167750-79-0

Usage

Uses

Used in Pharmaceutical Industry:
BENZYL-D7-AMINE is used as a building block for the synthesis of pharmaceuticals. Its deuterated form offers enhanced stability and resistance to metabolic degradation, which is crucial for the development of more effective and longer-lasting drugs.
Used in Agrochemical Industry:
In the agrochemical industry, BENZYL-D7-AMINE serves as a key component in the synthesis of various agrochemicals. Its deuterium substitution provides improved stability, ensuring the longevity and effectiveness of these compounds in agricultural applications.
Used in Materials Science:
BENZYL-D7-AMINE is utilized as a building block in materials science, contributing to the development of advanced materials with unique properties. The incorporation of deuterium isotopes can enhance the stability and performance of these materials, making them suitable for various applications.
Used as a Reagent in Organic Synthesis:
BENZYL-D7-AMINE is used as a reagent in organic synthesis, particularly in the preparation of deuterated compounds for research and development. Its deuterium substitution allows for the synthesis of isotopically labeled compounds, which are essential for studying reaction mechanisms, enhancing the understanding of chemical processes, and developing new synthetic methodologies.

Upstream product

• 59502-05-5 benzyl chloride-d7 
• 35656-93-0 perdeuteriobenzyl bromide 
• 2037-26-5 ⁽²⁾H₈-toluene 
• 167750-78-9 N-phthaloylbenzylamine 

Downstream Products

• 167750-76-7 N-(4-methyl-3-pentenyl)-(S)-prolinalbenzylimine 
• 1315578-06-3 6,8-dibromo-2-phenylquinazoline 
• 1315578-14-3 C₁₄H₃⁽²⁾H₅Br₂N₂ 
• 82-45-1 1-amino-9,10-anthracenedione 
• 610299-84-8 C₂₁H₉⁽²⁾H₁₄NS 
• 911207-06-2 C₂₁⁽²⁾H₁₄H₉ON 
• 911207-05-1 C₁₄⁽²⁾H₁₅N 

Relevant academic research and scientific papers

Probing Substrate Diffusion in Interstitial MOF Chemistry with Kinetic Isotope Effects

Metal–organic frameworks (MOFs) have garnered substantial interest as platforms for site-isolated catalysis. Efficient diffusion of small-molecule substrates to interstitial lattice-confined catalyst sites is critical to leveraging unique opportunities of

Diastereoselective Synthesis of α-Hydroxy- and α-Aminoindolizidines and -quinolizidines. Evidence for a Novel Cyclization/Hydride Migration Mechanism in the TiCl4-Induced Reaction of Prolinal Benzylimines by Deuterium Labelling Studies

Lewis acid-catalyzed of prolinal and 2-piperidinecarbaldehyde benzylimines 11, 12 results in the diastereoselective formation of α-amino-β-alkyl-substituted indolizidines 15, 17, 19, 21 and -quinolizidines 16, 18, 20, respectively.Both diastereoselectivit

Kinetics and product studies on Ullmann amination of 1-halogenoanthraquinones catalysed by copper(I)salts in acetonitrile solution

The kinetics and products of reactions of some primary amines (RNH2) with 1-halogenoanthraquininone (AQX) promoted by copper salts, particularly tetrakis(acetonitrile)copper(I) tetrafluoroborate, have been investigated in acetonitrile solution at 70 deg C.Provided that oxygen does not come into contact with solutions of the copper(I) salt and amine, the kinetics of the reactions have the simple form v = k, and the products consist almost entirely of the aminated anthraquinone, AQNHR, and dehalogenated material, AQH, their ratio being directly proportional to .The reaction rate is dependent on the identity of the departing halogen X, decreasing in the sequence I > Br > Cl, but the product ratio is little affected.N-Deuteration of the reactant amine gives rise to a small kinetic isotope effect, but the product ratio is unaffected.Conversely deutearation on the α-carbon atom of the amine has little kinetic effect but leads to a four-fold increase in the ratio of aminated to dehalogenated product.The observations are interpreted in terms of (i) formation of a copper(I)-amine complex, (II) activation of this species for attack on AQX by proton abstraction from an amine ligand by a free molecule (stepwise or concerted), and (iii) generation of an arylcopper(III) intermediate which is partitioned between formation of AQNHR by attack of an externel amine molecule and formation of AQH by an intramolecular process involving hydrogen transfer from the α-carbon atom in the amine ligand generated in (ii).Exposure of the initial copper(I)-amine complex to oxygen leads to a new complex, itself capable of reacting with AQX, which on prolonged incubation at 70 deg C in the presence of an excess of amine is transformed back to its original state.