167750-79-0

Basic information

• Product Name: BENZYL-D7-AMINE
• Synonyms: BENZYL-D7-AMINE
• CAS NO: 167750-79-0
• Molecular Formula: C₇H₉N
• Molecular Weight: 114.2
• Mol File: 167750-79-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZYL-D7-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL-D7-AMINE(167750-79-0)
• EPA Substance Registry System: BENZYL-D7-AMINE(167750-79-0)

Safety Data

• Hazardous Substances Data: 167750-79-0(Hazardous Substances Data)

Usage

General Description

Benzyl-d7-amine, also known as benzyl-d7-amine or alpha-benzyl-d7-amine, is a deuterated form of benzylamine, a colorless liquid with a strong ammonia-like odor. It is a derivative of benzene with a deuterium isotope substitution at the alpha carbon. Benzyl-d7-amine is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and materials science. It can also be used as a reagent in organic synthesis, especially in the preparation of deuterated compounds for research and development. The deuterated form of benzylamine offers improved stability and resistance to metabolic degradation, making it a valuable tool in drug discovery and development.

Upstream product

• 2037-26-5 ⁽²⁾H₈-toluene 
• 35656-93-0 perdeuteriobenzyl bromide 
• 59502-05-5 benzyl chloride-d7 
• 167750-78-9 N-phthaloylbenzylamine 

Downstream Products

• 610299-84-8 C₂₁H₉⁽²⁾H₁₄NS 
• 911207-06-2 C₂₁⁽²⁾H₁₄H₉ON 
• 911207-05-1 C₁₄⁽²⁾H₁₅N 
• 167750-76-7 N-(4-methyl-3-pentenyl)-(S)-prolinalbenzylimine 
• 82-45-1 1-amino-9,10-anthracenedione 
• 1315578-06-3 6,8-dibromo-2-phenylquinazoline 
• 1315578-14-3 C₁₄H₃⁽²⁾H₅Br₂N₂ 

Relevant articles and documents

Probing Substrate Diffusion in Interstitial MOF Chemistry with Kinetic Isotope Effects

Metal–organic frameworks (MOFs) have garnered substantial interest as platforms for site-isolated catalysis. Efficient diffusion of small-molecule substrates to interstitial lattice-confined catalyst sites is critical to leveraging unique opportunities of

Kinetics and product studies on Ullmann amination of 1-halogenoanthraquinones catalysed by copper(I)salts in acetonitrile solution

The kinetics and products of reactions of some primary amines (RNH2) with 1-halogenoanthraquininone (AQX) promoted by copper salts, particularly tetrakis(acetonitrile)copper(I) tetrafluoroborate, have been investigated in acetonitrile solution at 70 deg C.Provided that oxygen does not come into contact with solutions of the copper(I) salt and amine, the kinetics of the reactions have the simple form v = k, and the products consist almost entirely of the aminated anthraquinone, AQNHR, and dehalogenated material, AQH, their ratio being directly proportional to .The reaction rate is dependent on the identity of the departing halogen X, decreasing in the sequence I > Br > Cl, but the product ratio is little affected.N-Deuteration of the reactant amine gives rise to a small kinetic isotope effect, but the product ratio is unaffected.Conversely deutearation on the α-carbon atom of the amine has little kinetic effect but leads to a four-fold increase in the ratio of aminated to dehalogenated product.The observations are interpreted in terms of (i) formation of a copper(I)-amine complex, (II) activation of this species for attack on AQX by proton abstraction from an amine ligand by a free molecule (stepwise or concerted), and (iii) generation of an arylcopper(III) intermediate which is partitioned between formation of AQNHR by attack of an externel amine molecule and formation of AQH by an intramolecular process involving hydrogen transfer from the α-carbon atom in the amine ligand generated in (ii).Exposure of the initial copper(I)-amine complex to oxygen leads to a new complex, itself capable of reacting with AQX, which on prolonged incubation at 70 deg C in the presence of an excess of amine is transformed back to its original state.