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16830-24-3

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16830-24-3 Usage

General Description

2-methyl-4-pyridinecarboxylic acid methyl ester is a chemical compound with the molecular formula C8H9NO2. It is an ester derivative of 2-methyl-4-pyridinecarboxylic acid, and is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. It is a pale yellow to light brown crystalline powder, with a melting point of around 120-122°C. 2-methyl-4-pyridinecarboxylic acid methyl ester is known for its potential use as an inhibitor of catalase, an enzyme that plays a role in the breakdown of hydrogen peroxide in cells. It is important to handle this chemical with caution and use proper protective equipment, as it can be harmful if ingested, inhaled, or comes into contact with the skin.

Check Digit Verification of cas no

The CAS Registry Mumber 16830-24-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,3 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16830-24:
(7*1)+(6*6)+(5*8)+(4*3)+(3*0)+(2*2)+(1*4)=103
103 % 10 = 3
So 16830-24-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2/c1-6-5-7(3-4-9-6)8(10)11-2/h3-5H,1-2H3

16830-24-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methyl-4-Pyridinecarboxylic Acid Methyl Ester

1.2 Other means of identification

Product number -
Other names Methyl 2-methylisonicotinate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16830-24-3 SDS

16830-24-3Relevant articles and documents

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Nakamura et al.

, p. 488,489 (1979)

-

DIHYDROPYRIMIDINE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES

-

Page/Page column 39; 107, (2020/01/24)

The application describes dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

An anthrone-based Kv7.2/7.3 channel blocker with improved properties for the investigation of psychiatric and neurodegenerative disorders

Porter, Jacob D.,Vivas, Oscar,Weaver, C. David,Alsafran, Abdulmohsen,DiMilo, Elliot,Arnold, Leggy A.,Dickson, Eamonn J.,Dockendorff, Chris

supporting information, (2019/11/11)

A set of novel Kv7.2/7.3 (KCNQ2/3) channel blockers was synthesized to address several liabilities of the known compounds XE991 (metabolic instability and CYP inhibition) and the clinical compound DMP 543 (acid instability, insolubility, and lipophilicity). Using the anthrone scaffold of the prior channel blockers, alternative heteroarylmethyl substituents were installed via enolate alkylation reactions. Incorporation of a pyridazine and a fluorinated pyridine gave an analog (compound 18, JDP-107) with a promising combination of potency (IC50 = 0.16 μM in a Kv7.2 thallium flux assay), efficacy in a Kv7.2/7.3 patch clamp assay, and drug-like properties.

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