

Cyclotrimerization of alkynes catalyzed by a self-supported cyclic tri-nuclear nickel(0) complex with α-diimine ligands

A cyclic tri-nuclear α-diimine nickel(0) complex [{Ni(μ-LMe-2,4)}3] (2) was synthesized from a “pre-organized”, trimerized trigonal LNiBr2-type precursor [Ni3(μ2-Br)3(μ3-Br)2(LMe-2,4)3]·Br (1; LMe-2,4 = [(2,4-Me2C6H3)NC(Me)]2). In complex 2, the α-diimine ligands not only exhibit the normal N,N′-chelating mode, but they also act as bridges between the Ni atoms through an unusual π-coordination of a C═N bond to Ni. Complex 2 is able to catalyze the cyclotrimerization of alkynes to form substituted benzenes in good yield and regio-selectivity for the 1,3,5-isomers, which is found to vary with the nature of the alkyne employed. This complex represents a convenient self-supported nickel(0) catalyst with no need for additional ligands and reducing agent.

Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA

An (η5-cyclopentadienyl)cobalt(i) complex was covalently incorporated into an engineered variant of the transmembrane protein ferric hydroxamate uptake protein component: A, FhuA ΔCVFtev, using a thiol-ene reaction. A CD spectrum shows the structural integrity of the biohybrid catalyst. MALDI-TOF of the segment containing the anchoring site for the cobalt complex Cys545 confirmed successful conjugation. This biohybrid catalyst catalyzed the cyclotrimerization of phenylacetylene to give a mixture of regioisomeric 1,2,4- and 1,3,5-triphenylbenzene in aqueous medium.