167629-45-0Relevant academic research and scientific papers
Isolation and synthesis of a novel β-carboline guanidine derivative tiruchanduramine from the Indian ascidian Synoicum macroglossum
Ravinder,Vijender Reddy,Krishnaiah,Ramesh,Ramakrishna,Laatsch,Venkateswarlu
, p. 5475 - 5478 (2007/10/03)
The isolation and synthesis of the racemic form of a novel β-carboline guanidine alkaloid, tiruchanduramine, a potent α-glucosidase inhibitor from the Indian ascidian, Synoicum macroglossum has been achieved.
A facile and convergent synthesis of sarmentosin
Xu, Rui,Bai, Donglu
, p. 3355 - 3363 (2007/10/03)
A concise synthesis of sarmentosin (1) starting from butane-1,2,4-triol-1,2-acetonide is described. This convergent route can also be employed for the preparation of sarmentosin analogues for structure-activity relationship studies.
Synthesis of aglycon analogues of sarmentosin and their bioactivity of lymphocyte proliferation.
Zhang, Hong,Xu, Rui,Hu, Zhongliang,He, Xuchang,Bai, Donglu,Li, Xiaoyu,Wang, Xiaofeng
, p. 3543 - 3545 (2007/10/03)
A number of aglycon analogues of sarmentosin were prepared and their bioactivities on the proliferation of T-lymphocytes and B-lymphocytes were assayed.
Synthesis of unsaturated carboacyclic nucleoside analogues via Mitsunobu reactions
Du, Jinfa,Wang, Guangyi
, p. 867 - 879 (2007/10/03)
2-Substituted allyl alcohols 9 and 14 were prepared starting from butane-1,2,4-triol and glycerol, respectively. Mitsunobu condensations of 9 and 14 with purine and pyrimidine bases, followed by deprotection, afforded a number of acyclonucleosides having
Terminal fluoroolefins. The synthesis of novel carboacyclic nucleosides
Miller, Shawn C.,McCarthy, James R.,Sabol, Jeffrey S.
, p. 1099 - 1113 (2007/10/03)
A facile preparation of ketone 7 from butanetriol acetonide 5 is reported, and its utility for the synthesis of novel carboacyclic nucleosides 3E, 3Z, 4E and 4Z by the selective manipulation of multiple functionalities is demonstrated.
