Welcome to LookChem.com Sign In|Join Free
  • or
1-(5-Phenylthien-2-yl)ethanone, also known as 1-(5-phenyl-thiophen-2-yl)ethanone, is a chemical compound characterized by the molecular formula C12H10OS. It is a yellow liquid with a molecular weight of 210.27 g/mol. 1-(5-Phenylthien-2-yl)ethanone serves as a versatile building block in the synthesis of various pharmaceuticals and other organic compounds, playing a significant role in research and development.

1665-41-4

Post Buying Request

1665-41-4 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1665-41-4 Usage

Uses

Used in Pharmaceutical Industry:
1-(5-Phenylthien-2-yl)ethanone is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of diverse molecules with potential medicinal properties.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(5-Phenylthien-2-yl)ethanone is utilized as a reagent, enabling the formation of a wide range of chemical compounds. Its presence in reactions can facilitate the synthesis of complex organic molecules, expanding the scope of chemical research.
Used in Chemical Production:
1-(5-Phenylthien-2-yl)ethanone also serves as a precursor in the production of various chemical compounds. Its involvement in the manufacturing process helps to create a broad spectrum of products, enhancing the versatility of the chemical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 1665-41-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,6 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1665-41:
(6*1)+(5*6)+(4*6)+(3*5)+(2*4)+(1*1)=84
84 % 10 = 4
So 1665-41-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H10OS/c1-9(13)11-7-8-12(14-11)10-5-3-2-4-6-10/h2-8H,1H3

1665-41-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(5-Phenylthiophen-2-yl)ethanone

1.2 Other means of identification

Product number -
Other names 5-phenyl-2-acetylthiophene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1665-41-4 SDS

1665-41-4Relevant academic research and scientific papers

Photoinduced Substitution Reactions in Halothiophene Derivatives. Steady State and Laser Flash Photolytic Studies

Elisei, F.,Latterini, L.,Aloisi, G. G.,D'Auria, M.

, p. 5365 - 5372 (1995)

A photochemical and photophysical study by steady state and pulsed techniques of 5-bromo- and 5-iodo-2-thiophenecarbaldehyde and 2-acetyl-5-iodothiophene in benzene is presented.The quantum yields for the direct and sensitized formation of the phenylthiophenes following the photocleavage of the carbon-halogen bond were determined in the 293-343 K temperature range.The transient species (triplets and free radicals) originated by laser excitation were investigated by laser flash photolysis; their spectral and kinetic properties and their formation quantum yields were determined at room temperature.The halogen atoms were detected through their interactions with teh solvent to form benzene-X. complexes that were identified by absorption spectra and decay lifetimes.The characteristics of the triplets were also determined in methylcyclohexane/3-methylpentane (9:1, v/v) at 77 K.Phosphorescence measurements at low temperature gave the spectral and kinetic characteristics of the lowest triplet states of halothiophenes.Through the effect of the solvent polarity on the triplet energy (ET), evidence was obtained of the n,?* nature of the lowest triplet.Results obtained by steady state and pulsed techniques gave strong indication that the sensitized photosubstitution takes place through an upper triplet state (likely ?,?* in nature) localized on the carbon-halogen bond.A scheme showing the energies of the involved electronic states is presented.For the direct photoreaction the main route is probably the triplet again, although a singlet pathway cannopt be excluded.

PEPPSI-Type Palladium–NHC Complexes: Synthesis, Characterization, and Catalytic Activity in the Direct C5-Arylation of 2-Substituted Thiophene Derivatives with Aryl Halides

Kalo?lu, Murat,?zdemir, ?smail,Dorcet, Vincent,Bruneau, Christian,Doucet, Henri

, p. 1382 - 1391 (2017)

Six benzimidazolium salts, having two nitrogen atoms substituted by various alkyl groups, have been synthesized in high yields. The benzimidazolium salts readily converted into the corresponding PEPPSI-type palladium–NHC complexes (PEPPSI = pyridine-enhan

Reusable, polymer-supported, palladium-catalyzed, atom-efficient coupling reaction of aryl halides with sodium tetraphenylborate in water by focused microwave irradiation

Bai, Lin,Wang, Jin-Xian

, p. 315 - 320 (2008)

A rapid and efficient cross-coupling reaction of sodium tetraphenylborate with aryl bromides was carried out in water at 120°C in the presence of a polymer-supported palladium catalyst and potassium carbonate under focused microwave irradiation. All four phenyl groups of sodium tetraphenylborate participated in the reaction and produced polyfunctional biaryls in excellent yields. The polymeric catalyst can be easily separated from the reaction mixture and reused more than 10 times without showing any decrease in activity.

New benzimidazolium N-heterocyclic carbene precursors and their related Pd-NHC complex PEPPSI-type: Synthesis, structures, DFT calculations, biological activity, docking study, and catalytic application in the direct arylation

?zdemir, ?smail,?zdemir, Nam?k,Bensouici, Chawki,Benzerka, Saida,Boulebd, Houssem,Gürbüz, Nevin,Khiri-Meribout, Naima,Sandeli, Abd El-Krim

, (2021/09/28)

New benzhydryl-5,6-dimethyl-(3-methylbenzyl)benzimidazolium salt as N-heterocyclic carbene precursors and their related new Pd-NHC complex PEPPSI-type with the general formula [PdBr2(NHC)(pyridine)] were prepared and theoretically studied. Quan

The first use of [PdBr2(imidazolidin-2-ylidene)(pyridine)] catalysts in the direct C-H bond arylation of C2-substituted furan and thiophene

Kalo?lu, Murat,Kalo?lu, Nazan,?zdemir, Nam?k,?zdemir, ?smail

, p. 2821 - 2843 (2021/04/21)

Abstract: N-Heterocyclic carbene (NHC)-linked PEPPSI-type palladium complexes have recently been used in the direct C-H bond arylation of heteroarenes. However, in most of the published works, NHC ligands containing benzimidazole and imidazole ring have b

Synthesis, characterization and catalytic activity of PEPPSI-type palladium–NHC complexes

?zdemir, Ismail,Gürbüz, Nevin,Hamdi, Naceur,Mansour, Lamjed,Slimani, Ichraf

, (2020/10/12)

Eight benzimidazolium salts (2a–h) with two nitrogen atoms substituted by various alkyl groups have been synthesized in high yields. The benzimidazolium salts were readily converted into the corresponding PEPPSI-type palladium–NHC complexes (PEPPSI = pyridine-enhanced precatalyst preparation, stabilization, and initiation) (3a–h). The structures of all compounds were characterized by 1H NMR, 13C NMR, and IR spectroscopy as well as by elemental analysis techniques, which support the proposed structures. The catalytic activity of the PEPPSI-type palladium–NHC complexes was evaluated with respect to the direct C5-arylation of 2-substituted heteroaryl derivatives (thiophene, furan and thiazole) with various aryl bromides. This arylation occurs efficiently and selectively at the C5-position of the 2-substituted thiophene, furan and thiazole derivatives.

1,3-Dioxane Functionalized Pd-PEPPSI Catalyst for Direct Arylation of Heteroaromatics

Ulu, ?znur Do?an

, (2021/08/09)

A series of benzimidazolium salts (1a-d) and their Pd-PEPPSI complexes (pyridine-enhanced precatalyst preparation, stabilization, and initiation) (2a-d) were prepared to catalyze the direct arylation of heteroaromatics (2-acetylthiophene and 2-furaldehyde) with various aryl bromides. The structures of all isolated compounds were elucidated based on spectroscopic methods (1H and 13C NMR, FT-IR and LC-MS spectroscopy). Under optimized reaction conditions, C5-arylated products were obtained in moderate to excellent yields in the direct arylation of heteroaromatics.

Direct arylation (hetero-coupling) of heteroarenes via unsymmetrical palladium-PEPPSI-NHC type complexes

?zdemir, ?smail,Ashfaq, Muhammad,Gürbüz, Nevin,Karci, Hüseyin,Naveed Zafar, Muhammad,Nawaz Tahir, Muhammad,Nawaz, Zahid

, (2021/08/16)

The growing interest of industry in the field of bi(hetero)arenes compounds, motivated us to synthesize these compounds via homogeneous catalytic route by using Pd PEPPSI-type complexes through direct arylation. In this work, the five new Pd PEPPSI-type c

Synthesis of [PdBr2(benzimidazole-2-ylidene)(pyridine)] complexes and their catalytic activity in the direct C[sbnd]H bond activation of 2-substituted heterocycles

Lasmari, Sarra,Gürbüz, Nevin,Boulcina, Raouf,?zdemir, Nam?k,?zdemir, ?smail

, (2021/02/27)

A series of unsymmetrical 1,3-disubstituted benzimidazolium chlorides, 2a-f, having two nitrogen atoms substituted by various alkyl groups were synthesized as N-heterocyclic carbene (NHC) precursors in high yields. The benzimidazolium salts are readily co

Synthesis, structures, DFT calculations, and catalytic application in the direct arylation of five-membered heteroarenes with aryl bromides of novel palladium-N-heterocyclic carbene PEPPSI-type complexes

?zdemir, ?smail,?zdemir, Nam?k,Benzerka, Saida,Boulebd, Houssem,Gürbüz, Nevin,Khiri-Meribout, Naima,el-Krim Sandeli, Abd

, p. 17878 - 17892 (2021/10/12)

A new series of Pd-catalysts based on an N-heterocyclic carbene PEPPSI-type ligand (PEPPSI = pyridine enhanced precatalyst preparation stabilization and initiation) with the general formula [Pd(ii)Br2(NHC)(pyridine)] was synthesized and fully characterize

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 1665-41-4