21226-24-4

Basic information

• Product Name: Benzenesulfonamide, N-(4-iodophenyl)-
• Synonyms: Benzolsulfonsaeure-(4-jod-anilid);Benzolsulfonsaeure-<4-iod-anilid>;benzenesulfonic acid-(4-iodo-anilide);N-(4-Iodo-phenyl)-benzenesulfonamide;4-(Benzenesulfonylamino)-phenyl Iodide;N-(4-iodophenyl)benzenesulphonamide;N-(4-iodophenyl)benzenesulfonamide
• CAS NO: 21226-24-4
• Molecular Formula: C12H10INO2S
• Molecular Weight: 359.187
• Mol File: 21226-24-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 159 - 161 °C
• Boiling Point: 438.3±47.0 °C(Predicted)
• Density: 1.790±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenesulfonamide, N-(4-iodophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(4-iodophenyl)-(21226-24-4)
• EPA Substance Registry System: Benzenesulfonamide, N-(4-iodophenyl)-(21226-24-4)

Safety Data

• Hazardous Substances Data: 21226-24-4(Hazardous Substances Data)

Upstream product

• 636-98-6 p-nitrobenzene iodide 
• 98-80-6 phenylboronic acid 
• 873-55-2 sodium benzenesulfonate 
• 540-37-4 p-aminoiodobenzene 
• 98-10-2 benzenesulfonamide 
• 589-87-7 1,4-bromoiodobenzene 
• 1122-56-1 cyclohexylcarboxamide 
• 134305-16-1 N-chloro-N-phenylbenzenesulphonamide 
• 67-64-1 acetone 
• 1678-25-7 N-phenylbenzenesulfonamide 
• 7790-99-0 Iodine monochloride 
• 64-19-7 acetic acid 

Downstream Products

• 143937-66-0 N-(4-iodophenyl)-N-methylbenzenesulfonamide 
• 100-61-8 N-methylaniline 
• 102294-59-7 N-(4-iodophenyl)-methanesulfonamide 
• 501682-73-1 3-[4-(benzenesulfonylamino)phenyl]acrylic acid 
• 1035211-01-8 3-(4-benzenesulfonylamino-phenyl)-N-(tetrahydro-pyran-2-yloxy)-propionamide 
• 342373-30-2 3-(4-benzenesulfonylamino-phenyl)-propionic acid 
• 312-63-0 N-(4-fluorophenyl)benzenesulfonamide 
• 1678-25-7 N-phenylbenzenesulfonamide 

Relevant articles and documents

Sequential C-S and S-N Coupling Approach to Sulfonamides

A one-pot three-component reaction involving nitroarenes, (hetero)arylboronic acids, and potassium pyrosulfite leading to sulfonamides was described. A broad range of sulfonamides bearing different reactive functional groups were obtained in good to excellent yields through sequential C-S and S-N coupling that does not require metal catalysts.

UFU ('Ullmann-Finkelstein-Ullmann'): a new multicomponent reaction

We developed conditions to carry out the first 'one-pot' Ullmann-Finkelstein-Ullmann multicomponent reaction reported. This reaction allows the one-pot synthesis of dissymmetrical para-disubstituted benzene scaffold from 1-bromo-4-iodobenzene and two N-nu