16728-56-6

Basic information

• Product Name: Pentanenitrile, 5-phenoxy-
• CAS NO: 16728-56-6
• Molecular Formula: C11H13NO
• Molecular Weight: 175.23
• Mol File: 16728-56-6.mol

Chemical Properties

• CAS DataBase Reference: Pentanenitrile, 5-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanenitrile, 5-phenoxy-(16728-56-6)
• EPA Substance Registry System: Pentanenitrile, 5-phenoxy-(16728-56-6)

Safety Data

• Hazardous Substances Data: 16728-56-6(Hazardous Substances Data)

Upstream product

• 6280-87-1 δ-chlorovaleronitrile 
• 139-02-6 sodium phenoxide 
• 1200-03-9 4-bromophenyl butyl ether 
• 143-33-9 sodium cyanide 
• 151-50-8 potassium cyanide 
• 5414-21-1 5-bromopentan-1-nitrile 
• 20549-72-8 4-phenoxybutyl iodide 
• 13049-65-5 Nitrilo-thioacetic acid S-phenyl ester 
• 24225-08-9 methanesulfonyl cyanide 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 2653-89-6 4-phenoxy-1-butene 
• 51354-18-8 Phosphorsaeure-diphenylestercyanid 

Downstream Products

• 70098-89-4 5-phenoxy-1-phenylpentan-1-one 
• 16728-67-9 5-phenoxypentylamine 
• 19176-64-8 Bis-<5-phenoxy-pentyl>-amin 
• 187807-61-0 1-phenoxy-5-decanone 
• 65851-20-9 6-phenoxy-hexan-2-one 
• 187807-49-4 (+/-)-1-phenoxy-5-hydroxydecane 
• 110010-49-6 [2-(4-Phenoxy-butyl)-1H-imidazol-4-yl]-methanol 
• 110010-83-8 [2-(4-Phenoxy-butyl)-1H-imidazol-4-yl]-acetonitrile 
• 408353-97-9 1,9-diphenoxy-nonan-5-one oxime 
• 7170-40-3 5-phenoxyvaleric acid 

Relevant articles and documents

Dehydrogenation of Primary Alkyl Azides to Nitriles Catalyzed by Pincer Iridium/Ruthenium Complexes

Pincer metal complexes exhibit superior catalytic activity in the dehydrogenation of plain alkanes, but find limited application in the dehydrogenation of functionalized organic molecules. Starting from easily accessible primary alkyl azides, here we report an efficient dehydrogenation of azides to nitriles using pincer iridium or ruthenium complexes as the catalysts. This method offers a route to cyanide-free preparation of nitriles without carbon chain elongation and without the use of strong oxidants. Both benzyl and linear aliphatic azides can be dehydrogenated with tert-butylethylene as the hydrogen acceptor to afford nitriles in moderate to high yields. Various functional groups can be tolerated, and the H?C?C?H bond dehydrogenation does not occur for linear alkyl azide substrates. Furthermore, the pincer Ir catalytic system was found to catalyze the direct azide dehydrogenation without the use of a sacrificial hydrogen acceptor.

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Cooperative Palladium/Lewis Acid-Catalyzed Transfer Hydrocyanation of Alkenes and Alkynes Using 1-Methylcyclohexa-2,5-diene-1-carbonitrile

Catalytic transfer hydrocyanation represents a clean and safe alternative to hydrocyanation processes using toxic HCN gas. Such reactions provide access to pharmaceutically important nitrile derivatives starting with alkenes and alkynes. Herein, an efficient and practical cooperative palladium/Lewis acid-catalyzed transfer hydrocyanation of alkenes and alkynes is presented using 1-methylcyclohexa-2,5-diene-1-carbonitrile as a benign and readily available HCN source. A large set of nitrile derivatives (>50 examples) are prepared from both aliphatic and aromatic alkenes with good to excellent anti-Markovnikov selectivity. A range of aliphatic alkenes engage in selective hydrocyanation to provide the corresponding nitriles. The introduced method is useful for chain walking hydrocyanation of internal alkenes to afford terminal nitriles in good regioselectivities. This protocol is also applicable to late-stage modification of bioactive molecules.

2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS

The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N', C', A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.

Radical cyanation of alkyl iodides with diethylphosphoryl cyanide

The β-elimination of an organophosphoryl group from an iminyl radical is observed for the first time. On the basis of this finding, radical cyanation of alkyl iodides is achieved by using diethylphosphoryl cyanide. Georg Thieme Verlag Stuttgart.

Radical cyanocarbonylation using alkyl allyl sulfone precursors

Acyl cyanides have been prepared by the three-component coupling reactions comprised of alkyl allyl sulfones, carbon monoxide, and p-tolylsulfonyl cyanide under tin-free radical reaction conditions. Georg Thieme Verlag Stuttgart.

Tin-free radical-mediated C-C-bond formations with alkyl allyl sulfones as radical precursors

Primary alkyl radicals are generated highly efficiently and reliably from alkyl allyl sulfone precursors. The latter are effective in tin-free radical C-C-bond formations, including cyanation, vinylation, and allylation (see scheme; V-40 = 1,1′-azobis(cyc

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Free radical-mediated carboxylation is achieved by treatment of alkyl iodides with S-phenyl chlorothioformate and bis(tributyltin) with irradiation at 300 nm.