169036-71-9

Basic information

• Product Name: 1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE
• Synonyms: 1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE;1-(4-FLUOROPHENYL)-1H-PYRROLE-2-CARBOXALDEHYDE;1H-PYRROLE-2-CARBOXALDEHYDE, 1-(4-FLUOROPHENYL)-;1-(4-fluorophenyl)pyrrole-2-carbaldehyde
• CAS NO: 169036-71-9
• Molecular Formula: C₁₁H₈FNO
• Molecular Weight: 189.19
• Mol File: 169036-71-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE(169036-71-9)
• EPA Substance Registry System: 1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE(169036-71-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 169036-71-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE is used as a key building block in organic synthesis for the creation of various biologically active molecules. Its fluorine-substituted phenyl group and carbaldehyde functional group contribute to the structural diversity and reactivity of the synthesized compounds, enhancing their potential applications in various industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE serves as an essential component in the development of new drugs and therapeutic agents. Its unique structure allows for the design and synthesis of novel pharmaceuticals with improved efficacy, selectivity, and reduced side effects, addressing unmet medical needs and contributing to the advancement of healthcare.
Used in Pharmaceutical Research and Development:
1-(4-FLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE is employed as a crucial starting material in the research and development of innovative drugs and therapies. Its versatile chemical properties facilitate the exploration of new molecular targets and mechanisms of action, leading to the discovery of potential treatments for various diseases and conditions.
Used in Drug Design and Optimization:
This chemical compound is also utilized in the design and optimization of pharmaceuticals. Its incorporation into drug candidates can lead to improved pharmacokinetic and pharmacodynamic properties, such as enhanced solubility, stability, and bioavailability, ultimately resulting in more effective and safer medications.

Upstream product

• 371-40-4 4-fluoroaniline 
• 68-12-2 N,N-dimethyl-formamide 
• 81329-31-9 1-(4-fluorophenyl)-1H-pyrrole 

Downstream Products

• 288251-68-3 1-(4-fluorophenyl)pyrrole-3-carboxylic acid 
• 288249-81-0 N-[3-cyano-4-neopentyloxyphenyl]-1-(4-fluorophenyl)pyrrole-2-carboxamide 
• 288250-76-0 N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288249-78-5 ethyl N-(3-cyano-4-piperidinophenyl)-N-[1-(4-fluorophenyl)pyrrol-2-ylcarbonyl]glycine 
• 288250-13-5 N-{3-cyano-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}-1-(4-fluorophenyl)pyrrolecarboxamide 
• 1418313-47-9 ethyl N-(3-cyano-4-neopentyloxyphenyl)-N-[1-(4-fluorophenyl)pyrrole-3-carbonyl]glycine 
• 288249-74-1 N-(3-cyano-4-piperidinophenyl)-1-(4-fluorophenyl)pyrrole-2-carboxamide 
• 288249-80-9 N-[3-cyano-4-piperidinophenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288249-65-0 N-[3-cyano-4-(2,2,2-trifluoroethyl)phenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288251-69-4 1-(4-fluorophenyl)-3-formylpyrrole 
• 288251-67-2 1-(4-fluorophenyl)pyrrole-2-carboxylic acid 

Relevant articles and documents

AMIDOPYRIDINE DERIVATIVE, AND USE THEREOF

The present invention relates to novel amidopyridine derivatives. More specifically, the present invention provides a medicinal agent which is useful as a prophylactic or therapeutic agent for diseases based on the production of cytokines from T cells, comprising as the active ingredient an amidopyridine derivative or a pharmacologically acceptable salt thereof. Provided are an amidopyridine derivative of the following general formula (I): wherein each symbol has the same meaning as defined in the description, or a pharmacologically acceptable salt thereof.

AMIDE COMPOUNDS AND MEDICINAL USE THEREOF

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.